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The classification of histopathological images is of great value in both cancer diagnosis and pathological studies. However, multiple reasons, such as variations caused by magnification factors and class imbalance, make it a challenging…

Computer Vision and Pattern Recognition · Computer Science 2022-09-01 Yibao Sun , Xingru Huang , Yaqi Wang , Huiyu Zhou , Qianni Zhang

We put forward an adaptive alpha (Type I Error) that decreases as the information grows, for hypothesis tests in which nested linear models are compared. A less elaborate adaptation was already presented in \citet{PP2014} for comparing…

Methodology · Statistics 2021-01-06 D. Vélez , M. E. Pérez , L. R. Pericchi

The recent surge of foundation models in computer vision and natural language processing opens up perspectives in utilizing multi-modal clinical data to train large models with strong generalizability. Yet pathological image datasets often…

Computer Vision and Pattern Recognition · Computer Science 2023-07-28 Yunkun Zhang , Jin Gao , Mu Zhou , Xiaosong Wang , Yu Qiao , Shaoting Zhang , Dequan Wang

Human nail diseases are gradually observed over all age groups, especially among older individuals, often going ignored until they become severe. Early detection and accurate diagnosis of such conditions are important because they sometimes…

Computer Vision and Pattern Recognition · Computer Science 2026-02-05 Farzia Hossain , Samanta Ghosh , Shahida Begum , B. M. Shahria Alam , Mohammad Tahmid Noor , Md Parvez Mia , Nishat Tasnim Niloy

Technology aided platforms provide reliable tools in almost every field these days. These tools being supported by computational power are significant for applications that need sensitive and precise data analysis. One such important…

Computer Vision and Pattern Recognition · Computer Science 2020-03-16 Muhammad Ali Farooq , Muhammad Aatif Mobeen Azhar , Rana Hammad Raza

Multi-scale problems, where variables of interest evolve in different time-scales and live in different state-spaces, can be found in many fields of science. Here, we introduce a new recursive methodology for Bayesian inference that aims at…

Computation · Statistics 2024-07-08 Sara Pérez-Vieites , Harold Molina-Bulla , Joaquin Miguez

Mass spectrometry provides a high-throughput way to identify proteins in biological samples. In a typical experiment, proteins in a sample are first broken into their constituent peptides. The resulting mixture of peptides is then subjected…

Applications · Statistics 2010-11-10 Qunhua Li , Michael J. MacCoss , Matthew Stephens

Quantifying the uncertainty in predictive models is critical for establishing trust and enabling risk-informed decision making for personalized medicine. In contrast to one-size-fits-all approaches that seek to mitigate risk at the…

Computational Engineering, Finance, and Science · Computer Science 2025-05-15 Graham Pash , Umberto Villa , David A. Hormuth , Thomas E. Yankeelov , Karen Willcox

Screening mammograms is the gold standard for detecting breast cancer early. While a good amount of work has been performed on mammography image classification, especially with deep neural networks, there has not been much exploration into…

Machine Learning · Computer Science 2020-08-14 Anika Tabassum , Naimul Khan

Online and AI-based symptom checkers are applications that assist medical laypeople in diagnosing their symptoms and determining which course of action to take. When evaluating these tools, previous studies primarily used an approach…

Human-Computer Interaction · Computer Science 2025-06-30 Marvin Kopka , Markus A. Feufel

Often the rows (cases, objects) of a dataset have weights. For instance, the weight of a case may reflect the number of times it has been observed, or its reliability. For analyzing such data many rowwise weighted techniques are available,…

Computation · Statistics 2024-07-08 Peter J. Rousseeuw

Remote sensing scene classification aims to assign a specific semantic label to a remote sensing image. Recently, convolutional neural networks have greatly improved the performance of remote sensing scene classification. However, some…

Computer Vision and Pattern Recognition · Computer Science 2022-05-24 Zhang Yue , Zheng Xiangtao , Lu Xiaoqiang

Anomaly detection has been widely studied in the context of industrial defect inspection, with numerous methods developed to tackle a range of challenges. In digital pathology, anomaly detection holds significant potential for applications…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Can Cui , Xindong Zheng , Ruining Deng , Quan Liu , Tianyuan Yao , Keith T Wilson , Lori A Coburn , Bennett A Landman , Haichun Yang , Yaohong Wang , Yuankai Huo

Identifying differences in networks has become a canonical problem in many biological applications. Here, we focus on testing whether two Gaussian graphical models are the same. Existing methods try to accomplish this goal by either…

Methodology · Statistics 2019-10-01 Sen Zhao , Stephen Ottinger , Suzanne Peck , Christine Mac Donald , Ali Shojaie

Analyzing microscopy images to extract biological object properties (e.g., their morphological organization, temporal dynamics, and population density) is fundamental to various biomedical research. Yet conducting this manually is costly…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Xiaofei Hui , Haoxuan Qu , Hossein Rahmani , Shuohong Wang , Jeff W. Lichtman , Jun Liu

We consider the problem of landmark matching between two unlabelled point sets, in particular where the number of points in each cloud may differ, and where points in each cloud may not have a corresponding match. We invoke a Bayesian…

Methodology · Statistics 2022-06-01 Jessica E. Forsyth , Ali H. Al-Anbaki , Berenika Plusa , Simon L. Cotter

Combining multiple machine learning models has long been a technique for enhancing performance, particularly in distributed settings. Traditional approaches, such as model ensembles, work well, but are expensive in terms of memory and…

Machine Learning · Computer Science 2024-12-23 Albert Manuel Orozco Camacho , Stefan Horoi , Guy Wolf , Eugene Belilovsky

The rising global prevalence of skin conditions, some of which can escalate to life-threatening stages if not timely diagnosed and treated, presents a significant healthcare challenge. This issue is particularly acute in remote areas where…

Computer Vision and Pattern Recognition · Computer Science 2024-02-19 Mahapara Khurshid , Mayank Vatsa , Richa Singh

Segmentation from renal pathological images is a key step in automatic analyzing the renal histological characteristics. However, the performance of models varies significantly in different types of stained datasets due to the appearance…

Image and Video Processing · Electrical Eng. & Systems 2020-02-21 Ke Mei , Chuang Zhu , Lei Jiang , Jun Liu , Yuanyuan Qiao

Multiplexed immunofluorescence provides an unprecedented opportunity for studying specific cell-to-cell and cell microenvironment interactions. We employ graph neural networks to combine features obtained from tissue morphology with…