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Understanding cell identity and function through single-cell level sequencing data remains a key challenge in computational biology. We present a novel framework that leverages gene-specific textual annotations from the NCBI Gene database…

Genomics · Quantitative Biology 2025-05-14 Douglas Jiang , Zilin Dai , Luxuan Zhang , Qiyi Yu , Haoqi Sun , Feng Tian

Sequential sentence classification (SSC) in scientific publications is crucial for supporting downstream tasks such as fine-grained information retrieval and extractive summarization. However, current SSC methods are constrained by model…

Computation and Language · Computer Science 2024-12-02 Mengfei Lan , Lecheng Zheng , Shufan Ming , Halil Kilicoglu

3D deep learning is a growing field of interest due to the vast amount of information stored in 3D formats. Triangular meshes are an efficient representation for irregular, non-uniform 3D objects. However, meshes are often challenging to…

Computer Vision and Pattern Recognition · Computer Science 2022-12-23 Ayaan Haque , Hankyu Moon , Heng Hao , Sima Didari , Jae Oh Woo , Patrick Bangert

Recently, contrastive learning has been shown to be effective in improving pre-trained language models (PLM) to derive high-quality sentence representations. It aims to pull close positive examples to enhance the alignment while push apart…

Computation and Language · Computer Science 2022-05-03 Kun Zhou , Beichen Zhang , Wayne Xin Zhao , Ji-Rong Wen

Since the meaning representations are detailed and accurate annotations which express fine-grained sequence-level semtantics, it is usually hard to train discriminative semantic parsers via Maximum Likelihood Estimation (MLE) in an…

Computation and Language · Computer Science 2023-01-20 Shan Wu , Chunlei Xin , Bo Chen , Xianpei Han , Le Sun

Recent studies have demonstrated the overwhelming advantage of cross-lingual pre-trained models (PTMs), such as multilingual BERT and XLM, on cross-lingual NLP tasks. However, existing approaches essentially capture the co-occurrence among…

Computation and Language · Computer Science 2021-03-23 Xiangpeng Wei , Rongxiang Weng , Yue Hu , Luxi Xing , Heng Yu , Weihua Luo

Sentence Representation Learning (SRL) is a fundamental task in Natural Language Processing (NLP), with the Contrastive Learning of Sentence Embeddings (CSE) being the mainstream technique due to its superior performance. An intriguing…

Computation and Language · Computer Science 2023-12-20 Mingxin Li , Richong Zhang , Zhijie Nie , Yongyi Mao

Medical image segmentation is a fundamental yet challenging task due to the arduous process of acquiring large volumes of high-quality labeled data from experts. Contrastive learning offers a promising but still problematic solution to this…

Computer Vision and Pattern Recognition · Computer Science 2025-02-14 Shuang Zeng , Lei Zhu , Xinliang Zhang , Micky C Nnamdi , Wenqi Shi , J Ben Tamo , Qian Chen , Hangzhou He , Lujia Jin , Zifeng Tian , Qiushi Ren , Zhaoheng Xie , Yanye Lu

Contrastive learning has achieved remarkable success on various high-level tasks, but there are fewer contrastive learning-based methods proposed for low-level tasks. It is challenging to adopt vanilla contrastive learning technologies…

Computer Vision and Pattern Recognition · Computer Science 2023-07-18 Gang Wu , Junjun Jiang , Xianming Liu

Contrastive learning has gained significant attention in short text clustering, yet it has an inherent drawback of mistakenly identifying samples from the same category as negatives and then separating them in the feature space (false…

Machine Learning · Computer Science 2026-03-16 Zhihao Yao

Large Language Models (LLMs) have shown strong performance in text-based healthcare tasks. However, their utility in image-based applications remains unexplored. We investigate the effectiveness of LLMs for medical imaging tasks,…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Felicia Liu , Jay J. Yoo , Farzad Khalvati

While Large Language Models (LLMs) demonstrate exceptional performance in surface-level text generation, their nature in handling complex multi-step reasoning tasks often remains one of ``statistical fitting'' rather than systematic logical…

Machine Learning · Computer Science 2026-01-27 Lianlei Shan , Han Chen , Yixuan Wang , Zhenjie Liu , Wei Li

Learning a deep model from small data is yet an opening and challenging problem. We focus on one-shot classification by deep learning approach based on a small quantity of training samples. We proposed a novel deep learning approach named…

Machine Learning · Computer Science 2018-02-13 Chuanyun Xu , Yang Zhang , Xin Feng , YongXing Ge , Yihao Zhang , Jianwu Long

Contrastive learning is a well-established paradigm in representation learning. The standard framework of contrastive learning minimizes the distance between "similar" instances and maximizes the distance between dissimilar ones in the…

Machine Learning · Computer Science 2025-02-06 Naghmeh Ghanooni , Barbod Pajoum , Harshit Rawal , Sophie Fellenz , Vo Nguyen Le Duy , Marius Kloft

The major paradigm of applying a pre-trained language model to downstream tasks is to fine-tune it on labeled task data, which often suffers instability and low performance when the labeled examples are scarce.~One way to alleviate this…

Computation and Language · Computer Science 2021-06-07 Ruikun Luo , Guanhuan Huang , Xiaojun Quan

Single-cell foundation models such as scGPT represent a significant advancement in single-cell omics, with an ability to achieve state-of-the-art performance on various downstream biological tasks. However, these models are inherently…

Machine Learning · Computer Science 2025-07-15 Steven Palayew , Bo Wang , Gary Bader

Although melanoma occurs more rarely than several other skin cancers, patients' long term survival rate is extremely low if the diagnosis is missed. Diagnosis is complicated by a high discordance rate among pathologists when distinguishing…

Computer Vision and Pattern Recognition · Computer Science 2022-10-11 Sean Grullon , Vaughn Spurrier , Jiayi Zhao , Corey Chivers , Yang Jiang , Kiran Motaparthi , Michael Bonham , Julianna Ianni

In modern e-commerce search systems, dense retrieval has become an indispensable component. By computing similarities between query and item (product) embeddings, it efficiently selects candidate products from large-scale repositories. With…

Information Retrieval · Computer Science 2025-10-20 Jianting Tang , Dongshuai Li , Tao Wen , Fuyu Lv , Dan Ou , Linli Xu

Contrastive loss is a powerful approach for representation learning, where larger batch sizes enhance performance by providing more negative samples to better distinguish between similar and dissimilar data. However, scaling batch sizes is…

Computer Vision and Pattern Recognition · Computer Science 2024-10-23 Zesen Cheng , Hang Zhang , Kehan Li , Sicong Leng , Zhiqiang Hu , Fei Wu , Deli Zhao , Xin Li , Lidong Bing

Neural networks exhibit severe brittleness to semantically irrelevant transformations. A mere 75ms electrocardiogram (ECG) phase shift degrades latent cosine similarity from 1.0 to 0.2, while sensor rotations collapse activity recognition…

Machine Learning · Computer Science 2025-11-20 Zhengyang Shen , Hua Tu , Mayue Shi