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As a promising framework for resolving partial differential equations (PDEs), Physics-Informed Neural Networks (PINNs) have received widespread attention from industrial and scientific fields. However, lack of expressive ability and…

Machine Learning · Computer Science 2024-09-13 Feilong Jiang , Xiaonan Hou , Min Xia

Training of deep neural networks (DNNs) is a computationally intensive task and requires massive volumes of data transfer. Performing these operations with the conventional von Neumann architectures creates unmanageable time and power…

Emerging Technologies · Computer Science 2020-01-08 Murat Onen , Brenden A. Butters , Emily Toomey , Tayfun Gokmen , Karl K. Berggren

We introduce a deep learning architecture for structure-based virtual screening that generates fixed-sized fingerprints of proteins and small molecules by applying learnable atom convolution and softmax operations to each compound…

Cryo-electron microscopy (cryo-EM) has become a major experimental technique to determine the structures of large protein complexes and molecular assemblies, as evidenced by the 2017 Nobel Prize. Although cryo-EM has been drastically…

Biomolecules · Quantitative Biology 2021-06-01 Dong Si , Andrew Nakamura , Runbang Tang , Haowen Guan , Jie Hou , Ammaar Firozi , Renzhi Cao , Kyle Hippe , Minglei Zhao

This work presents an optical neuromorphic imaging and processing cytometry system that integrates an excitable VCSEL-based time-delayed (TD) extreme learning machine with an event-based 2D camera. The proposed system is designed for the…

Optics · Physics 2025-05-20 M. Skontranis , G. Moustakas , A. Bogris , C. Mesaritakis

Developing a bottom-up (molecular) theory for the electromechanical response of aperiodic materials is a prerequisite for understanding the piezoelectric properties of systems such as nanoparticles, (non-crystalline) polymers, or…

Chemical Physics · Physics 2017-07-25 Keith A. Werling , Geoffrey R. Hutchison , Daniel S. Lambrecht

Advanced radio-frequency pulse design used in magnetic resonance imaging has recently been demonstrated with deep learning of (convolutional) neural networks and reinforcement learning. For two-dimensionally selective radio-frequency…

Medical Physics · Physics 2022-01-24 Mads Sloth Vinding , Torben Ellegaard Lund

Deformable part models (DPMs) and convolutional neural networks (CNNs) are two widely used tools for visual recognition. They are typically viewed as distinct approaches: DPMs are graphical models (Markov random fields), while CNNs are…

Computer Vision and Pattern Recognition · Computer Science 2014-10-02 Ross Girshick , Forrest Iandola , Trevor Darrell , Jitendra Malik

The analysis of proteins in the gas phase benefits from detectors that exhibit high efficiency and precise spatial resolution. Although modern secondary electron multipliers already address numerous analytical requirements, new methods are…

The identification of DNA-binding proteins (DBPs) is essential due to their significant impact on various biological activities. Understanding the mechanisms underlying protein-DNA interactions is essential for elucidating various life…

Machine Learning · Computer Science 2026-01-27 A. Quadir , M. Sajid , M. Tanveer

This is a methodological guide to the use of deep neural networks in the processing of pulsed dipolar spectroscopy (PDS) data encountered in structural biology, organic photovoltaics, photosynthesis research, and other domains featuring…

Neuromorphic computing aims to reproduce the energy efficiency and adaptability of biological intelligence in hardware. Superconducting devices are an attractive platform due to their ultra-low dissipation and fast switching dynamics. Here…

Superconductivity · Physics 2026-02-17 Khalil Harrabi , Leonardo Cadorim , Milorad Milosevic

Nanophotonics provides the ability to rapidly and precisely reconfigure light beams on a compact platform. Infrared nanophotonic devices are widely used in data communications to overcome traditional bandwidth limitations of electrical…

The electron density is a key parameter to characterize any plasma. Most of the plasma applications and research in the area of low-temperature plasmas (LTPs) are based on the accurate estimations of plasma density and plasma temperature.…

Electron cryo-microscopy (cryo-EM) produces three-dimensional (3D) maps of the electrostatic potential of biological macromolecules, including proteins. Along with knowledge about the imaged molecules, cryo-EM maps allow de novo atomic…

Quantitative Methods · Quantitative Biology 2023-02-09 Kiarash Jamali , Dari Kimanius , Sjors H. W. Scheres

Current voltage (I-V) characteristics in proteins can be sensitive to conformational change induced by an external stimulus (photon, odour, etc.). This sensitivity can be used in medical and industrial applications besides shedding new…

Soft Condensed Matter · Physics 2015-05-28 Eleonora Alfinito , Jean-Francois Millithaler , Lino Reggiani

The interaction of condensed phase systems with external electric fields is crucial in myriad processes in nature and technology ranging from the field-directed motion of cells (galvanotaxis), to energy storage and conversion systems…

Chemical Physics · Physics 2024-09-25 Kit Joll , Philipp Schienbein , Kevin M. Rosso , Jochen Blumberger

Background: Single-particle cryo-electron microscopy (cryo-EM) has become a popular tool for structural determination of biological macromolecular complexes. High-resolution cryo-EM reconstruction often requires hundreds of thousands of…

Data Analysis, Statistics and Probability · Physics 2017-09-05 Yanan Zhu , Qi Ouyang , Youdong Mao

This paper presents a neural vocoder based on a denoising diffusion probabilistic model (DDPM) incorporating explicit periodic signals as auxiliary conditioning signals. Recently, DDPM-based neural vocoders have gained prominence as…

Audio and Speech Processing · Electrical Eng. & Systems 2024-02-23 Yukiya Hono , Kei Hashimoto , Yoshihiko Nankaku , Keiichi Tokuda

Dynamic nuclear polarization (DNP) has revolutionized the field of NMR spectroscopy, expanding its reach and capabilities to investigate diverse materials, biomolecules, and complex dynamic processes. Bringing high-efficiency DNP to the…

Mesoscale and Nanoscale Physics · Physics 2024-02-27 Sahand Tabatabaei , Pritam Priyadarsi , Namanish Singh , Pardis Sahafi , Daniel Tay , Andrew Jordan , Raffi Budakian
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