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Conditional neural processes (CNPs) are a flexible and efficient family of models that learn to learn a stochastic process from data. They have seen particular application in contextual image completion - observing pixel values at some…

Machine Learning · Computer Science 2024-02-20 Victor Prokhorov , Ivan Titov , N. Siddharth

Conformational sampling of biomolecules using molecular dynamics simulations often produces large amount of high dimensional data that makes it difficult to interpret using conventional analysis techniques. Dimensionality reduction methods…

Biomolecules · Quantitative Biology 2021-12-08 Mahdi Ghorbani , Samarjeet Prasad , Jeffery B. Klauda , Bernard R. Brooks

Understanding the behavior of complex molecular systems is a fundamental problem in physical chemistry. To describe the long-time dynamics of such systems, which is responsible for their most informative characteristics, we can identify a…

Chemical Physics · Physics 2024-09-11 Jakub Rydzewski

The increasing number of protein-based metamaterials demands reliable and efficient theoretical and computational methods to study the physicochemical properties they may display. In this regard, we develop a simulation strategy based on…

Soft Condensed Matter · Physics 2020-06-23 J. A. Campos Gonzalez Angulo , G. Wiesehan , R. F. Ribeiro , J. Yuen-Zhou

A reliable prediction of 3D protein structures from sequence data remains a big challenge due to both theoretical and computational difficulties. We have previously shown that our kinetostatic compliance method (KCM) implemented into the…

Computational Engineering, Finance, and Science · Computer Science 2017-12-27 Pouya Tavousi , Morad Behandish , Horea T. Ilies , Kazem Kazerounian

Learning latent representations of registered meshes is useful for many 3D tasks. Techniques have recently shifted to neural mesh autoencoders. Although they demonstrate higher precision than traditional methods, they remain unable to…

Computer Vision and Pattern Recognition · Computer Science 2020-10-22 Yi Zhou , Chenglei Wu , Zimo Li , Chen Cao , Yuting Ye , Jason Saragih , Hao Li , Yaser Sheikh

We train active neural-network flow controllers using a deep learning PDE augmentation method to optimize lift-to-drag ratios in turbulent airfoil flows at Reynolds number $5\times10^4$ and Mach number 0.4. Direct numerical simulation and…

Fluid Dynamics · Physics 2025-10-09 Xuemin Liu , Tom Hickling , Jonathan F. MacArt

A combined convolutional autoencoder-recurrent neural network machine learning model is presented to analyse and forecast the dynamics and low-order statistics of the local convective heat flux field in a two-dimensional turbulent…

Fluid Dynamics · Physics 2022-04-13 Sandeep Pandey , Philipp Teutsch , Patrick Mäder , Jörg Schumacher

While many phenomena in physics and engineering are formally high-dimensional, their long-time dynamics often live on a lower-dimensional manifold. The present work introduces an autoencoder framework that combines implicit regularization…

Machine Learning · Computer Science 2023-12-07 Kevin Zeng , Carlos E. Pérez De Jesús , Andrew J. Fox , Michael D. Graham

Autoencoders are the simplest neural network for unsupervised learning, and thus an ideal framework for studying feature learning. While a detailed understanding of the dynamics of linear autoencoders has recently been obtained, the study…

Machine Learning · Statistics 2022-08-01 Maria Refinetti , Sebastian Goldt

The interaction of condensed phase systems with external electric fields is crucial in myriad processes in nature and technology ranging from the field-directed motion of cells (galvanotaxis), to energy storage and conversion systems…

Chemical Physics · Physics 2024-09-25 Kit Joll , Philipp Schienbein , Kevin M. Rosso , Jochen Blumberger

A central challenge in high-energy nuclear physics is to extract informative features from the high-dimensional final-state data of heavy-ion collisions (HIC) in order to enable reliable downstream analyses. Traditional approaches often…

High Energy Physics - Phenomenology · Physics 2025-10-09 Jing-Zong Zhang , Shuang Guo , Li-Lin Zhu , Lingxiao Wang , Guo-Liang Ma

Phase-separated biomolecular condensates exhibit a wide range of dynamical properties, which depend on the sequences of the constituent proteins and RNAs. However, it is unclear to what extent condensate dynamics can be tuned without also…

Biomolecules · Quantitative Biology 2024-07-31 Yaxin An , Michael A. Webb , William M. Jacobs

A common technique in high energy physics is to characterize the response of a detector by means of models tunned to data which build parametric maps from the physical parameters of the system to the expected signal of the detector. When…

Instrumentation and Detectors · Physics 2022-06-29 César Jesús-Valls , Thorsten Lux , Federico Sánchez

Well-Tempered Metadynamics (WTmetaD) is an efficient method to enhance the reconstruction of the free-energy surface of proteins. WTmetaD guarantees a faster convergence in the long time limit in comparison with the standard metadynamics.…

Biological Physics · Physics 2015-06-12 Francois Sicard , Patrick Senet

Weaving ramps are critical bottlenecks in highway networks due to conflicting traffic flows and complex interactions among heterogeneous vehicle types. In mixed-autonomy settings, the presence of controllable autonomous vehicles (AVs)…

Systems and Control · Electrical Eng. & Systems 2026-04-27 Kexin Wang , Haohui He , Ruolin Li

We introduce a new framework for training deep generative models for high-dimensional conditional density estimation. The Bottleneck Conditional Density Estimator (BCDE) is a variant of the conditional variational autoencoder (CVAE) that…

Machine Learning · Statistics 2017-07-03 Rui Shu , Hung H. Bui , Mohammad Ghavamzadeh

We propose a new structure for the complex-valued autoencoder by introducing additional degrees of freedom into its design through a widely linear (WL) transform. The corresponding widely linear backpropagation algorithm is also developed…

Neural and Evolutionary Computing · Computer Science 2019-03-07 Zeyang Yu , Shengxi Li , Danilo Mandic

Conventionally, autoencoders are unsupervised representation learning tools. In this work, we propose a novel discriminative autoencoder. Use of supervised discriminative learning ensures that the learned representation is robust to…

Computer Vision and Pattern Recognition · Computer Science 2019-12-30 Anupriya Gogna , Angshul Majumdar

Many problems in science and engineering involve time-dependent, high dimensional datasets arising from complex physical processes, which are costly to simulate. In this work, we propose WeldNet: Windowed Encoders for Learning Dynamics, a…

Machine Learning · Statistics 2025-12-15 Biraj Dahal , Jiahui Cheng , Hao Liu , Rongjie Lai , Wenjing Liao