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Incorporating the inherent heterogeneity of living systems into models of active nematics is essential to provide a more realistic description of biological processes such as bacterial growth, cell dynamics and tissue development.…

Soft Condensed Matter · Physics 2024-11-06 Alexander J. H. Houston , Nigel J. Mottram

Recent experiments and numerical studies have drawn attention to the dynamics of active nematics. Two-dimensional active nematics flow spontaneously and exhibit spatiotemporal chaotic flows with proliferation of topological defects in the…

Soft Condensed Matter · Physics 2020-07-08 Farzan Vafa , Mark J. Bowick , M. Cristina Marchetti , Boris I. Shraiman

Engineering synthetic materials that mimic the remarkable complexity of living organisms is a fundamental challenge in science and technology. We study the spatiotemporal patterns that emerge when an active nematicfilm of microtubules and…

Using novel micro-printing techniques, we develop a versatile experimental setup that allows us to study how lateral confinement tames the active flows and defect properties of the microtubule/kinesin active nematic system. We demonstrate…

Topological defects are at the root of the large-scale organization of liquid crystals. In two-dimensional active nematics, two classes of topological defects of charges $\pm 1/2$ are known to play a major role due to active stresses.…

Soft Condensed Matter · Physics 2022-04-08 Louis Brézin , Thomas Risler , Jean-François Joanny

We study the dynamics of active nematic films on a substrate driven by active flows with or without the incompressible constraint.Through simulations and theoretical analysis, we show that arch patterns are stable in the compressible case,…

Soft Condensed Matter · Physics 2022-11-30 Supavit Pokawanvit , Zhitao Chen , Zhihong You , Luiza Angheluta , M. Cristina Marchetti , Mark J. Bowick

We study the active flow around isolated defects and the self-propulsion velocity of $+1/2$ defects in an active nematic film with both viscous dissipation (with viscosity $\eta$) and frictional damping $\Gamma$ with a substrate. The…

Soft Condensed Matter · Physics 2022-01-28 Jonas Rønning , M. Cristina Marchetti , Mark J. Bowick , Luiza Angheluta

Active nematic fluids confined in narrow channels generate spontaneous flows when the activity is sufficiently intense. Recently, it was shown that if the molecular anchoring at the channel walls is conflicting flows are initiated even in…

Soft Condensed Matter · Physics 2021-11-02 C. Rorai , F. Toschi , I. Pagonabarraga

We consider the hydrodynamic theory of an active fluid of self-propelled particles with nematic aligning interactions. This class of materials has polar symmetry at the microscopic level, but forms macrostates of nematic symmetry. We…

Soft Condensed Matter · Physics 2012-04-17 Aparna Baskaran , M. Cristina Marchetti

The topological properties of many materials are central to their behavior, with the dynamics of topological defects being particularly important to intrinsically out-of-equilibrium, active materials. In this paper, local manipulation of…

Soft Condensed Matter · Physics 2019-11-01 David P. Rivas , Tyler N. Shendruk , Robert R. Henry , Daniel H. Reich , Robert L. Leheny

With exquisite precision and reproducibility, cells orchestrate the cooperative action of thousands of nanometer-sized molecular motors to carry out mechanical tasks at much larger length scales, such as cell motility, division and…

Soft Condensed Matter · Physics 2013-01-08 Tim Sanchez , Daniel T. N. Chen , Stephen J. DeCamp , Michael Heymann , Zvonimir Dogic

Active fluids display spontaneous turbulent-like flows known as active turbulence. Recent work revealed that these flows have universal features, independent of the material properties and of the presence of topological defects. However,…

Soft Condensed Matter · Physics 2026-03-19 Ido Lavi , Ricard Alert , Jean-François Joanny , Jaume Casademunt

Topological defects are increasingly being identified in various biological systems, where their characteristic flow fields and stress patterns are associated with continuous active stress generation by biological entities. Here, using…

Soft Condensed Matter · Physics 2022-11-09 Lasse Bonn , Aleksandra Ardaseva , Romain Mueller , Tyler N. Shendruk , Amin Doostmohammadi

We provide a minimal model for an active nematic film in contact with both a solid substrate and a passive isotropic fluid, and explore its dynamics in one and two dimensions using a combination of hybrid Lattice Boltzmann simulations and…

Soft Condensed Matter · Physics 2017-02-16 Matthew L. Blow , Marco Aqil , Benno Liebchen , Davide Marenduzzo

Active nematics are the nonequilibrium analog of passive liquid crystals in which anisotropic units consume free energy to drive emergent behavior. Similar to liquid crystal (LC) molecules in displays, ordering and dynamics in active…

Quantitative Methods · Quantitative Biology 2022-10-10 Japinder Nijjer , Mrityunjay Kothari , Changhao Li , Thomas Henzel , Qiuting Zhang , Jung-Shen B. Tai , Shuang Zhou , Sulin Zhang , Tal Cohen , Jing Yan

Recent studies have shown that packings of cells, both eukaryotic cellular tissues and growing or swarming bacterial colonies, can often be understood as active nematic fluids. A key property of volume-conserving active nematic model…

Soft Condensed Matter · Physics 2022-05-12 Fabian Jan Schwarzendahl , Daniel A. Beller

Cell monolayers are a central model system to tissue biophysics. In vivo, epithelial tissues are curved on the scale of microns, and curvature's role in the onset of spontaneous tissue flows is still not well-understood. Here, we present a…

Biological Physics · Physics 2022-09-21 Samuel Bell , Shao-Zhen Lin , Jean-François Rupprecht , Jacques Prost

We study emergent dynamics in a viscous drop subject to interfacial nematic activity. Using hydrodynamic simulations, we show how the interplay of nematodynamics, activity-driven flows and surface deformations gives rise to a sequence of…

Soft Condensed Matter · Physics 2024-04-19 Mohammadhossein Firouznia , David Saintillan

We consider a phase-separating mixture of active and passive fluids and explore morphological asymmetries of the emerging dominantly bicontinous dynamic emulsion. Two-dimensional numerical simulations reveal that the geometric and…

Soft Condensed Matter · Physics 2026-01-22 Rainer Backofen , Axel Voigt

Active nematics are out-of-equilibrium systems in which energy injection at the microscale drives emergent collective behaviors, from spontaneous flows to active turbulence. While the dynamics of these systems have been extensively studied,…

Soft Condensed Matter · Physics 2025-04-15 Ahmet Umut Akduman , Yusuf Sariyar , Giuseppe Negro , Livio Nicola Carenza
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