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The cycleGAN is becoming an influential method in medical image synthesis. However, due to a lack of direct constraints between input and synthetic images, the cycleGAN cannot guarantee structural consistency between these two images, and…

While deep learning holds great promise for disease diagnosis and prognosis in cardiac magnetic resonance imaging, its progress is often constrained by highly imbalanced and biased training datasets. To address this issue, we propose a…

Medical image translation is an ill-posed problem. Unlike existing paired unbounded unidirectional translation networks, in this paper, we consider unpaired medical images and provide a strictly bounded network that yields a stable…

The CycleGAN framework allows for unsupervised image-to-image translation of unpaired data. In a scenario of surgical training on a physical surgical simulator, this method can be used to transform endoscopic images of phantoms into images…

Recently, CycleGAN was shown to provide high-performance, ultra-fast denoising for low-dose X-ray computed tomography (CT) without the need for a paired training dataset. Although this was possible thanks to cycle consistency, CycleGAN…

This study investigated the potential of end-to-end deep learning tools as a more effective substitute for FEM in predicting stress-strain fields within 2D cross sections of arterial wall. We first proposed a U-Net based fully convolutional…

The characterization of drug-protein interactions is crucial in the high-throughput screening for drug discovery. The deep learning-based approaches have attracted attention because they can predict drug-protein interactions without…

Cycle reconstruction regularized adversarial training -- e.g., CycleGAN, DiscoGAN, and DualGAN -- has been widely used for image style transfer with unpaired training data. Several recent works, however, have shown that local distortions…

Typically, neural network-based speech dereverberation models are trained on paired data, composed of a dry utterance and its corresponding reverberant utterance. The main limitation of this approach is that such models can only be trained…

In many clinical settings, the use of both Computed Tomography (CT) and Magnetic Resonance (MRI) is necessary to pursue a thorough understanding of the patient's anatomy and to plan a suitable therapeutical strategy; this is often the case…

Inferring adverse events (AEs) of medical products from Spontaneous Reporting Systems (SRS) databases is a core challenge in contemporary pharmacovigilance. Bayesian methods for pharmacovigilance are attractive for their rigorous ability to…

Facial feature tracking is essential in imaging ballistocardiography for accurate heart rate estimation and enables motor degradation quantification in Parkinson's disease through skin feature tracking. While deep convolutional neural…

CycleGAN has been proven to be an advanced approach for unsupervised image restoration. This framework consists of two generators: a denoising one for inference and an auxiliary one for modeling noise to fulfill cycle-consistency…

Synthesizing MR imaging sequences is highly relevant in clinical practice, as single sequences are often missing or are of poor quality (e.g. due to motion). Naturally, the idea arises that a target modality would benefit from multi-modal…

Time-resolved MR angiography (tMRA) has been widely used for dynamic contrast enhanced MRI (DCE-MRI) due to its highly accelerated acquisition. In tMRA, the periphery of the k-space data are sparsely sampled so that neighbouring frames can…

In MRI studies, the aggregation of imaging data from multiple acquisition sites enhances sample size but may introduce site-related variabilities that hinder consistency in subsequent analyses. Deep learning methods for image translation…

Automatic segmentation of white matter hyperintensities in magnetic resonance images is of paramount clinical and research importance. Quantification of these lesions serve as a predictor for risk of stroke, dementia and mortality. During…

Non-parallel training is a difficult but essential task for DNN-based speech enhancement methods, for the lack of adequate noisy and paired clean speech corpus in many real scenarios. In this paper, we propose a novel adaptive…

Magnetic Resonance Imaging (MRI) of the brain can come in the form of different modalities such as T1-weighted and Fluid Attenuated Inversion Recovery (FLAIR) which has been used to investigate a wide range of neurological disorders.…

Conventional and deep learning-based methods have shown great potential in the medical imaging domain, as means for deriving diagnostic, prognostic, and predictive biomarkers, and by contributing to precision medicine. However, these…