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Related papers: Proteinoid microspheres as proto-neural networks

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Proteinoids -- thermal proteins -- are produced by heating amino acids to their melting point and initiation of polymerisation to produce polymeric chains. Proteinoids swell in aqueous solution into hollow microspheres. The proteinoid…

Emerging Technologies · Computer Science 2021-06-03 Andrew Adamatzky

Proteinoids, or thermal proteins, are inorganic entities formed by heating amino acids to their melting point and commencing polymerisation to form polymeric chains. Typically, their diameters range from 10 to 100 micron. Some amino acids…

Emerging Technologies · Computer Science 2023-02-13 Panagiotis Mougkogiannis , Neil Phillips , Andrew Adamatzky

Proteinoids are thermal proteins which form microspheres in water in presence of salt. Ensembles of proteinoid microspheres exhibit passive non-linear electrical properties and active neuron-like spiking of electrical potential. We propose…

Emerging Technologies · Computer Science 2023-06-27 Panagiotis Mougkogiannis , Andrew Adamatzky

Proteinoids are solidified gels made from poly(amino acids) based polymers that exhibit oscillatory electrical activity. It has been proposed that proteinoids are capable of performing analog computing as their electrical activity can be…

Proteinoids, or thermal proteins, are produced by heating amino acids to their melting point and initiation of polymerisation to produce polymeric chains. In aqueous solutions proteinoids swell into hollow microspheres. These microspheres…

Emerging Technologies · Computer Science 2023-03-31 Panagiotis Mougkogiannis , Andrew Adamatzky

Proteinoids (thermal proteins) are produced by heating amino acids to their melting point and initiation of polymerisation to produce polymeric chains. Amino acid-like molecules, or proteinoids, can condense at high temperatures to create…

Materials Science · Physics 2023-02-14 Panagiotis Mougkogiannis , Andrew Adamatzky

In recent work we reported the vibrational spectrum of more than 100,000 known protein structures, and a self-consistent sonification method to render the spectrum in the audible range of frequencies (Extreme Mechanics Letters, 2019). Here…

Biological Physics · Physics 2020-04-17 Markus J. Buehler

Protocells are a type of synthetic cells, which, if engineered to have properties similar to a natural cell, can have immense applications in synthetic biology and bioengineering communities. Proteinoids are one of the leading contenders…

Fluid Dynamics · Physics 2022-12-13 Saksham Sharma , Panagiotis Mougoyannis , Giuseppe Tarabella , Andrew Adamatzky

This paper presents a molecular mechanics study using a molecular dynamics software (NAMD) coupled to virtual reality (VR) techniques for intuitive Bio-NanoRobotic prototyping. Using simulated Bio-Nano environments in VR, the operator can…

Biological Physics · Physics 2007-08-15 Mustapha Hamdi , Gaurav Sharma , A. Ferreira , Constantinos Mavroidis

In recent years, deep learning techniques have made significant strides in molecular generation for specific targets, driving advancements in drug discovery. However, existing molecular generation methods present significant limitations:…

Machine Learning · Computer Science 2025-03-12 Taojie Kuang , Qianli Ma , Athanasios V. Vasilakos , Yu Wang , Qiang , Cheng , Zhixiang Ren

We report a multi-modal spiking neuron that allows optical and electronic input and control, and wavelength-multiplexing operation, for use in novel high-speed neuromorphic sensing and computing functionalities. The photonic-electronic…

The interaction of a protein with its environment can be understood and controlled via its 3D structure. Experimental methods for protein structure determination, such as X-ray crystallography or cryogenic electron microscopy, shed light on…

Machine Learning · Computer Science 2025-04-24 Axel Levy , Eric R. Chan , Sara Fridovich-Keil , Frédéric Poitevin , Ellen D. Zhong , Gordon Wetzstein

Electronically conductive protein-based materials could enable the creation of bioelectronic components and devices from sustainable and nontoxic materials, while also being well-suited to interface with biological systems, such as living…

A class of analog computers built from large numbers of microscopic probabilistic machines is discussed. It is postulated that such computers are implemented in biological systems as ensembles of protein molecules. The formalism is based on…

Biological Physics · Physics 2008-06-24 Victor Eliashberg

Proteinoids, as soft matter fluidic systems, are computational substrates that have been recently proposed for their analog computing capabilities. Such systems exhibit oscillatory electrical activity because of cationic and anionic…

In this project, we present a deep neural network (DNN)-based biophysics model that uses multi-scale and uniform topological and electrostatic features to predict protein properties, such as Coulomb energies or solvation energies. The…

Machine Learning · Computer Science 2026-03-16 Elyssa Sliheet , Md Abu Talha , Weihua Geng

Molecular motor proteins form the basis of cellular dynamics. Recently, notable efforts have led to the creation of their DNA-based mimics, which can carry out complex nanoscale motion. However, such functional analogues have not yet been…

Biological Physics · Physics 2021-05-14 Kerstin Goepfrich , Maximilian J. Urban , Christoph Frey , Ilia Platzman , Joachim P. Spatz , Na Liu

Neuromorphic computing-modelled after the functionality and efficiency of biological neural systems-offers promising new directions for advancing artificial intelligence and computational models. Photonic techniques for neuromorphic…

Diffusive memristors owing to their ability to produce current spiking when a constant or slowly changing voltage is applied are competitive candidates for the development of artificial electronic neurons. These artificial neurons can be…

Proteins are the active working horses in our body. These biomolecules perform all vital cellular functions from DNA replication and general biosynthesis to metabolic signaling and environmental sensing. While static 3D structures are now…

Quantitative Methods · Quantitative Biology 2020-10-16 Sonja Schmid , Cees Dekker
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