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Downsampling or under-sampling is a technique that is utilized in the context of large and highly imbalanced classification models. We study optimal downsampling for imbalanced classification using generalized linear models (GLMs). We…

Machine Learning · Statistics 2025-05-20 Yan Chen , Jose Blanchet , Krzysztof Dembczynski , Laura Fee Nern , Aaron Flores

The rapid emergence of single-cell data has facilitated the study of many different biological conditions at the cellular level. Cluster analysis has been widely applied to identify cell types, capturing the essential patterns of the…

Genomics · Quantitative Biology 2025-02-03 Sebastian Pena , Lin Lin , Jia Li

In this work, we propose a novel approach for subgraph matching, the problem of finding a given query graph in a large source graph, based on the fused Gromov-Wasserstein distance. We formulate the subgraph matching problem as a partial…

Information Theory · Computer Science 2024-07-01 Wen-Xin Pan , Isabel Haasler , Pascal Frossard

In the relentless efforts in enhancing medical diagnostics, the integration of state-of-the-art machine learning methodologies has emerged as a promising research area. In molecular biology, there has been an explosion of data generated…

Machine Learning · Computer Science 2024-05-17 Ibrahim Al-Hurani , Abedalrhman Alkhateeb , Salama Ikki

Despite the unprecedented performance of deep neural networks (DNNs) in computer vision, their practical application in the diagnosis and prognosis of cancer using medical imaging has been limited. One of the critical challenges for…

Machine Learning · Computer Science 2023-04-27 Lennart Brocki , Neo Christopher Chung

Millimeter-wave (mmWave) communication is a promising technology to cope with the exponential increase in 5G data traffic. Such networks typically require a very dense deployment of base stations. A subset of those, so-called macro base…

Networking and Internet Architecture · Computer Science 2020-07-07 Dingwen Yuan , Hsuan-Yin Lin , Jörg Widmer , Matthias Hollick

Identifying a small molecule from its mass spectrum is the primary open problem in computational metabolomics. This is typically cast as information retrieval: an unknown spectrum is matched against spectra predicted computationally from a…

Machine Learning · Computer Science 2023-01-30 Michael Murphy , Stefanie Jegelka , Ernest Fraenkel , Tobias Kind , David Healey , Thomas Butler

Many diseases cause significant changes to the concentrations of small molecules (aka metabolites) that appear in a person's biofluids, which means such diseases can often be readily detected from a person's "metabolic profile". This…

Unsupervised integrative analysis of multiple data sources has become common place and scalable algorithms are necessary to accommodate ever increasing availability of data. Only few currently methods have estimation speed as their focus,…

Methodology · Statistics 2024-05-17 Felix Held

Data-driven automatic approaches have demonstrated their great potential in resolving various clinical diagnostic dilemmas in neuro-oncology, especially with the help of standard anatomic and advanced molecular MR images. However, data…

Image and Video Processing · Electrical Eng. & Systems 2020-08-10 Pengfei Guo , Puyang Wang , Rajeev Yasarla , Jinyuan Zhou , Vishal M. Patel , Shanshan Jiang

Semi-supervised learning has made remarkable strides by effectively utilizing a limited amount of labeled data while capitalizing on the abundant information present in unlabeled data. However, current algorithms often prioritize aligning…

Computer Vision and Pattern Recognition · Computer Science 2024-05-31 Zhiquan Tan , Kaipeng Zheng , Weiran Huang

Systems Biology is a fundamental field and paradigm that introduces a new era in Biology. The crux of its functionality and usefulness relies on metabolic networks that model the reactions occurring inside an organism and provide the means…

Quantitative Methods · Quantitative Biology 2022-06-03 Apostolos Chalkis , Vissarion Fisikopoulos , Elias Tsigaridas , Haris Zafeiropoulos

Enrichment of predictive models with new biomolecular markers is an important task in high-dimensional omic applications. Increasingly, clinical studies include several sets of such omics markers available for each patient, measuring…

Accurate mobile device localization is critical for emerging 5G/6G applications such as autonomous vehicles and augmented reality. In this paper, we propose a unified localization method that integrates model-based and machine learning…

Signal Processing · Electrical Eng. & Systems 2025-09-09 Yuhao Zhang , Guangjin Pan , Musa Furkan Keskin , Ossi Kaltiokallio , Mikko Valkama , Henk Wymeersch

By building upon the recent theory that established the connection between implicit generative modeling (IGM) and optimal transport, in this study, we propose a novel parameter-free algorithm for learning the underlying distributions of…

Machine Learning · Statistics 2019-06-12 Antoine Liutkus , Umut Şimşekli , Szymon Majewski , Alain Durmus , Fabian-Robert Stöter

Untargeted metabolomic studies are revealing large numbers of naturally occurring metabolites that cannot be characterized because their chemical structures and MS/MS spectra are not available in databases. Here we present iMet, a…

Quantitative Methods · Quantitative Biology 2017-03-17 Antoni Aguilar-Mogas , Marta Sales-Pardo , Miriam Navarro , Ralf Tautenhahn , Roger Guimerà , Oscar Yanes

Integrating large language model (LLM) representations into multimodal recommendation has shown promise, yet a fundamental challenge remains largely overlooked: the semantic heterogeneity between generative LM representations and the…

Information Retrieval · Computer Science 2026-05-26 Yuecheng Li , Hengwei Ju , Zeyu Song , Wei Yang , Chi Lu , Peng Jiang , Kun Gai

Selecting the best data mixture is critical for successful Supervised Fine-Tuning (SFT) of Multimodal Large Language Models. However, determining the optimal mixture weights across multiple domain-specific datasets remains a significant…

Machine Learning · Computer Science 2026-02-06 Davide Berasi , Matteo Farina , Massimiliano Mancini , Elisa Ricci

In this paper, we focus on a new method of data augmentation to solve the data imbalance problem within imbalanced ECG datasets to improve the robustness and accuracy of heart disease detection. By using Optimal Transport, we augment the…

Signal Processing · Electrical Eng. & Systems 2023-02-20 Jielin Qiu , Jiacheng Zhu , Mengdi Xu , Peide Huang , Michael Rosenberg , Douglas Weber , Emerson Liu , Ding Zhao

Recent years have seen a focus on research into distributed optimization algorithms for multi-robot Collaborative Simultaneous Localization and Mapping (C-SLAM). Research in this domain, however, is made difficult by a lack of standard…

Robotics · Computer Science 2025-09-16 Daniel McGann , Easton R. Potokar , Michael Kaess
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