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Risk stratification is a key tool in clinical decision-making, yet current approaches often fail to translate sophisticated survival analysis into actionable clinical criteria. We present a novel method for unsupervised machine learning…

Assessing coronary artery plaque segments in coronary CT angiography scans is an important task to improve patient management and clinical outcomes, as it can help to decide whether invasive investigation and treatment are necessary. In…

Cardiovascular diseases, including Heart Failure (HF), remain a leading global cause of mortality, often evading early detection. In this context, accessible and effective risk assessment is indispensable. Traditional approaches rely on…

Signal Processing · Electrical Eng. & Systems 2024-03-26 Sergio González , Abel Ko-Chun Yi , Wan-Ting Hsieh , Wei-Chao Chen , Chun-Li Wang , Victor Chien-Chia Wu , Shang-Hung Chang

Myocardial infarction and heart failure are major cardiovascular diseases that affect millions of people in the US. The morbidity and mortality are highest among patients who develop cardiogenic shock. Early recognition of cardiogenic shock…

Ischemic heart disease (IHD), particularly in its chronic stable form, is a subtle pathology due to its silent behavior before developing in unstable angina, myocardial infarction or sudden cardiac death. Machine learning techniques applied…

Signal Processing · Electrical Eng. & Systems 2020-11-20 Giulia Silveri , Marco Merlo , Luca Restivo , Gianfranco Sinagra , Agostino Accardo

Heart failure (HF) discharge planning depends on identifying patients at risk of deterioration or death, yet accurate prediction from routinely collected electronic health records (EHRs) remains challenging. We developed and validated…

Coronary artery disease, the leading cause of cardiovascular mortality worldwide, can be assessed non-invasively by coronary computed tomography angiography (CCTA). Despite progress in automated CCTA analysis using deep learning, clinical…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Jinkui Hao , Gorkem Durak , Halil Ertugrul Aktas , Ulas Bagci , Bradley D. Allen , Nilay S. Shah , Bo Zhou

Coronary heart disease (CHD) is a severe cardiac disease, and hence, its early diagnosis is essential as it improves treatment results and saves money on medical care. The prevailing development of quantum computing and machine learning…

Machine Learning · Computer Science 2024-10-02 Mehroush Banday , Sherin Zafar , Parul Agarwal , M Afshar Alam , Abubeker K M

An accurate assessment of the cardiovascular system and prediction of cardiovascular diseases (CVDs) are crucial. Measured cardiac blood flow data provide insights about patient-specific hemodynamics, where many specialized techniques have…

This study presents a novel methodology for stratifying post-myocardial infarction patients at risk of ventricular arrhythmias using patient-specific 3D cardiac models derived from late gadolinium enhancement cardiovascular magnetic…

Computational Engineering, Finance, and Science · Computer Science 2024-09-11 Dolors Serra , Pau Romero , Paula Franco , Ignacio Bernat , Miguel Lozano , Ignacio Garcia-Fernandez , David Soto , Antonio Berruezo , Oscar Camara , Rafael Sebastian

The importance of clinical variables in the prognosis of the disease is explained using statistical correlation or machine learning (ML). However, the predictive importance of these variables may not represent their causal relationships…

Machine Learning · Statistics 2025-06-04 Yina Hou , Shourav B. Rabbani , Liang Hong , Norou Diawara , Manar D. Samad

This study proposes a risk prediction method based on a Multi-Scale Temporal Alignment Network (MSTAN) to address the challenges of temporal irregularity, sampling interval differences, and multi-scale dynamic dependencies in Electronic…

Machine Learning · Computer Science 2025-11-27 Wei-Chen Chang , Lu Dai , Ting Xu

Breast cancer is a significant health concern affecting millions of women worldwide. Accurate survival risk stratification plays a crucial role in guiding personalised treatment decisions and improving patient outcomes. Here we present…

Computer Vision and Pattern Recognition · Computer Science 2024-07-02 Raktim Kumar Mondol , Ewan K. A. Millar , Arcot Sowmya , Erik Meijering

Cardiovascular disease remains a leading global cause of mortality, necessitating accurate risk prediction tools. Traditional methods, such as QRISK and the Framingham heart score, exhibit limitations in their ability to incorporate…

Genomics · Quantitative Biology 2024-02-12 Farnoush Shishehbori , Zainab Awan

Early screening for cancer has proven to improve the survival rate and spare patients from intensive and costly treatments due to late diagnosis. Cancer screening in the healthy population involves an initial risk stratification step to…

How well the heart is functioning can be quantified through measurements of myocardial deformation via echocardiography. Clinical assessment of cardiac function is generally focused on global indices of relative shortening, however,…

In this work, a novel approach is proposed for joint analysis of high dimensional time-resolved cardiac motion features obtained from segmented cardiac MRI and low dimensional clinical risk factors to improve survival prediction in heart…

Quantitative Methods · Quantitative Biology 2019-10-09 Shihao Jin , Nicolò Savioli , Antonio de Marvao , Timothy JW Dawes , Axel Gandy , Daniel Rueckert , Declan P O'Regan

The determination of a coronary stenosis and its severity in current clinical workflow is typically accomplished manually via physician visual assessment (PVA) during invasive coronary angiography. While PVA has shown large inter-rater…

Computer Vision and Pattern Recognition · Computer Science 2018-07-30 Benjamin Au , Uri Shaham , Sanket Dhruva , Georgios Bouras , Ecaterina Cristea , Alexandra Lansky MD , Andreas Coppi , Fred Warner , Shu-Xia Li , Harlan Krumholz

Cardiovascular diseases state as one of the greatest risks of death for the general population. Late detection in heart diseases highly conditions the chances of survival for patients. Age, sex, cholesterol level, sugar level, heart rate,…

Prognostication for comatose post-cardiac arrest patients is a critical challenge that directly impacts clinical decision-making in the ICU. Clinical information that informs prognostication is collected serially over time. Shortly after…

Machine Learning · Computer Science 2025-08-11 Xiaobin Shen , Jonathan Elmer , George H. Chen