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Monitoring physiological responses to hemodynamic stress can help in determining appropriate treatment and ensuring good patient outcomes. Physicians' intuition suggests that the human body has a number of physiological response patterns to…

Machine Learning · Computer Science 2019-11-14 Chufan Gao , Fabian Falck , Mononito Goswami , Anthony Wertz , Michael R. Pinsky , Artur Dubrawski

The widespread availability of electronic health records (EHRs) promises to usher in the era of personalized medicine. However, the problem of extracting useful clinical representations from longitudinal EHR data remains challenging. In…

Machine Learning · Computer Science 2017-01-27 Zhengping Che , Yu Cheng , Zhaonan Sun , Yan Liu

Hepatocellular carcinoma (HCC) is a common type of liver cancer whose early-stage diagnosis is a common challenge, mainly due to the manual assessment of hematoxylin and eosin-stained whole slide images, which is a time-consuming process…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 Ajinkya Deshpande , Deep Gupta , Ankit Bhurane , Nisha Meshram , Sneha Singh , Petia Radeva

Survival risk stratification is an important step in clinical decision making for breast cancer management. We propose a novel deep learning approach for this purpose by integrating histopathological imaging, genetic and clinical data. It…

Computer Vision and Pattern Recognition · Computer Science 2024-02-20 Raktim Kumar Mondol , Ewan K. A. Millar , Arcot Sowmya , Erik Meijering

Predicting the incidence of complex chronic conditions such as heart failure is challenging. Deep learning models applied to rich electronic health records may improve prediction but remain unexplainable hampering their wider use in medical…

Objective: Reliable tools to predict moyamoya disease (MMD) patients at risk for hemorrhage could have significant value. The aim of this paper is to develop three machine learning classification algorithms to predict hemorrhage in moyamoya…

Machine Learning · Computer Science 2023-02-02 Meng Zhao , Yonggang Ma , Qian Zhang , Jizong Zhao

Computational fluid dynamics (CFD) based simulation of coronary blood flow provides valuable hemodynamic markers, such as pressure gradients, for diagnosing coronary artery disease (CAD). However, CFD is computationally expensive,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Rene Lisasi , Michele Esposito , Chen Zhao

Heart disease remains one of the leading causes of morbidity and mortality worldwide, necessitating the development of effective diagnostic tools to enable early diagnosis and clinical decision-making. This study evaluates the impact of…

Machine Learning · Computer Science 2025-03-24 Bilal Ahmad , Jinfu Chen , Haibao Chen

Accurate classification of breast cancer histopathology images is pivotal for early oncological diagnosis and therapeutic intervention.However, conventional deep learning architectures often encounter performance degradation under limited…

Computer Vision and Pattern Recognition · Computer Science 2026-02-11 Lin-Guo Gao , Suxing Liu

In patients with coronary artery stenoses of intermediate severity, the functional significance needs to be determined. Fractional flow reserve (FFR) measurement, performed during invasive coronary angiography (ICA), is most often used in…

Computer Vision and Pattern Recognition · Computer Science 2018-08-21 Majd Zreik , Nikolas Lessmann , Robbert W. van Hamersvelt , Jelmer M. Wolterink , Michiel Voskuil , Max A. Viergever , Tim Leiner , Ivana Išgum

Coronary Heart Disease affects millions of people worldwide and is a well-studied area of healthcare. There are many viable and accurate methods for the diagnosis and prediction of heart disease, but they have limiting points such as…

Artificial Intelligence · Computer Science 2024-09-24 Jamal Al-Karaki , Philip Ilono , Sanchit Baweja , Jalal Naghiyev , Raja Singh Yadav , Muhammad Al-Zafar Khan

Accurate prediction of medical conditions with straight past clinical evidence is a long-sought topic in the medical management and health insurance field. Although great progress has been made with machine learning algorithms, the medical…

Machine Learning · Computer Science 2024-12-06 Dongping Fang , Lian Duan , Xiaojing Yuan , Allyn Klunder , Kevin Tan , Suiting Cao , Yeqing Ji , Mike Xu

This study proposes a Transformer-based longitudinal modeling method to address challenges in clinical risk classification with heterogeneous Electronic Health Record (EHR) data, including irregular temporal patterns, large modality…

Machine Learning · Computer Science 2025-11-07 Anzhuo Xie , Wei-Chen Chang

Vascular calcification is implicated as an important factor in major adverse cardiovascular events (MACE), including heart attack and stroke. A controversy remains over how to integrate the diverse forms of vascular calcification into…

Computer Vision and Pattern Recognition · Computer Science 2024-01-18 Mehdi Ramezanpour , Anne M. Robertson , Yasutaka Tobe , Xiaowei Jia , Juan R. Cebral

Heart Disease has become one of the most serious diseases that has a significant impact on human life. It has emerged as one of the leading causes of mortality among the people across the globe during the last decade. In order to prevent…

Machine Learning · Computer Science 2022-06-08 Muhammad Salman Pathan , Avishek Nag , Muhammad Mohisn Pathan , Soumyabrata Dev

Hemodynamic quantities are valuable biomedical risk factors for cardiovascular pathology such as atherosclerosis. Non-invasive, in-vivo measurement of these quantities can only be performed using a select number of modalities that are not…

Quantitative Methods · Quantitative Biology 2026-02-23 Julian Suk , Dieuwertje Alblas , Barbara A. Hutten , Albert Wiegman , Christoph Brune , Pim van Ooij , Jelmer M. Wolterink

The point of care services and medication have become simpler with efficient consumer electronics devices in a smart healthcare system. Cardiovascular disease is a critical illness which causes heart failure, and early and prompt…

Computers and Society · Computer Science 2022-12-16 Nidhi Sinha , Teena Jangid , Amit M. Joshi , Saraju P. Mohanty

Hemodynamic parameters such as pressure and wall shear stress play an important role in diagnosis, prognosis, and treatment planning in cardiovascular diseases. These parameters can be accurately computed using computational fluid dynamics…

Computer Vision and Pattern Recognition · Computer Science 2025-08-28 Patryk Rygiel , Julian Suk , Kak Khee Yeung , Christoph Brune , Jelmer M. Wolterink

Cardiovascular disease (CVD) remains the leading cause of mortality worldwide, underscoring the need for reliable and efficient predictive tools that support early intervention. Traditional diagnostic approaches rely on handcrafted features…

Machine Learning · Computer Science 2025-12-17 Tejaswani Dash , Gautam Datla , Anudeep Vurity , Tazeem Ahmad , Mohd Adnan , Saima Rafi , Saisha Patro , Saina Patro

Multiple organ failure (MOF) is a life-threatening condition. Due to its urgency and high mortality rate, early detection is critical for clinicians to provide appropriate treatment. In this paper, we perform quantitative analysis on early…

Machine Learning · Computer Science 2021-04-26 Yuqing Wang , Yun Zhao , Rachael Callcut , Linda Petzold