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Graph representation learning (GRL) has emerged as an effective technique for modeling graph-structured data. When modeling heterogeneity and dynamics in real-world complex networks, GRL methods designed for complex heterogeneous temporal…

Social and Information Networks · Computer Science 2026-05-19 Huan Liu , Pengfei Jiao , Mengzhou Gao , Chaochao Chen , Di Jin

The theoretical investigation of gas adsorption, storage, separation, diffusion and related transport processes in porous materials relies on a detailed knowledge of the potential energy surface of molecules in a stationary environment. In…

Chemical Physics · Physics 2025-01-30 Johannes K. Krondorfer , Christian W. Binder , Andreas W. Hauser

Graphs are ubiquitous data structures for representing interactions between entities. With an emphasis on the use of graphs to represent chemical molecules, we explore the task of learning to generate graphs that conform to a distribution…

Machine Learning · Computer Science 2019-03-08 Qi Liu , Miltiadis Allamanis , Marc Brockschmidt , Alexander L. Gaunt

The open-world test dataset is often mixed with out-of-distribution (OOD) samples, where the deployed models will struggle to make accurate predictions. Traditional detection methods need to trade off OOD detection and in-distribution (ID)…

Machine Learning · Computer Science 2024-04-25 Xu Shen , Yili Wang , Kaixiong Zhou , Shirui Pan , Xin Wang

Heterogeneous catalysis is an example of a complex materials function, governed by an intricate interplay of several processes, e.g., the different surface chemical reactions, and the dynamic re-structuring of the catalyst material at…

Graph data often exhibits complex geometric heterogeneity, where structures with varying local curvature, such as tree-like hierarchies and dense communities, coexist within a single network. Existing geometric GNNs, which embed graphs into…

Machine Learning · Computer Science 2026-01-21 Xudong Wang , Chris Ding , Tongxin Li , Jicong Fan

Representation learning has become an effective technique utilized by electronic design automation (EDA) algorithms, which leverage the natural representation of workflow elements as images, grids, and graphs. By addressing challenges…

Machine Learning · Computer Science 2025-05-06 Pratik Shrestha , Saran Phatharodom , Alec Aversa , David Blankenship , Zhengfeng Wu , Ioannis Savidis

Computational high-throughput studies, especially in research on high-entropy materials and catalysts, are hampered by high-dimensional composition spaces and myriad structural microstates. They present bottlenecks to the conventional use…

Materials Science · Physics 2024-03-18 Christian M. Clausen , Jan Rossmeisl , Zachary W. Ulissi

To be able to predict a molecular graph structure ($W$) given a 2D image of a chemical compound ($U$) is a challenging problem in machine learning. We are interested to learn $f: U \rightarrow W$ where we have a fully mediating…

Machine Learning · Computer Science 2022-01-13 Martijn Oldenhof , Adam Arany , Yves Moreau , Jaak Simm

Quantifying how hard it is to build a molecular graph matters for biosignature detection, chemical complexity, and cheminformatics. We present an exact, scalable algorithm to compute the molecular assembly index (MA) which prioritizes the…

Data Structures and Algorithms · Computer Science 2025-08-19 Ian Seet , Keith Y. Patarroyo , Gage Siebert , Sara I. Walker , Leroy Cronin

Solving Algebra Problems with Geometry Diagrams (APGDs) is still a challenging problem because diagram processing is not studied as intensively as language processing. To work against this challenge, this paper proposes a hologram reasoning…

Artificial Intelligence · Computer Science 2024-08-21 Litian Huang , Xinguo Yu , Feng Xiong , Bin He , Shengbing Tang , Jiawen Fu

Machine learning (ML) and deep learning (DL) techniques have gained significant attention as reduced order models (ROMs) to computationally expensive structural analysis methods, such as finite element analysis (FEA). Graph neural network…

Machine Learning · Computer Science 2023-09-25 Yuecheng Cai , Jasmin Jelovica

Graph neural networks (GNNs) are proven effective in extracting complex node and structural information from graph data. While current GNNs perform well in node classification tasks within in-distribution (ID) settings, real-world scenarios…

Machine Learning · Computer Science 2025-05-08 Tao Yin , Chen Zhao , Xiaoyan Liu , Minglai Shao

Automotive engineering development increasingly relies on heterogeneous 3D data, including finite element (FE) models, body-in-white (BiW) representations, CAD geometry, and CFD meshes. At the same time, engineering teams face growing…

In the field of signal processing on graphs, graph filters play a crucial role in processing the spectrum of graph signals. This paper proposes two different strategies for designing autoregressive moving average (ARMA) graph filters on…

Signal Processing · Electrical Eng. & Systems 2018-07-02 Jiani Liu , Elvin Isufi , Geert Leus

Covalent organic frameworks (COFs) are promising photocatalysts for solar hydrogen production, yet the most electronically favorable linkages, imines, hydrolyze rapidly in water, creating a stability--activity trade-off that limits…

Chemical Physics · Physics 2026-03-06 Iman Peivaste , Nicolas D. Boscher , Ahmed Makradi , Salim Belouettar

In genome-scale constraint-based metabolic models, gene deletion strategies are essential for achieving growth-coupled production, where cell growth and target metabolite synthesis occur simultaneously. Despite the inherently networked…

Quantitative Methods · Quantitative Biology 2026-04-10 Ziwei Yang , Takeyuki Tamura

Existing LLM-driven knowledge graph (KG) construction methods predominantly employ stateless batch processing pipelines, exhibiting structural deficiencies in cross-chunk semantic relation capture, entity disambiguation, and construction…

Artificial Intelligence · Computer Science 2026-05-19 Chengrui Han , Zesheng Cheng

The integration of multi-omics single-cell data remains challenging due to high-dimensionality and complex inter-modality relationships. To address this, we introduce MoRE-GNN (Multi-omics Relational Edge Graph Neural Network), a…

Machine Learning · Computer Science 2025-10-09 Zhiyu Wang , Sonia Koszut , Pietro Liò , Francesco Ceccarelli

International initiatives such as METABRIC (Molecular Taxonomy of Breast Cancer International Consortium) have collected several multigenomic and clinical data sets to identify the undergoing molecular processes taking place throughout the…

Machine Learning · Computer Science 2022-11-29 Teodora Reu
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