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Computed tomography (CT) and clinical numeric data are essential modalities for cancer evaluation, but building large-scale multimodal training datasets for developing medical foundation models remains challenging due to the structural…

Computer Vision and Pattern Recognition · Computer Science 2025-01-24 Daeun Jung , Jaehyeok Jang , Sooyoung Jang , Yu Rang Park

Morphological attributes from histopathological images and molecular profiles from genomic data are important information to drive diagnosis, prognosis, and therapy of cancers. By integrating these heterogeneous but complementary data, many…

Machine Learning · Computer Science 2022-02-28 Kaiwen Tan , Weixian Huang , Xiaofeng Liu , Jinlong Hu , Shoubin Dong

Recently, various contrastive learning techniques have been developed to categorize time series data and exhibit promising performance. A general paradigm is to utilize appropriate augmentations and construct feasible positive samples such…

Machine Learning · Computer Science 2024-10-11 Qianying Ren , Dongsheng Luo , Dongjin Song

Molecular Machine Learning (ML) bears promise for efficient molecule property prediction and drug discovery. However, labeled molecule data can be expensive and time-consuming to acquire. Due to the limited labeled data, it is a great…

Machine Learning · Computer Science 2022-04-01 Yuyang Wang , Jianren Wang , Zhonglin Cao , Amir Barati Farimani

Contrastive Learning (CL) enhances the training of sequential recommendation (SR) models through informative self-supervision signals. Existing methods often rely on data augmentation strategies to create positive samples and promote…

Information Retrieval · Computer Science 2026-04-06 Zhikai Wang , Yanyan Shen , Zexi Zhang , Li He , Yichun Li , Hao Gu , Yinghua Zhang

Lung cancer is one of the death threatening diseases among human beings. Early and accurate detection of lung cancer can increase the survival rate from lung cancer. Computed Tomography (CT) images are commonly used for detecting the lung…

Machine Learning · Statistics 2019-11-26 Md Rashidul Hasan , Muntasir Al Kabir

Accurate and robust drug response prediction is of utmost importance in precision medicine. Although many models have been developed to utilize the representations of drugs and cancer cell lines for predicting cancer drug responses (CDR),…

Quantitative Methods · Quantitative Biology 2023-11-22 Xiaoqiong Xia , Chaoyu Zhu , Yuqi Shan , Fan Zhong , Lei Liu

Building a highly accurate predictive model for classification and localization of abnormalities in chest X-rays usually requires a large number of manually annotated labels and pixel regions (bounding boxes) of abnormalities. However, it…

Computer Vision and Pattern Recognition · Computer Science 2022-05-06 Yan Han , Chongyan Chen , Ahmed Tewfik , Benjamin Glicksberg , Ying Ding , Yifan Peng , Zhangyang Wang

Recent years have seen great advancements in the development of deep learning models for histopathology image analysis in digital pathology applications, evidenced by the increasingly common deployment of these models in both research and…

Image and Video Processing · Electrical Eng. & Systems 2022-08-09 Veena Kaustaban , Qinle Ba , Ipshita Bhattacharya , Nahil Sobh , Satarupa Mukherjee , Jim Martin , Mohammad Saleh Miri , Christoph Guetter , Amal Chaturvedi

Early detection of lung cancer is essential in reducing mortality. Recent studies have demonstrated the clinical utility of low-dose computed tomography (CT) to detect lung cancer among individuals selected based on very limited clinical…

Computer Vision and Pattern Recognition · Computer Science 2019-02-25 Jiachen Wang , Riqiang Gao , Yuankai Huo , Shunxing Bao , Yunxi Xiong , Sanja L. Antic , Travis J. Osterman , Pierre P. Massion , Bennett A. Landman

The success of deep learning heavily depends on the availability of large labeled training sets. However, it is hard to get large labeled datasets in medical image domain because of the strict privacy concern and costly labeling efforts.…

Computer Vision and Pattern Recognition · Computer Science 2021-09-30 Dewen Zeng , Yawen Wu , Xinrong Hu , Xiaowei Xu , Haiyun Yuan , Meiping Huang , Jian Zhuang , Jingtong Hu , Yiyu Shi

Contrastive self-supervised learning (SSL) learns an embedding space that maps similar data pairs closer and dissimilar data pairs farther apart. Despite its success, one issue has been overlooked: the fairness aspect of representations…

A definitive diagnosis of a brain tumour is essential for enhancing treatment success and patient survival. However, it is difficult to manually evaluate multiple magnetic resonance imaging (MRI) images generated in a clinic. Therefore,…

Neural and Evolutionary Computing · Computer Science 2022-04-27 Amin Abdollahi Dehkordi , Mina Hashemi , Mehdi Neshat , Seyedali Mirjalili , Ali Safaa Sadiq

Background and Objective: Given the high heterogeneity and clinical diversity of cancer, substantial variations exist in multi-omics data and clinical features across different cancer subtypes. Methods: We propose a model, named DEDUCE,…

Machine Learning · Computer Science 2024-10-29 Liangrui Pan , Xiang Wang , Qingchun Liang , Jiandong Shang , Wenjuan Liu , Liwen Xu , Shaoliang Peng

Early detection of lung cancer is critical to improving survival outcomes. We present a deep learning framework for automated lung cancer screening from chest computed tomography (CT) images with integrated explainability. Using the…

Image and Video Processing · Electrical Eng. & Systems 2026-01-07 Nishan Rai , Sujan Khatri , Devendra Risal

With the long-term rapid increase in incidences of colorectal cancer (CRC), there is an urgent clinical need to improve risk stratification. The conventional pathology report is usually limited to only a few histopathological features.…

Image and Video Processing · Electrical Eng. & Systems 2020-07-08 Christian Abbet , Inti Zlobec , Behzad Bozorgtabar , Jean-Philippe Thiran

Motivation. Cancer heterogeneity is observed at multiple biological levels. To improve our understanding of these differences and their relevance in medicine, approaches to link organ- and tissue-level information from diagnostic images and…

Quantitative Methods · Quantitative Biology 2020-05-19 Nova F. Smedley , Suzie El-Saden , William Hsu

Skin image datasets often suffer from imbalanced data distribution, exacerbating the difficulty of computer-aided skin disease diagnosis. Some recent works exploit supervised contrastive learning (SCL) for this long-tailed challenge.…

Computer Vision and Pattern Recognition · Computer Science 2023-07-11 Yilan Zhang , Jianqi Chen , Ke Wang , Fengying Xie

Recent work has shown the potential of graph neural networks to efficiently predict material properties, enabling high-throughput screening of materials. Training these models, however, often requires large quantities of labelled data,…

Machine Learning · Computer Science 2022-11-28 Teddy Koker , Keegan Quigley , Will Spaeth , Nathan C. Frey , Lin Li

Self-supervised learning (SSL) has emerged as a powerful paradigm for Chest X-ray (CXR) analysis under limited annotations. Yet, existing SSL strategies remain suboptimal for medical imaging. Masked image modeling allocates substantial…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 Wangyu Feng , Shawn Young , Lijian Xu