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Optical diffraction tomography (ODT) reconstructs a samples volumetric refractive index (RI) to create high-contrast, quantitative 3D visualizations of biological samples. However, standard implementations of ODT use interferometric…

Image and Video Processing · Electrical Eng. & Systems 2024-12-13 Shwetadwip Chowdhury , Michael Chen , Regina Eckert , David Ren , Fan Wu , Nicole Repina , Laura Waller

Optical Diffraction Tomography (ODT) is a powerful non-invasive imaging technique widely used in biological and medical applications. While significant progress has been made in transmission configuration, reflection ODT remains challenging…

Optics · Physics 2026-05-14 Thomas Wasik , Victor Barolle , Alexandre Aubry , Josselin Garnier

The refractive index (RI) of cells and tissues is crucial in pathophysiology as a noninvasive and quantitative imaging contrast. Although its measurements have been demonstrated using three-dimensional quantitative phase imaging methods,…

Refractive Index Tomography is the inverse problem of reconstructing the continuously-varying 3D refractive index in a scene using 2D projected image measurements. Although a purely refractive field is not directly visible, it bends light…

Computer Vision and Pattern Recognition · Computer Science 2023-12-06 Brandon Zhao , Aviad Levis , Liam Connor , Pratul P. Srinivasan , Katherine L. Bouman

This work introduces a novel reinterpretation of structured illumination (SI) microscopy for coherent imaging that allows three-dimensional imaging of complex refractive index (RI). To do so, we show that coherent SI is mathematically…

Optics · Physics 2017-05-11 Shwetadwip Chowdhury , Will J. Eldridge , Adam Wax , Joseph A. Izatt

Label-free tomographic microscopy offers a compelling means to visualize three-dimensional (3D) refractive index (RI) distributions from two-dimensional (2D) intensity measurements. However, limited forward-model accuracy and the ill-posed…

Optics · Physics 2025-02-27 Delong Yang , Shaohui Zhang , Jiasong Sun , Chao Zuo , Qun Hao

We propose a novel intensity diffraction tomography (IDT) reconstruction algorithm based on the split-step non-paraxial (SSNP) model for recovering the 3D refractive index (RI) distribution of multiple-scattering biological samples.…

Optics · Physics 2022-09-09 Jiabei Zhu , Hao Wang , Lei Tian

Optical diffraction tomography (ODT) is an emerging 3D imaging technique that is used for the 3D reconstruction of the refractive index (RI) for semi-transparent samples. Various inverse models have been proposed to reconstruct the 3D RI…

Optics · Physics 2022-06-13 Ahmed B. Ayoub , Amirhossein Saba , Carlo Gigli , Demetri Psaltis

Image reconstruction under multiple light scattering is crucial in a number of applications such as diffraction tomography. The reconstruction problem is often formulated as a nonconvex optimization, where a nonlinear measurement model is…

Computer Vision and Pattern Recognition · Computer Science 2018-07-04 Yu Sun , Zhihao Xia , Ulugbek S. Kamilov

Despite recent progress on semantic segmentation, there still exist huge challenges in medical ultra-resolution image segmentation. The methods based on multi-branch structure can make a good balance between computational burdens and…

Computer Vision and Pattern Recognition · Computer Science 2020-02-20 Tong Wu , Yuan Xie , Yanyun Qu , Bicheng Dai , Shuxin Chen

Optical diffraction tomography (ODT) provides three-dimensional refractive index (RI) tomograms of a transparent microscopic object. However, because of the finite numerical aperture of objective lenses, ODT has the limited access to…

Optics · Physics 2017-11-22 Moosung Lee , Seungwoo Shin , YongKeun Park

Magnetic Resonance Imaging (MRI) is one of the most flexible and powerful medical imaging modalities. This flexibility does however come at a cost; MRI images acquired at different sites and with different parameters exhibit significant…

This paper presents a Multispectral imaging (MSI) approach that combines the use of a diffractive optical element, and a deep learning algorithm for spectral reconstruction. Traditional MSI techniques often face challenges such as high…

Image and Video Processing · Electrical Eng. & Systems 2023-10-06 Khen Cohen , Tuval Kay

Simultaneous imaging of fluorescence-labeled and label-free phase objects in the same sample provides distinct and complementary information. Most multimodal fluorescence-phase imaging operates in transmission mode, capturing fluorescence…

Optics · Physics 2024-08-20 Renzhi He , Yucheng Li , Junjie Chen , Yi Xue

Referring Remote Sensing Image Segmentation (RRSIS) is a new challenge that combines computer vision and natural language processing, delineating specific regions in aerial images as described by textual queries. Traditional Referring Image…

Computer Vision and Pattern Recognition · Computer Science 2024-04-03 Sihan Liu , Yiwei Ma , Xiaoqing Zhang , Haowei Wang , Jiayi Ji , Xiaoshuai Sun , Rongrong Ji

Recently, Magnetic Resonance Fingerprinting (MRF) was proposed as a quantitative imaging technique for the simultaneous acquisition of tissue parameters such as relaxation times $T_1$ and $T_2$. Although the acquisition is highly…

Image and Video Processing · Electrical Eng. & Systems 2019-07-23 Elisabeth Hoppe , Florian Thamm , Gregor Körzdörfer , Christopher Syben , Franziska Schirrmacher , Mathias Nittka , Josef Pfeuffer , Heiko Meyer , Andreas Maier

Magnetic resonance imaging (MRI) is widely used for screening, diagnosis, image-guided therapy, and scientific research. A significant advantage of MRI over other imaging modalities such as computed tomography (CT) and nuclear imaging is…

Image and Video Processing · Electrical Eng. & Systems 2020-02-20 Qing Lyu , Hongming Shan , Ge Wang

Magnetic resonance imaging (MRI) is an important non-invasive clinical tool that can produce high-resolution and reproducible images. However, a long scanning time is required for high-quality MR images, which leads to exhaustion and…

Image and Video Processing · Electrical Eng. & Systems 2022-04-12 Jiahao Huang , Yingying Fang , Yinzhe Wu , Huanjun Wu , Zhifan Gao , Yang Li , Javier Del Ser , Jun Xia , Guang Yang

Magnetic Resonance Imaging (MRI) plays a crucial role in brain disease diagnosis, but it is not always feasible for certain patients due to physical or clinical constraints. Recent studies attempt to synthesize MRI from Computed Tomography…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Junming Liu , Yifei Sun , Weihua Cheng , Yujin Kang , Yirong Chen , Ding Wang , Guosun Zeng

Objective: To allow efficient learning using the Recurrent Inference Machine (RIM) for image reconstruction whereas not being strictly dependent on the training data distribution so that unseen modalities and pathologies are still…

Image and Video Processing · Electrical Eng. & Systems 2020-12-15 Dimitrios Karkalousos , Kai Lønning , Hanneke E. Hulst , Serge O. Dumoulin , Jan-Jakob Sonke , Frans M. Vos , Matthan W. A. Caan
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