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Learning useful data representations without requiring labels is a cornerstone of modern deep learning. Self-supervised learning methods, particularly contrastive learning (CL), have proven successful by leveraging data augmentations to…

Machine Learning · Computer Science 2023-12-11 Sacha Morin , Somjit Nath , Samira Ebrahimi Kahou , Guy Wolf

A good clustering algorithm can discover natural groupings in data. These groupings, if used wisely, provide a form of weak supervision for learning representations. In this work, we present Clustering-based Contrastive Learning (CCL), a…

Computer Vision and Pattern Recognition · Computer Science 2020-04-07 Vivek Sharma , Makarand Tapaswi , M. Saquib Sarfraz , Rainer Stiefelhagen

Self-supervised learning (SSL) is a method that learns the data representation by utilizing supervision inherent in the data. This learning method is in the spotlight in the drug field, lacking annotated data due to time-consuming and…

Biomolecules · Quantitative Biology 2022-08-19 Kisung Moon , Sunyoung Kwon

Self-Supervised Contrastive Learning has proven effective in deriving high-quality representations from unlabeled data. However, a major challenge that hinders both unimodal and multimodal contrastive learning is feature suppression, a…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Jihai Zhang , Xiang Lan , Xiaoye Qu , Yu Cheng , Mengling Feng , Bryan Hooi

Background and Purpose: Convolutional neural network is widely used for image recognition in the medical area at nowadays. However, overall accuracy in predicting lung tumor is low and the processing time is high as the error occurred while…

Image and Video Processing · Electrical Eng. & Systems 2022-08-15 Bhoj Raj Pandit , Abeer Alsadoon , P. W. C. Prasad , Sarmad Al Aloussi , Tarik A. Rashid , Omar Hisham Alsadoon , Oday D. Jerew

Predicting the likelihood of survival is of paramount importance for individuals diagnosed with cancer as it provides invaluable information regarding prognosis at an early stage. This knowledge enables the formulation of effective…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Numan Saeed , Muhammad Ridzuan , Fadillah Adamsyah Maani , Hussain Alasmawi , Karthik Nandakumar , Mohammad Yaqub

Complete removal of cancer tumors with a negative specimen margin during lumpectomy is essential in reducing breast cancer recurrence. However, 2D specimen radiography (SR), the current method used to assess intraoperative specimen margin…

Computer Vision and Pattern Recognition · Computer Science 2025-06-27 Tyler Ward , Xiaoqin Wang , Braxton McFarland , Md Atik Ahamed , Sahar Nozad , Talal Arshad , Hafsa Nebbache , Jin Chen , Abdullah Imran

Cell identification within the H&E slides is an essential prerequisite that can pave the way towards further pathology analyses including tissue classification, cancer grading, and phenotype prediction. However, performing such a task using…

Computer Vision and Pattern Recognition · Computer Science 2023-01-18 Ramin Nakhli , Amirali Darbandsari , Hossein Farahani , Ali Bashashati

This paper considers contrastive training for cross-modal 0-shot transfer wherein a pre-trained model in one modality is used for representation learning in another domain using pairwise data. The learnt models in the latter domain can then…

Genetic studies have identified associations between gene mutations and clear cell renal cell carcinoma (ccRCC). Because the complete gene mutational landscape cannot be characterized through biopsy and sequencing assays for each patient,…

Self-supervised learning has proven to be an effective way to learn representations in domains where annotated labels are scarce, such as medical imaging. A widely adopted framework for this purpose is contrastive learning and it has been…

Computer Vision and Pattern Recognition · Computer Science 2024-02-23 Hugo Figueiras , Helena Aidos , Nuno Cruz Garcia

This paper studies the problem of graph-level clustering, which is a novel yet challenging task. This problem is critical in a variety of real-world applications such as protein clustering and genome analysis in bioinformatics. Recent years…

Machine Learning · Computer Science 2023-03-09 Wei Ju , Yiyang Gu , Binqi Chen , Gongbo Sun , Yifang Qin , Xingyuming Liu , Xiao Luo , Ming Zhang

Contrastive learning based on instance discrimination trains model to discriminate different transformations of the anchor sample from other samples, which does not consider the semantic similarity among samples. This paper proposes a new…

Computer Vision and Pattern Recognition · Computer Science 2021-10-19 Hao Li , Xiaopeng Zhang , Hongkai Xiong

Machine learning (ML) approaches have been used to develop highly accurate and efficient applications in many fields including bio-medical science. However, even with advanced ML techniques, cancer classification using gene expression data…

Genomics · Quantitative Biology 2023-05-10 Mahmood Khalsan , Mu Mu , Eman Salih Al-Shamery , Lee Machado , Suraj Ajit , Michael Opoku Agyeman

We discuss a cancer hallmark network framework for modelling genome-sequencing data to predict cancer clonal evolution and associated clinical phenotypes. Strategies of using this framework in conjunction with genome sequencing data in an…

Molecular Networks · Quantitative Biology 2014-08-12 Edwin Wang , Naif Zaman , Shauna Mcgee , Jean-Sébastien Milanese , Ali Masoudi-Nejad , Maureen O'Connor

Unsupervised cell type identification is crucial for uncovering and characterizing heterogeneous populations in single cell omics studies. Although a range of clustering methods have been developed, most focus exclusively on intrinsic…

Artificial Intelligence · Computer Science 2025-12-12 Liang Peng , Haopeng Liu , Yixuan Ye , Cheng Liu , Wenjun Shen , Si Wu , Hau-San Wong

The healthcare industry generates troves of unlabelled physiological data. This data can be exploited via contrastive learning, a self-supervised pre-training method that encourages representations of instances to be similar to one another.…

Machine Learning · Computer Science 2021-05-18 Dani Kiyasseh , Tingting Zhu , David A. Clifton

We present Cycle-Contrastive Learning (CCL), a novel self-supervised method for learning video representation. Following a nature that there is a belong and inclusion relation of video and its frames, CCL is designed to find correspondences…

Computer Vision and Pattern Recognition · Computer Science 2020-10-29 Quan Kong , Wenpeng Wei , Ziwei Deng , Tomoaki Yoshinaga , Tomokazu Murakami

The classification of medical images is a pivotal aspect of disease diagnosis, often enhanced by deep learning techniques. However, traditional approaches typically focus on unimodal medical image data, neglecting the integration of diverse…

Image and Video Processing · Electrical Eng. & Systems 2025-11-11 Jun-En Ding , Chien-Chin Hsu , Chi-Hsiang Chu , Shuqiang Wang , Feng Liu

Human skeleton point clouds are commonly used to automatically classify and predict the behaviour of others. In this paper, we use a contrastive self-supervised learning method, SimCLR, to learn representations that capture the semantics of…

Computer Vision and Pattern Recognition · Computer Science 2022-11-11 Nico Lingg , Miguel Sarabia , Luca Zappella , Barry-John Theobald
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