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Motivation. Understanding the pan-cancer mutational landscape offers critical insights into the molecular mechanisms underlying tumorigenesis. While patient-level machine learning techniques have been widely employed to identify tumor…

Machine Learning · Computer Science 2025-08-29 Yifan Dou , Adam Khadre , Ruben C Petreaca , Golrokh Mirzaei

Despite the promising performance of convolutional neural networks (CNNs) in brain tumor diagnosis from magnetic resonance imaging (MRI), their integration into the clinical workflow has been limited. That is mainly due to the fact that the…

Image and Video Processing · Electrical Eng. & Systems 2024-11-04 Sara Ketabi , Matthias W. Wagner , Cynthia Hawkins , Uri Tabori , Birgit Betina Ertl-Wagner , Farzad Khalvati

Background Precise prediction of cancer types is vital for cancer diagnosis and therapy. Important cancer marker genes can be inferred through predictive model. Several studies have attempted to build machine learning models for this task…

Genomics · Quantitative Biology 2019-06-20 Milad Mostavi , Yu-Chiao Chiu , Yufei Huang , Yidong Chen

This paper proposes an efficient system for classifying cervical cancer cells using pre-trained convolutional neural networks (CNNs). We first fine-tune five pre-trained CNNs and minimize the overall cost of misclassification by…

Computer Vision and Pattern Recognition · Computer Science 2024-02-27 Ashfiqun Mustari , Rushmia Ahmed , Afsara Tasnim , Jakia Sultana Juthi , G M Shahariar

Breast cancer, the second leading cause of cancer-related deaths globally, accounts for a quarter of all cancer cases [1]. To lower this death rate, it is crucial to detect tumors early, as early-stage detection significantly improves…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Samia Saeed , Khuram Naveed

Due to cancer's complex nature and variable response to therapy, precision oncology informed by omics sequence analysis has become the current standard of care. However, the amount of data produced for each patients makes it difficult to…

Machine Learning · Computer Science 2023-10-30 Patrick J. Lawrence , Xia Ning

Contrastive learning has been proved to be a promising technique for image-level representation learning from unlabeled data. Many existing works have demonstrated improved results by applying contrastive learning in classification and…

Image and Video Processing · Electrical Eng. & Systems 2021-09-20 Dewen Zeng , John N. Kheir , Peng Zeng , Yiyu Shi

Large medical imaging datasets can be cheaply and quickly annotated with low-confidence, weak labels (e.g., radiological scores). Access to high-confidence labels, such as histology-based diagnoses, is rare and costly. Pretraining…

Computer Vision and Pattern Recognition · Computer Science 2023-09-20 Emma Sarfati , Alexandre Bône , Marc-Michel Rohé , Pietro Gori , Isabelle Bloch

The accurate diagnosis of pathological subtypes of lung cancer is of paramount importance for follow-up treatments and prognosis managements. Assessment methods utilizing deep learning technologies have introduced novel approaches for…

Image and Video Processing · Electrical Eng. & Systems 2024-07-19 Yuan Jin , Gege Ma , Geng Chen , Tianling Lyu , Jan Egger , Junhui Lyu , Shaoting Zhang , Wentao Zhu

Prognostic information at diagnosis has important implications for cancer treatment and monitoring. Although cancer staging, histopathological assessment, molecular features, and clinical variables can provide useful prognostic insights,…

Representation learning offers a conduit to elucidate distinctive features within the latent space and interpret the deep models. However, the randomness of lesion distribution and the complexity of low-quality factors in medical images…

Computer Vision and Pattern Recognition · Computer Science 2024-04-09 Qingshan Hou , Shuai Cheng , Peng Cao , Jinzhu Yang , Xiaoli Liu , Osmar R. Zaiane , Yih Chung Tham

Predicting the neural response to natural images in the visual cortex requires extracting relevant features from the images and relating those feature to the observed responses. In this work, we optimize the feature extraction in order to…

Computer Vision and Pattern Recognition · Computer Science 2024-10-10 Alex Mulrooney , Austin J. Brockmeier

Contrastive learning (CL) has become a powerful approach for learning representations from unlabeled images. However, existing CL methods focus predominantly on visual appearance features while neglecting topological characteristics (e.g.,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Guangyu Meng , Pengfei Gu , Peixian Liang , John P. Lalor , Erin Wolf Chambers , Danny Z. Chen

Computer-aided cancer survival risk prediction plays an important role in the timely treatment of patients. This is a challenging weakly supervised ordinal regression task associated with multiple clinical factors involved such as…

Machine Learning · Computer Science 2024-09-05 Zekang Yang , Hong Liu , Xiangdong Wang

Recently, contrastive learning (CL), a technique most prominently used in natural language and computer vision, has been used to train informative representation spaces for galaxy spectra and images in a self-supervised manner. Following…

Solar and Stellar Astrophysics · Physics 2024-11-19 Tobias Buck , Christian Schwarz

Since, cancer is curable when diagnosed at an early stage, lung cancer screening plays an important role in preventive care. Although both low dose computed tomography (LDCT) and computed tomography (CT) scans provide more medical…

Image and Video Processing · Electrical Eng. & Systems 2020-07-28 Worawate Ausawalaithong , Sanparith Marukatat , Arjaree Thirach , Theerawit Wilaiprasitporn

Brain tumor is a common and fatal form of cancer which affects both adults and children. The classification of brain tumors into different types is hence a crucial task, as it greatly influences the treatment that physicians will prescribe.…

Computer Vision and Pattern Recognition · Computer Science 2021-08-10 Tian Yu Liu , Jiashi Feng

Selective classification enables models to make predictions only when they are sufficiently confident, aiming to enhance safety and reliability, which is important in high-stakes scenarios. Previous methods mainly use deep neural networks…

Machine Learning · Computer Science 2024-06-10 Yu-Chang Wu , Shen-Huan Lyu , Haopu Shang , Xiangyu Wang , Chao Qian

Contrastive Learning (CL) performances as a rising approach to address the challenge of sparse and noisy recommendation data. Although having achieved promising results, most existing CL methods only perform either hand-crafted data or…

Information Retrieval · Computer Science 2023-11-22 Xiuyuan Qin , Huanhuan Yuan , Pengpeng Zhao , Junhua Fang , Fuzhen Zhuang , Guanfeng Liu , Victor Sheng

Spatial transcriptomics is a technology that captures gene expression levels at different spatial locations, widely used in tumor microenvironment analysis and molecular profiling of histopathology, providing valuable insights into…

Computer Vision and Pattern Recognition · Computer Science 2025-06-11 Junzhuo Liu , Markus Eckstein , Zhixiang Wang , Friedrich Feuerhake , Dorit Merhof
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