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Dynamic contrast-enhanced (DCE) MRI is an evolving imaging technique that provides a quantitative measure of pharmacokinetic (PK) parameters in body tissues, in which series of T1-weighted images are collected following the administration…

Computer Vision and Pattern Recognition · Computer Science 2018-06-13 Cagdas Ulas , Giles Tetteh , Michael J. Thrippleton , Paul A. Armitage , Stephen D. Makin , Joanna M. Wardlaw , Mike E. Davies , Bjoern H. Menze

Dynamic Contrast-enhanced Magnetic Resonance Imaging (DCE-MRI) is an important tool for detecting subtle kinetic changes in cancerous tissue. Quantitative analysis of DCE-MRI typically involves the convolution of an arterial input function…

Applications · Statistics 2020-04-22 Volker J. Schmid , Brandon Whitcher , Anwar R. Padhani , Guang-Zhong Yang

Tracer kinetic modeling serves a vital role in diagnosis, treatment planning, tracer development and oncology, but burdens practitioners with complex and invasive arterial input function estimation (AIF). We adopt a physics-informed…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Christian Salomonsen , Samuel Kuttner , Michael Kampffmeyer , Robert Jenssen , Kristoffer Wickstrøm , Jong Chul Ye , Elisabeth Wetzer

Recently, the cycle-consistent generative adversarial networks (CycleGAN) has been widely used for synthesis of multi-domain medical images. The domain-specific nonlinear deformations captured by CycleGAN make the synthesized images…

Computer Vision and Pattern Recognition · Computer Science 2018-08-14 Chengjia Wang , Gillian Macnaught , Giorgos Papanastasiou , Tom MacGillivray , David Newby

Recently, deep learning approaches have been extensively studied for low-dose CT denoising thanks to its superior performance despite the fast computational time. In particular, cycleGAN has been demonstrated as a powerful unsupervised…

Image and Video Processing · Electrical Eng. & Systems 2020-08-14 Jawook Gu , Jong Chul Ye

Recently, deep learning approaches for accelerated MRI have been extensively studied thanks to their high performance reconstruction in spite of significantly reduced runtime complexity. These neural networks are usually trained in a…

Image and Video Processing · Electrical Eng. & Systems 2020-09-01 Gyutaek Oh , Byeongsu Sim , Hyungjin Chung , Leonard Sunwoo , Jong Chul Ye

Lightweight deep learning models offer substantial reductions in computational cost and environmental impact, making them crucial for scientific applications. We present a lightweight CycleGAN for modality transfer in fluorescence…

Computer Vision and Pattern Recognition · Computer Science 2025-10-20 Mohammad Soltaninezhad , Yashar Rouzbahani , Jhonatan Contreras , Rohan Chippalkatti , Daniel Kwaku Abankwa , Christian Eggeling , Thomas Bocklitz

Identifying parameters in partial differential equations (PDEs) represents a very broad class of applied inverse problems. In recent years, several unsupervised learning approaches using (deep) neural networks have been developed to solve…

Numerical Analysis · Mathematics 2025-08-22 Siyu Cen , Bangti Jin , Qimeng Quan , Zhi Zhou

Atrial fibrillation (AF) is a prevalent cardiac arrhythmia associated with elevated health risks, where timely detection is pivotal for mitigating stroke-related morbidity. This study introduces an innovative hybrid methodology integrating…

Machine Learning · Computer Science 2025-10-08 Alireza Jafari , Fereshteh Yousefirizi , Vahid Seydi

Medical imaging plays a vital role in modern diagnostics; however, interpreting high-resolution radiological data remains time-consuming and susceptible to variability among clinicians. Traditional image processing techniques often lack the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Melika Filvantorkaman , Maral Filvan Torkaman

Anomaly detection in images plays a significant role for many applications across all industries, such as disease diagnosis in healthcare or quality assurance in manufacturing. Manual inspection of images, when extended over a monotonously…

Computer Vision and Pattern Recognition · Computer Science 2021-07-21 Vincent Wilmet , Sauraj Verma , Tabea Redl , Håkon Sandaker , Zhenning Li

Learning inter-domain mappings from unpaired data can improve performance in structured prediction tasks, such as image segmentation, by reducing the need for paired data. CycleGAN was recently proposed for this problem, but critically…

Machine Learning · Computer Science 2018-06-20 Amjad Almahairi , Sai Rajeswar , Alessandro Sordoni , Philip Bachman , Aaron Courville

Clinical decision support using deep neural networks has become a topic of steadily growing interest. While recent work has repeatedly demonstrated that deep learning offers major advantages for medical image classification over traditional…

Image and Video Processing · Electrical Eng. & Systems 2022-06-10 Alexander Katzmann , Oliver Taubmann , Stephen Ahmad , Alexander Mühlberg , Michael Sühling , Horst-Michael Groß

Magnetic Resonance Imaging (MRI) scans acquired from different scanners or institutions often suffer from domain shifts owing to variations in hardware, protocols, and acquisition parameters. This discrepancy degrades the performance of…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Mohd Usama , Belal Ahmad , Faleh Menawer R Althiyabi

Artificial intelligence has made great progress in medical data analysis, but the lack of robustness and trustworthiness has kept these methods from being widely deployed. As it is not possible to train networks that are accurate in all…

Machine Learning · Computer Science 2024-02-19 Christopher Wiedeman , Ge Wang

The quantification of myocardial perfusion MRI has the potential to provide a fast, automated and user-independent assessment of myocardial ischaemia. However, due to the relatively high noise level and low temporal resolution of the…

Image and Video Processing · Electrical Eng. & Systems 2019-07-30 Cian M. Scannell , Piet van den Bosch , Amedeo Chiribiri , Jack Lee , Marcel Breeuwer , Mitko Veta

Purpose: The objective of this work is to introduce an advanced framework designed to enhance ultrasound images, especially those captured by portable hand-held devices, which often produce lower quality images due to hardware constraints.…

Image and Video Processing · Electrical Eng. & Systems 2024-12-19 Shreeram Athreya , Ashwath Radhachandran , Vedrana Ivezić , Vivek Sant , Corey W. Arnold , William Speier

Tagged magnetic resonance imaging (MRI) is a widely used imaging technique for measuring tissue deformation in moving organs. Due to tagged MRI's intrinsic low anatomical resolution, another matching set of cine MRI with higher resolution…

Image and Video Processing · Electrical Eng. & Systems 2021-06-08 Xiaofeng Liu , Fangxu Xing , Jerry L. Prince , Aaron Carass , Maureen Stone , Georges El Fakhri , Jonghye Woo

We present a novel method to improve pharmacokinetics modeling, an essential step of drug development. Conventional models frequently fail to fully represent the intricacies of drug absorption and distribution, which limits their predictive…

Quantitative Methods · Quantitative Biology 2024-12-31 Nazanin Ahmadi , Shupeng Wang , George Karniadakis

Understanding how activity in neural circuits reshapes following task learning could reveal fundamental mechanisms of learning. Thanks to the recent advances in neural imaging technologies, high-quality recordings can be obtained from…

Neurons and Cognition · Quantitative Biology 2021-11-29 Bryan M. Li , Theoklitos Amvrosiadis , Nathalie Rochefort , Arno Onken
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