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Deep neural networks with discrete latent variables offer the promise of better symbolic reasoning, and learning abstractions that are more useful to new tasks. There has been a surge in interest in discrete latent variable models, however,…

Machine Learning · Computer Science 2018-07-23 Aurko Roy , Ashish Vaswani , Arvind Neelakantan , Niki Parmar

We present a systematic investigation of convolutional autoencoders for the reduced-order representation of three-dimensional interfacial multiphase flows. Focusing on the reconstruction of phase indicators, we examine how the choice of…

Computational Engineering, Finance, and Science · Computer Science 2025-12-29 Murray Cutforth , Shahab Mirjalili

Thermally Activated Delayed Fluorescence (TADF) emitters must satisfy two competing requirements: small singlet-triplet energy gaps for thermal upconversion and sufficient spin-orbit coupling for fast reverse intersystem crossing.…

Machine learning (ML) models trained to detect physical-layer threats on one optical fiber system often fail catastrophically when applied to a different system, due to variations in operating wavelength, fiber properties, and network…

Understanding kinetics and thermodynamics profile of biomolecules is necessary to understand their functional roles which has a major impact in mechanism driven drug discovery. Molecular dynamics simulation has been routinely used to…

Biomolecules · Quantitative Biology 2021-12-07 Soumendranath Bhakat

Hyperdimensional computing (HDC) offers lightweight learning for energy-constrained devices by encoding data into high-dimensional vectors. However, its reliance on ultra-high dimensionality and static, randomly initialized hypervectors…

Machine Learning · Computer Science 2026-02-03 Hanne Dejonghe , Sam Leroux

Neural network methods are increasingly applied to solve phase transition problems, particularly in identifying critical points in non-equilibrium phase transitions, offering more convenience compared to traditional methods. In this paper,…

Statistical Mechanics · Physics 2025-03-12 Feng Gao , Jianmin Shen , Shanshan Wang , Wei Li , Dian Xu

We review recent results of molecular dynamics simulations of two models of liquid water, the extended simple point charge (SPC/E) and the Mahoney-Jorgensen transferable intermolecular potential with five points (TIP5P), which is closer to…

Soft Condensed Matter · Physics 2007-05-23 H. E. Stanley , M. C. Barbosa , S. Mossa , P. A. Netz , F. Sciortino , F. W. Starr , M. Yamada

We propose a latent space dynamics identification method, namely tLaSDI, that embeds the first and second principles of thermodynamics. The latent variables are learned through an autoencoder as a nonlinear dimension reduction model. The…

Machine Learning · Computer Science 2024-03-25 Jun Sur Richard Park , Siu Wun Cheung , Youngsoo Choi , Yeonjong Shin

Metadynamics, a member of the `flat histogram' class of advanced sampling algorithms, has been widely used in molecular simulations to drive the exploration of states separated by high free energy barriers and promote comprehensive sampling…

Computational Physics · Physics 2021-09-13 Shanghui Huang , Michael J. Quevillon , Ernesto C. Cortés-Morales , Jonathan K. Whitmer

Machine learning (ML) techniques have been demonstrated to improve the accuracy and efficiency of anomaly detection (AD) when compared to conventional methods. This has led to the adoption of ML for data quality monitoring (DQM) use cases…

Two-dimensional materials are expected to play an important role in next-generation electronics and optoelectronic devices. Recently, twisted bilayer graphene and transition metal dichalcogenides have attracted significant attention due to…

Two-dimensional transition metal dichalcogenides (TMDs) represent an ideal testbench for the search of materials by design, because their optoelectronic properties can be manipulated through surface engineering and molecular…

Recent advances in deep generative modeling have enabled efficient modeling of high dimensional data distributions and opened up a new horizon for solving data compression problems. Specifically, autoencoder based learned image or video…

Machine Learning · Computer Science 2020-04-10 Adam Golinski , Reza Pourreza , Yang Yang , Guillaume Sautiere , Taco S Cohen

This paper introduces Associative Compression Networks (ACNs), a new framework for variational autoencoding with neural networks. The system differs from existing variational autoencoders (VAEs) in that the prior distribution used to model…

Neural and Evolutionary Computing · Computer Science 2018-04-27 Alex Graves , Jacob Menick , Aaron van den Oord

This study explores the development of a hybrid deep convolutional neural network (DCNN) model enhanced by autoencoders and data augmentation techniques to predict critical heat flux (CHF) with high accuracy. By augmenting the original…

Machine Learning · Computer Science 2024-08-28 Messaoud Djeddou , Aouatef Hellal , Ibrahim A. Hameed , Xingang Zhao , Djehad Al Dallal

The use of accelerated sampling methods such as metadynamics has shown significant advantage in calculations that involve infrequent events, which would otherwise require sampling a prohibitive number of configurations to determine, e.g.,…

Chemical Physics · Physics 2023-09-28 Jiasen Guo , Alberto Albesa , Carlos Wexler

Variational Autoencoders (VAEs), as a form of deep generative model, have been widely used in recent years, and shown great great peformance in a number of different domains, including image generation and anomaly detection, etc.. This…

Machine Learning · Computer Science 2024-08-28 Liang Cheng , Peiyuan Guan , Amir Taherkordi , Lei Liu , Dapeng Lan

Without knowledge of specific pockets, generating ligands based on the global structure of a protein target plays a crucial role in drug discovery as it helps reduce the search space for potential drug-like candidates in the pipeline.…

Biomolecules · Quantitative Biology 2023-10-02 Nhat Khang Ngo , Truong Son Hy

For nearly the past 30 years, Centroid Molecular Dynamics (CMD) has proven to be a viable classical-like phase space formulation for the calculation of quantum dynamical properties. However, calculation of the centroid effective force…

Chemical Physics · Physics 2022-09-15 Timothy D. Loose , Patrick G. Sahrmann , Gregory A. Voth