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How can a collection of motile cells, each generating contractile nematic stresses in isolation, become an extensile nematic at the tissue-level? Understanding this seemingly contradictory experimental observation, which occurs irrespective…

Soft Condensed Matter · Physics 2022-02-21 Andrew Killeen , Thibault Bertrand , Chiu Fan Lee

We review recent advances in the design, synthesis, and modeling of active fluids. Active fluids have been at the center of many technological innovations and theoretical advances over the past two decades. Research on this new class of…

Soft Condensed Matter · Physics 2023-02-02 Ilham Essafri , Bappa Ghosh , Caroline Desgranges , Jerome Delhommelle

We report curling self-propulsion in aqueous emulsions of common mesogenic compounds. Nematic liquid crystal droplets self-propel in a surfactant solution with concentrations above the critical micelle concentration while undergoing…

Soft Condensed Matter · Physics 2019-10-15 Carsten Krüger , Gunnar Klös , Christian Bahr , Corinna C. Maass

A paradigm for internally driven matter is the active nematic liquid crystal, whereby the equations of a conventional nematic are supplemented by a minimal active stress that violates time reversal symmetry. In practice, active fluids may…

Soft Condensed Matter · Physics 2015-12-15 E. J. Hemingway , A. Maitra , S. Banerjee , M. C. Marchetti , S. Ramaswamy , S. M. Fielding , M. E. Cates

We study the flow behavior and unjamming transition in dense assemblies of actively deforming particles that periodically change size, a process that we refer to as breathing. Using extensive molecular dynamics simulations and a…

Soft Condensed Matter · Physics 2025-05-21 Sayantan Ghosh , Magali Le Goff , Pinaki Chaudhuri , Kirsten Martens

Biological cells can actively tune their intracellular architecture according to their overall shape. Here we explore the rheological implication of such coupling in a minimal model of a dense cellular material where each cell exerts an…

Soft Condensed Matter · Physics 2022-04-13 Shao-Zhen Lin , Matthias Merkel , Jean-François Rupprecht

There is increasing evidence that mammalian cells not only crawl on substrates but can also swim in fluids. To elucidate the mechanisms of the onset of motility of cells in suspension, a model which couples actin and myosin kinetics to…

Biological Physics · Physics 2019-09-18 Alexander Farutin , Jocelyn Etienne , Chaouqi Misbah , Pierre Recho

Active nematics are microscopically driven liquid crystals that exhibit dynamical steady states characterized by the creation and annihilation of topological defects. Motivated by experimental realizations of such systems made of biopolymer…

Soft Condensed Matter · Physics 2018-09-05 Abhijeet Joshi , Elias Putzig , Aparna Baskaran , Michael Hagan

Active nematics are fluids in which the components have nematic symmetry and are driven out of equilibrium due to the microscopic generation of an active stress. When the active stress is high, it drives flows in the nematic and can lead to…

Soft Condensed Matter · Physics 2025-11-10 Daniel J. G. Pearce , Berta Martínez-Prat , Jordi Ignés-Mullol , Francesc Sagués

Active (i.e., self-propelled or swimming) particles moving through an isotropic fluid exhibit conventional diffusive behavior. We report anomalous diffusion of an active particle moving in an anisotropic, nematic background. Whilst the…

Soft Condensed Matter · Physics 2016-06-22 John Toner , Hartmut Löwen , Henricus H. Wensink

Animal morphogenesis often involves significant shape changes of epithelial tissue sheets. Great progress has been made in understanding the underlying cellular driving forces and their coordination through biomechanical feedback loops.…

Soft Condensed Matter · Physics 2024-09-23 Nikolas H. Claussen , Fridtjof Brauns

There is now growing evidence of the emergence and biological functionality of liquid crystal features, including nematic order and topological defects, in cellular tissues. However, how such features that intrinsically rely on particle…

Soft Condensed Matter · Physics 2019-02-06 Romain Mueller , Julia Yeomans , Amin Doostmohammadi

The hydrodynamics of smectic films at an air-water interface is discussed, with particular focus on the viscous response of the film under flow normal to the layers. The corrections to the response functions of the smectic phase, arising…

Soft Condensed Matter · Physics 2007-05-23 Shilpa Jain , David R. Nelson

Biological tissues exhibit diverse mechanical and rheological behaviors during morphogenesis. While much is known about tissue phase transitions controlled by structural order and cell mechanics, key questions regarding how tissue-scale…

Soft Condensed Matter · Physics 2026-04-29 Pengyu Yu , Fridtjof Brauns , M. Cristina Marchetti

Using a minimal continuum model, we investigate the interplay between circular confinement and substrate friction in active nematics. Upon increasing the friction from low to high, we observe a dynamical phase transition from a circulating…

Soft Condensed Matter · Physics 2023-10-27 Cody D. Schimming , C. J. O. Reichhardt , C. Reichhardt

Catalytically active colloids maintain non-equilibrium conditions in which they produce and deplete chemicals and hence effectively act as sources and sinks of molecules. While individual colloids that are symmetrically coated do not…

Soft Condensed Matter · Physics 2015-06-11 Rodrigo Soto , Ramin Golestanian

When considering flows in biological membranes, they are usually treated as flat, though more often than not, they are curved surfaces, even extremely curved, as in the case of the endoplasmic reticulum. Here, we study the topological…

Fluid Dynamics · Physics 2021-05-27 Rickmoy Samanta , Naomi Oppenheimer

We study the structure and dynamics of the interface separating a passive fluid from a microtubule-based active fluid. Turbulent-like active flows power giant interfacial fluctuations, which exhibit pronounced asymmetry between regions of…

Inspired by recent experiments of cells accumulating on anisotropic substrates, we study a two-dimensional, compressible, isotropic, active fluid in the presence of anisotropic friction. We find that regions of anisotropic friction that are…

Soft Condensed Matter · Physics 2026-03-04 Cody D. Schimming , Brian A. Camley

Living materials at different length scales manifest active nematic features such as orientational order, nematic topological defects, and active nematic turbulence. Using numerical simulations we investigate the impact of fluid inertia on…

Soft Condensed Matter · Physics 2022-08-10 Roozbeh Saghatchi , Mehmet Yildiz , Amin Doostmohammadi
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