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Purpose: Microscopic fractional anisotropy ({\mu}FA) can disentangle microstructural information from orientation dispersion. While double diffusion encoding (DDE) MRI methods are widely used to extract accurate {\mu}FA, it has only…

Medical Physics · Physics 2019-03-21 Rafael Neto Henriques , Sune N Jespersen , Noam Shemesh

Diffusion-weighted magnetic resonance imaging (DW-MRI) is a non-invasive way of imaging white matter tracts in the human brain. DW-MRIs are usually acquired using echo-planar imaging (EPI) with high gradient fields, which could introduce…

Image and Video Processing · Electrical Eng. & Systems 2023-04-04 Zhangxing Bian , Muhan Shao , Aaron Carass , Jerry L. Prince

Diffusion magnetic resonance imaging (dMRI) is a relatively modern technique used to study tissue microstructure in a non-invasive way. Non-Gaussian diffusion representation is related to the restricted diffusion and can provide information…

Signal Processing · Electrical Eng. & Systems 2020-09-17 Tomasz Pieciak , Maryam Afzali , Fabian Bogusz , Aja-Fernández , Derek K. Jones

Diffusion magnetic resonance imaging is a noninvasive imaging technique that can indirectly infer the microstructure of tissues and provide metrics which are subject to normal variability across subjects. Potentially abnormal values or…

Image and Video Processing · Electrical Eng. & Systems 2020-08-28 Samuel St-Jean , Max A. Viergever , Alexander Leemans

Exchange between tissue compartments is crucial for interpretation of diffusion MRI measurements in brain gray matter. However, reported values of exchange time are broadly dispersed, about two orders of magnitude. We analyze the…

Biological Physics · Physics 2026-03-24 Valerij G. Kiselev , Jing-Rebecca Li

The integrity of articular cartilage is a crucial aspect in the early diagnosis of osteoarthritis (OA). Many novel MRI techniques have the potential to assess compositional changes of the cartilage extracellular matrix. Among these…

Computer Vision and Pattern Recognition · Computer Science 2019-12-05 Alejandra Duarte , Chaitra V. Hegde , Aakash Kaku , Sreyas Mohan , José G. Raya

Modelling the diffusion-relaxation magnetic resonance (MR) signal obtained from multi-parametric sequences has recently gained immense interest in the community due to new techniques significantly reducing data acquisition time. A preferred…

Medical Physics · Physics 2025-01-28 Fabian Bogusz , Tomasz Pieciak

Diffusion MRI measures of the human brain provide key insight into microstructural variations across individuals and into the impact of central nervous system diseases and disorders. One approach to extract information from diffusion…

Medical Physics · Physics 2022-01-19 Qianqian Yang , David C. Reutens , Viktor Vegh

Diffusion tensor imaging (DTI) is a prevalent neuroimaging tool in analyzing the anatomical structure. The distinguishing feature of DTI is that the voxel-wise variable is a 3x3 positive definite matrix other than a scalar, describing the…

Methodology · Statistics 2021-03-30 Zhou Lan

Multi-echo Gradient Echo (mGRE) sequences provide valuable quantitative parametric maps, such as Quantitative Susceptibility Mapping (QSM) and transverse relaxation rate (R2*), sensitive to tissue iron and myelin. However, structural…

Image and Video Processing · Electrical Eng. & Systems 2025-12-02 Sizhe Fang , Deqiang Qiu

Diffusion MRI (dMRI) provides the ability to reconstruct neuronal fibers in the brain, $\textit{in vivo}$, by measuring water diffusion along angular gradient directions in q-space. High angular resolution diffusion imaging (HARDI) can…

Machine Learning · Statistics 2018-05-30 Evan Schwab , René Vidal , Nicolas Charon

Diffusion MRI is a modern neuroimaging modality with a unique ability to acquire microstructural information by measuring water self-diffusion at the voxel level. However, it generates huge amounts of data, resulting from a large number of…

Image and Video Processing · Electrical Eng. & Systems 2023-04-06 Ikram Jumakulyyev , Thomas Schultz

Accurate segmentation of ischemic stroke lesions from diffusion magnetic resonance imaging (MRI) is essential for clinical decision-making and outcome assessment. Diffusion-Weighted Imaging (DWI) and Apparent Diffusion Coefficient (ADC)…

Image and Video Processing · Electrical Eng. & Systems 2025-12-24 Muhammad Usman , Azka Rehman , Muhammad Mutti Ur Rehman , Abd Ur Rehman , Muhammad Umar Farooq

Mapping white matter tracts is an essential step towards understanding brain function. Diffusion Magnetic Resonance Imaging (dMRI) is the only noninvasive technique which can detect in vivo anisotropies in the 3-dimensional diffusion of…

Computation · Statistics 2014-03-21 Dario Gasbarra , Jia Liu , Juha Railavo

Magnetic Resonance Imaging (MRI), including diffusion MRI (dMRI), serves as a ``microscope'' for anatomical structures and routinely mitigates the influence of low signal-to-noise ratio scans by compromising temporal or spatial resolution.…

Image and Video Processing · Electrical Eng. & Systems 2025-03-11 Chenxu Wu , Qingpeng Kong , Zihang Jiang , S. Kevin Zhou

We introduce a new framework called DiffGEPCI for cross-modality generation in magnetic resonance imaging (MRI) using a 2.5D conditional diffusion model. DiffGEPCI can synthesize high-quality Fluid Attenuated Inversion Recovery (FLAIR) and…

Image and Video Processing · Electrical Eng. & Systems 2024-04-22 Yuyang Hu , Satya V. V. N. Kothapalli , Weijie Gan , Alexander L. Sukstanskii , Gregory F. Wu , Manu Goyal , Dmitriy A. Yablonskiy , Ulugbek S. Kamilov

Diffusion MRI (dMRI) is a valuable tool to map brain microstructure and connectivity by analyzing water molecule diffusion in tissue. However, acquiring dMRI data requires to capture multiple 3D brain volumes in a short time, often leading…

Image and Video Processing · Electrical Eng. & Systems 2025-08-29 Sedigheh Dargahi , Sylvain Bouix , Christian Desrosiers

Multi-contrast MRI methods acquire multiple images with different contrast weightings, which are used for the differentiation of the tissue types or quantitative mapping. However, the scan time needed to acquire multiple contrasts is…

Image and Video Processing · Electrical Eng. & Systems 2025-02-18 Yan Chen , Jyothi Rikhab Chand , Steven R. Kecskemeti , James H. Holmes , Mathews Jacob

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is essential for breast cancer diagnosis due to its ability to characterize tissue through contrast agent kinetics. However, traditional DCE-MRI protocols require multiple…

Computer Vision and Pattern Recognition · Computer Science 2025-01-28 Ruben D. Fonnegra , Maria Liliana Hernández , Juan C. Caicedo , Gloria M. Díaz

Robust diffusion adaptive estimation algorithms based on the maximum correntropy criterion (MCC), including adaptation to combination MCC and combination to adaptation MCC, are developed to deal with the distributed estimation over network…

Machine Learning · Statistics 2016-02-04 Wentao Ma , Badong Chen , Jiandong Duan , Haiquan Zhao