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We introduce a novel training strategy for stereo matching and optical flow estimation that utilizes image-to-image translation between synthetic and real image domains. Our approach enables the training of models that excel in real image…

Computer Vision and Pattern Recognition · Computer Science 2023-09-06 Zhexiao Xiong , Feng Qiao , Yu Zhang , Nathan Jacobs

Coarse-grained (CG) molecular simulations have become a standard tool to study molecular processes on time- and length-scales inaccessible to all-atom simulations. Parameterizing CG force fields to match all-atom simulations has mainly…

Computational Physics · Physics 2023-02-07 Jonas Köhler , Yaoyi Chen , Andreas Krämer , Cecilia Clementi , Frank Noé

Zero-shot object counting aims to count instances of arbitrary object categories specified by text descriptions. Existing methods typically rely on vision-language models like CLIP, but often exhibit limited sensitivity to text prompts. We…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Yifei Qian , Zhongliang Guo , Bowen Deng , Chun Tong Lei , Shuai Zhao , Chun Pong Lau , Xiaopeng Hong , Michael P. Pound

Using techniques borrowed from statistical physics and neural networks, we determine the parameters, associated with a scoring function, that are chosen optimally to ensure complete success in threading tests in a training set of proteins.…

Soft Condensed Matter · Physics 2009-11-07 Iksoo Chang , Marek Cieplak , Ruxandra I. Dima , Amos Maritan , Jayanth R. Banavar

Simulating atomic-scale processes, such as protein dynamics and catalytic reactions, is crucial for advancements in biology, chemistry, and materials science. Machine learning force fields (MLFFs) have emerged as powerful tools that achieve…

Chemical Physics · Physics 2024-12-30 Lars L. Schaaf , Ilyes Batatia , Christoph Brunken , Thomas D. Barrett , Jules Tilly

The recent Segment Anything Model (SAM) 2 has demonstrated remarkable foundational competence in semantic segmentation, with its memory mechanism and mask decoder further addressing challenges in video tracking and object occlusion, thereby…

Computer Vision and Pattern Recognition · Computer Science 2024-08-09 Jieming Yu , An Wang , Wenzhen Dong , Mengya Xu , Mobarakol Islam , Jie Wang , Long Bai , Hongliang Ren

Visual localization is considered to be one of the crucial parts in many robotic and vision systems. While state-of-the art methods that relies on feature matching have proven to be accurate for visual localization, its requirements for…

Computer Vision and Pattern Recognition · Computer Science 2025-03-19 Huy-Hoang Bui , Bach-Thuan Bui , Quang-Vinh Tran , Yasuyuki Fujii , Joo-Ho Lee

Conformational ensembles of protein structures are immensely important both for understanding protein function and drug discovery in novel modalities such as cryptic pockets. Current techniques for sampling ensembles such as molecular…

Biological Physics · Physics 2025-10-24 Ameya Daigavane , Bodhi P. Vani , Darcy Davidson , Saeed Saremi , Joshua Rackers , Joseph Kleinhenz

Stochastic gradient Markov chain Monte Carlo (SG-MCMC) methods are Bayesian analogs to popular stochastic optimization methods; however, this connection is not well studied. We explore this relationship by applying simulated annealing to an…

Machine Learning · Statistics 2016-08-08 Changyou Chen , David Carlson , Zhe Gan , Chunyuan Li , Lawrence Carin

The field of machine learning for drug discovery is witnessing an explosion of novel methods. These methods are often benchmarked on simple physicochemical properties such as solubility or general druglikeness, which can be readily…

Understanding the geometry of learned distributions is fundamental to improving and interpreting diffusion models, yet systematic tools for exploring their landscape remain limited. Standard latent-space interpolations fail to respect the…

Machine Learning · Statistics 2026-02-26 Elio Moreau , Florentin Coeurdoux , Grégoire Ferre , Eric Vanden-Eijnden

Designing functional protein sequences that satisfy multiple desired properties is a core research focus of protein engineering. Prior methods struggle with inability or inefficiency when dealing with numerous, often conflicting,…

Biomolecules · Quantitative Biology 2026-05-08 Zitai Kong , Yifan Dong , Yixuan Wu , Zhaokang Liang , Jian Wu , Hongxia Xu

Recent research has shown that non-additive image steganographic frameworks effectively improve security performance through adjusting distortion distribution. However, as far as we know, all of the existing non-additive proposals are based…

Multimedia · Computer Science 2021-08-11 Xianbo Mo , Shunquan Tan , Bin Li , Jiwu Huang

The choice of structural resolution is a fundamental aspect of protein modelling, determining the balance between descriptive power and interpretability. Although atomistic simulations provide maximal detail, much of this information is…

Biomolecules · Quantitative Biology 2025-10-23 Margherita Mele , Raffaele Fiorentini , Thomas Tarenzi , Giovanni Mattiotti , Raffaello Potestio

Molecular dynamics simulations have emerged as a fundamental instrument for studying biomolecules. At the same time, it is desirable to perform simulations of a collection of particles under various conditions in which the molecules can…

Machine Learning · Computer Science 2023-10-11 Jingbang Chen , Yian Wang , Xingwei Qu , Shuangjia Zheng , Yaodong Yang , Hao Dong , Jie Fu

Speech Translation (ST) is the task of translating speech in one language into text in another language. Traditional cascaded approaches for ST, using Automatic Speech Recognition (ASR) and Machine Translation (MT) systems, are prone to…

Computation and Language · Computer Science 2021-07-14 Tu Anh Dinh

Structural equation models are commonly used to capture the relationship between sets of observed and unobservable variables. Traditionally these models are fitted using frequentist approaches but recently researchers and practitioners have…

Methodology · Statistics 2023-02-22 Khue-Dung Dang , Luca Maestrini

Zero-shot learning (ZSL) endows the computer vision system with the inferential capability to recognize instances of a new category that has never seen before. Two fundamental challenges in it are visual-semantic embedding and domain…

Computer Vision and Pattern Recognition · Computer Science 2017-03-28 Yunlong Yu , Zhong Ji , Jichang Guo , Yanwei Pang

End-to-end Speech Translation (ST) aims at translating the source language speech into target language text without generating the intermediate transcriptions. However, the training of end-to-end methods relies on parallel ST data, which…

Computation and Language · Computer Science 2022-10-19 Chen Wang , Yuchen Liu , Boxing Chen , Jiajun Zhang , Wei Luo , Zhongqiang Huang , Chengqing Zong

This paper introduces a novel model-free approach to synthesize virtual sensors for the estimation of dynamical quantities that are unmeasurable at runtime but are available for design purposes on test benches. After collecting a dataset of…

Optimization and Control · Mathematics 2021-03-24 Daniele Masti , Daniele Bernardini , Alberto Bemporad