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Neurons perform computations, and convey the results of those computations through the statistical structure of their output spike trains. Here we present a practical method, grounded in the information-theoretic analysis of prediction, for…

Neurons and Cognition · Quantitative Biology 2022-03-18 Robert Haslinger , Kristina Lisa Klinkner , Cosma Rohilla Shalizi

There is a need for fast adaptation in spike sorting algorithms to implement brain-machine interface (BMIs) in different applications. Learning and adapting the functionality of the sorting process in real-time can significantly improve the…

Signal Processing · Electrical Eng. & Systems 2025-09-08 Tao Fang , Majid Zamani

Efficient pattern separation in dentate gyrus plays an important role in storing information in the hippocampus. Current knowledge of the structure and function of the hippocampus, entorhinal cortex and dentate gyrus, in pattern separation…

Neurons and Cognition · Quantitative Biology 2018-08-02 Faramarz Faghihi , Homa Samani , Ahmed A. Moustafa

The mutual information between stimulus and spike-train response is commonly used to monitor neural coding efficiency, but neuronal computation broadly conceived requires more refined and targeted information measures of input-output joint…

Neurons and Cognition · Quantitative Biology 2015-04-21 Sarah E. Marzen , Michael R. DeWeese , James P. Crutchfield

A main concern in cognitive neuroscience is to decode the overt neural spike train observations and infer latent representations under neural circuits. However, traditional methods entail strong prior on network structure and hardly meet…

Neurons and Cognition · Quantitative Biology 2019-11-22 Zhijie Chen , Junchi Yan , Longyuan Li , Xiaokang Yang

In artificial neural networks trained with gradient descent, the weights used for processing stimuli are also used during backward passes to calculate gradients. For the real brain to approximate gradients, gradient information would have…

Neurons and Cognition · Quantitative Biology 2020-02-04 Jordan Guerguiev , Konrad P. Kording , Blake A. Richards

Spike-based encoders represent information as sequences of spikes or pulses, which are transmitted between neurons. A prevailing consensus suggests that spike-based approaches demonstrate exceptional capabilities in capturing the temporal…

Signal Processing · Electrical Eng. & Systems 2025-06-03 MHD Anas Alsakkal , Runze Wang , Jayawan Wijekoon , Huajin Tang

The apparent stochasticity of in-vivo neural circuits has long been hypothesized to represent a signature of ongoing stochastic inference in the brain. More recently, a theoretical framework for neural sampling has been proposed, which…

Neurons and Cognition · Quantitative Biology 2017-03-14 Mihai A. Petrovici , Ilja Bytschok , Johannes Bill , Johannes Schemmel , Karlheinz Meier

The brain has computational capabilities that surpass those of modern systems, being able to solve complex problems efficiently in a simple way. Neuromorphic engineering aims to mimic biology in order to develop new systems capable of…

Neural and Evolutionary Computing · Computer Science 2023-10-10 Daniel Casanueva-Morato , Alvaro Ayuso-Martinez , Juan P. Dominguez-Morales , Angel Jimenez-Fernandez , Gabriel Jimenez-Moreno

To compensate for sensory processing delays, the visual system must make predictions to ensure timely and appropriate behaviors. Recent work has found predictive information about the stimulus in neural populations early in vision…

Neurons and Cognition · Quantitative Biology 2018-10-05 Audrey J. Sederberg , Jason N. MacLean , Stephanie E. Palmer

Noise in spiking neurons is commonly modeled by a noisy input current or by generating output spikes stochastically with a voltage-dependent hazard rate ("escape noise"). While input noise lends itself to modeling biophysical noise…

Neurons and Cognition · Quantitative Biology 2021-09-16 Tilo Schwalger

Spikes are the currency in central nervous systems for information transmission and processing. They are also believed to play an essential role in low-power consumption of the biological systems, whose efficiency attracts increasing…

Neural and Evolutionary Computing · Computer Science 2020-05-05 Qiang Yu , Shenglan Li , Huajin Tang , Longbiao Wang , Jianwu Dang , Kay Chen Tan

We investigate a recently proposed model for cortical computation which performs relational inference. It consists of several interconnected, structurally equivalent populations of leaky integrate-and-fire (LIF) neurons, which are trained…

Neural and Evolutionary Computing · Computer Science 2017-03-21 Johannes Thiele , Peter Diehl , Matthew Cook

The stringent memory and power constraints required in edge-computing sensory-processing applications have made event-driven neuromorphic systems a promising technology. On-chip online learning provides such systems the ability to learn the…

Emerging Technologies · Computer Science 2022-01-26 Matteo Cartiglia , Arianna Rubino , Shyam Narayanan , Charlotte Frenkel , Germain Haessig , Giacomo Indiveri , Melika Payvand

Neural noise sets a limit to information transmission in sensory systems. In several areas, the spiking response (to a repeated stimulus) has shown a higher degree of regularity than predicted by a Poisson process. However, a simple model…

Neurons and Cognition · Quantitative Biology 2018-01-08 Ulisse Ferrari , Stephane Deny , Olivier Marre , Thierry Mora

Spike sorting is an essential process in neural recording, which identifies and separates electrical signals from individual neurons recorded by electrodes in the brain, enabling researchers to study how specific neurons communicate and…

Neurons and Cognition · Quantitative Biology 2025-12-23 Yimu Zhang , Dongqi Han , Yansen Wang , Zhenning Lv , Yu Gu , Dongsheng Li

Neurophysiologists are nowadays able to record from a large number of extracellular electrodes and to extract, from the raw data, the sequences of action potentials or spikes generated by many neurons. Unfortunately these ''many neurons''…

Applications · Statistics 2026-04-22 Pierre Charitat , Ségolen Geffray , Christophe Pouzat

This study explores the design and control of the behaviour of agents and robots using simple circuits of spiking neurons and Spike Timing Dependent Plasticity (STDP) as a mechanism of associative and unsupervised learning. Based on a…

Robotics · Computer Science 2015-09-25 Cristian Jimenez-Romero , David Sousa-Rodrigues , Jeffrey H. Johnson

Sparse sensor placement is a central challenge in the efficient characterization of complex systems when the cost of acquiring and processing data is high. Leading sparse sensing methods typically exploit either spatial or temporal…

Optimization and Control · Mathematics 2022-06-08 Thomas L. Mohren , Thomas L. Daniel , Steven L. Brunton , Bingni W. Brunton

The characterization of network and biophysical properties from neural spiking activity is an important goal in neuroscience. A framework that provides unbiased inference on causal synaptic interaction and single neural properties has been…

Neurons and Cognition · Quantitative Biology 2024-05-27 Kevin S. Chen , Ying-Jen Yang