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Medical image classification is one of the most important tasks for computer-aided diagnosis. Deep learning models, particularly convolutional neural networks, have been successfully used for disease classification from medical images,…

Computer Vision and Pattern Recognition · Computer Science 2023-05-05 Md. Atik Ahamed , Jin Chen , Abdullah-Al-Zubaer Imran

In this paper, we present CLCC, a novel contrastive learning framework for color constancy. Contrastive learning has been applied for learning high-quality visual representations for image classification. One key aspect to yield useful…

Computer Vision and Pattern Recognition · Computer Science 2021-06-10 Yi-Chen Lo , Chia-Che Chang , Hsuan-Chao Chiu , Yu-Hao Huang , Chia-Ping Chen , Yu-Lin Chang , Kevin Jou

Dense prediction tasks such as segmentation and detection of pathological entities hold crucial clinical value in computational pathology workflows. However, obtaining dense annotations on large cohorts is usually tedious and expensive.…

Computer Vision and Pattern Recognition · Computer Science 2023-03-24 Jingwei Zhang , Saarthak Kapse , Ke Ma , Prateek Prasanna , Maria Vakalopoulou , Joel Saltz , Dimitris Samaras

Recently, contrastive learning (CL) has emerged as a successful method for unsupervised graph representation learning. Most graph CL methods first perform stochastic augmentation on the input graph to obtain two graph views and maximize the…

Machine Learning · Computer Science 2021-03-01 Yanqiao Zhu , Yichen Xu , Feng Yu , Qiang Liu , Shu Wu , Liang Wang

The application of natural language processing (NLP) to cancer pathology reports has been focused on detecting cancer cases, largely ignoring precancerous cases. Improving the characterization of precancerous adenomas assists in developing…

Machine Learning · Computer Science 2022-12-13 Yizhen Zhong , Jiajie Xiao , Thomas Vetterli , Mahan Matin , Ellen Loo , Jimmy Lin , Richard Bourgon , Ofer Shapira

With the increased affordability and availability of whole-genome sequencing, large-scale and high-throughput gene expression is widely used to characterize diseases, including cancers. However, establishing specificity in cancer diagnosis…

Machine Learning · Statistics 2018-12-21 Xi Chen , Jin Xie , Qingcong Yuan

Risk stratification (characterization) of tumors from radiology images can be more accurate and faster with computer-aided diagnosis (CAD) tools. Tumor characterization through such tools can also enable non-invasive cancer staging,…

Computer Vision and Pattern Recognition · Computer Science 2019-01-21 Sarfaraz Hussein , Pujan Kandel , Candice W. Bolan , Michael B. Wallace , Ulas Bagci

Representation learning has significantly been developed with the advance of contrastive learning methods. Most of those methods have benefited from various data augmentations that are carefully designated to maintain their identities so…

Computer Vision and Pattern Recognition · Computer Science 2022-01-24 Xiao Wang , Guo-Jun Qi

Machine learning can precisely identify different cancer tumors at any stage by classifying cancerous and healthy samples based on their genomic profile. We have developed novel methods of MLAC (Machine Learning Against Cancer) achieving…

Genomics · Quantitative Biology 2020-09-15 Arash Hooshmand

Digital pathological analysis is run as the main examination used for cancer diagnosis. Recently, deep learning-driven feature extraction from pathology images is able to detect genetic variations and tumor environment, but few studies…

Computer Vision and Pattern Recognition · Computer Science 2022-04-28 Haojie Huang , Gongming Zhou , Xuejun Liu , Lei Deng , Chen Wu , Dachuan Zhang , Hui Liu

In this paper, we describe a dataset relating to cellular and physical conditions of patients who are operated upon to remove colorectal tumours. This data provides a unique insight into immunological status at the point of tumour removal,…

Machine Learning · Computer Science 2016-11-17 Chris Roadknight , Uwe Aickelin , Guoping Qiu , John Scholefield , Lindy Durrant

Convolutional neural networks (CNNs) have shown great promise in improving computer aided detection (CADe). From classifying tumors found via mammography as benign or malignant to automated detection of colorectal polyps in CT colonography,…

Computer Vision and Pattern Recognition · Computer Science 2019-07-30 Hunter Park , Connor Monahan

Contrastive learning (CL) methods effectively learn data representations in a self-supervision manner, where the encoder contrasts each positive sample over multiple negative samples via a one-vs-many softmax cross-entropy loss. By…

Machine Learning · Computer Science 2023-08-16 Huangjie Zheng , Xu Chen , Jiangchao Yao , Hongxia Yang , Chunyuan Li , Ya Zhang , Hao Zhang , Ivor Tsang , Jingren Zhou , Mingyuan Zhou

Contrastive learning is a representation learning method performed by contrasting a sample to other similar samples so that they are brought closely together, forming clusters in the feature space. The learning process is typically…

Machine Learning · Computer Science 2022-09-28 Valentino Vito , Lim Yohanes Stefanus

This paper presents Prototypical Contrastive Learning (PCL), an unsupervised representation learning method that addresses the fundamental limitations of instance-wise contrastive learning. PCL not only learns low-level features for the…

Computer Vision and Pattern Recognition · Computer Science 2021-03-31 Junnan Li , Pan Zhou , Caiming Xiong , Steven C. H. Hoi

The burgeoning discipline of computational pathology shows promise in harnessing whole slide images (WSIs) to quantify morphological heterogeneity and develop objective prognostic modes for human cancers. However, progress is impeded by the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-20 Chao Tu , Kun Huang , Jie Zhang , Qianjin Feng , Yu Zhang , Zhenyuan Ning

Medical image segmentation is a critical yet challenging task, primarily due to the difficulty of obtaining extensive datasets of high-quality, expert-annotated images. Contrastive learning presents a potential but still problematic…

Computer Vision and Pattern Recognition · Computer Science 2025-04-22 Shuang Zeng , Lei Zhu , Xinliang Zhang , Hangzhou He , Yanye Lu

In this work, we present Multi-Level Contrastive Learning for Dense Prediction Task (MCL), an efficient self-supervised method for learning region-level feature representation for dense prediction tasks. Our method is motivated by the three…

Computer Vision and Pattern Recognition · Computer Science 2023-04-05 Qiushan Guo , Yizhou Yu , Yi Jiang , Jiannan Wu , Zehuan Yuan , Ping Luo

Effective protein representation learning is crucial for predicting protein functions. Traditional methods often pretrain protein language models on large, unlabeled amino acid sequences, followed by finetuning on labeled data. While…

Biomolecules · Quantitative Biology 2024-09-05 Jiangbin Zheng , Stan Z. Li

Detectingandsegmentingobjectswithinwholeslideimagesis essential in computational pathology workflow. Self-supervised learning (SSL) is appealing to such annotation-heavy tasks. Despite the extensive benchmarks in natural images for dense…

Computer Vision and Pattern Recognition · Computer Science 2022-07-15 Jiawei Yang , Hanbo Chen , Yuan Liang , Junzhou Huang , Lei He , Jianhua Yao