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In this work, we develop and analyze adaptive feedback control strategies to stabilize and confine a nanoparticle at the unstable intensity minimum of an optical double-well potential. The resulting stochastic optimal control problem for a…

High-density microfluidics is becoming an important experimental platform for studying complex biological systems such as synthetic gene regulatory networks, molecular biocomputating of engineered cells, distributing rapid point-of-care…

Biological Physics · Physics 2021-07-21 Sankar Raju Narayanasamy , Ramakrishna Vasireddi , Hoi-Ying Holman

Synthetic biology is an interdisciplinary field aiming to design biochemical systems with desired behaviors. To this end, molecular controllers have been developed which, when embedded into a pre-existing ambient biochemical network,…

Molecular Networks · Quantitative Biology 2019-08-29 Tomislav Plesa , Guy-Bart Stan , Thomas E. Ouldridge , Wooli Bae

Fluidic iontronics offer a unique capability for emulating the chemical processes found in neurons. We extract multiple distinct chemically regulated synaptic features from an experimentally accessible conical microfluidic channel carrying…

Soft Condensed Matter · Physics 2026-02-13 T. M. Kamsma , M. S. Klop , W. Q. Boon , C. Spitoni , B. Rueckauer , R. van Roij

In vitro neuronal culture is an important research platform in cellular and network neuroscience. However, neurons cultured on a homogeneous scaffold form dense, randomly connected networks and display excessively synchronized activity;…

Neurons and Cognition · Quantitative Biology 2024-05-30 Hakuba Murota , Hideaki Yamamoto , Nobuaki Monma , Shigeo Sato , Ayumi Hirano-Iwata

We explore the influence of a block of excitable units on the existence and behavior of chimera states in a nonlocally coupled ring-network of FitzHugh-Nagumo elements. The FitzHugh-Nagumo system, a paradigmatic model in many fields from…

Pattern Formation and Solitons · Physics 2016-03-02 Thomas Isele , Johanne Hizanidis , Astero Provata , Philipp Hövel

Convergence extension, the simultaneous elongation of tissue along one axis while narrowing along a perpendicular axis, occurs during embryonic development. A fundamental process that contributes to shaping the organism, it happens in many…

Soft Condensed Matter · Physics 2023-03-06 Aondoyima Ioratim-Uba , Tanniemola B. Liverpool , Silke Henkes

We demonstrate a fully cryogenic microwave feedback network composed of modular superconducting devices connected by transmission lines and designed to control a mechanical oscillator coupled to one of the devices. The network features an…

We consider a nonlinear reaction diffusion system of parabolic type known as the monodomain equations, which model the interaction of the electric current in a cell. Together with the FitzHugh-Nagumo model for the nonlinearity they…

Optimization and Control · Mathematics 2021-01-27 Thomas Berger , Tobias Breiten , Marc Puche , Timo Reis

Reversible bipolar nano-switches that can be set and read electronically in a solid-state two-terminal device are very promising for applications. We have performed molecular-dynamics simulations that mimic systems with oxygen vacancies…

Mesoscale and Nanoscale Physics · Physics 2015-05-20 S. E. Savel'ev , A. S. Alexandrov , A. M. Bratkovsky , R. Stanley Williams

Feedback control plays a crucial role in improving system accuracy and stability for a variety of scientific and engineering applications. Here, we theoretically and experimentally investigate the implementation of feedback control in…

Optics · Physics 2024-03-15 David J. Moss

Molecular communication (MC) enables cooperation of spatially dispersed molecular robots through the feedback control mediated by diffusing signal molecules. However, conventional analysis frameworks for the MC channels mostly consider the…

Systems and Control · Electrical Eng. & Systems 2025-08-11 Taishi Kotsuka , Yutaka Hori

Semiconductor lasers are notoriously sensitive to optical feedback, and their dynamics and coherence can be significantly modified through optical reinjection. We concentrate on the dynamical properties of a very small (i.e., microscale)…

Active materials with distinctive nonequilibrium properties have diverse materials science applications. Active systems are common in living matter, such as the filament network in the cell that is activated by molecular motors, and in…

Soft Condensed Matter · Physics 2022-09-14 Lilan Qiao , Raymond Kapral

Inspired by the path followed by Matthias Ballauff over the past 20 years, the development of thermosensitive core-shell microgel structures is reviewed. Different chemical approaches, from hard nanoparticle cores to double…

Soft Condensed Matter · Physics 2020-11-17 Julian Oberdisse , Thomas Hellweg

Using the model of a FitzHugh-Nagumo system in the excitable regime we investigate the influence of time-delayed feedback on noise-induced chimera states in a network with nonlocal coupling, i.e., coherence resonance chimeras. It is shown…

Adaptation and Self-Organizing Systems · Physics 2018-04-05 Anna Zakharova , Nadezhda Semenova , Vadim Anishchenko , Eckehard Schöll

This work presents the mathematical modeling and numerical investigation of a thermo-controlled Micro-Electro-Mechanical System (MEMS) obtained by coupling an HP memristor with mechanical and electrical resonators. Using the linear drift HP…

Chaotic Dynamics · Physics 2026-05-29 N. G. Koudafokê , Thierry Njougouo , Hilda A. Cerdeira , C. H. Miwadinou

Biomolecular feedback systems are now a central application area of interest within control theory. While classical control techniques provide invaluable insight into the function and design of both natural and synthetic biomolecular…

Systems and Control · Electrical Eng. & Systems 2019-11-15 Noah Olsman , Fulvio Forni

An electronic circuit device, inspired on the FitzHugh-Nagumo model of neuronal excitability, was constructed and shown to operate with characteristics compatible with those of biological sensory neurons. The nonlinear dynamical model of…

Constructing electronic models of neurons has several applications including reproducing dynamics of biological neurons and their networks and neuroprosthetics. In the brain, most neurons themselves are in a non-oscillatory mode, and brain…

Adaptation and Self-Organizing Systems · Physics 2023-05-09 Nikita M. Egorov , Marina V. Sysoeva , Vladimir I. Ponomarenko , Ilya V. Sysoev