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Explainable AI (XAI) is an active research area to interpret a neural network's decision by ensuring transparency and trust in the task-specified learned models. Recently, perturbation-based model analysis has shown better interpretation,…

Computer Vision and Pattern Recognition · Computer Science 2021-02-17 Mahesh Sudhakar , Sam Sattarzadeh , Konstantinos N. Plataniotis , Jongseong Jang , Yeonjeong Jeong , Hyunwoo Kim

Modern AI systems frequently rely on opaque black-box models, most notably Deep Neural Networks, whose performance stems from complex architectures with millions of learned parameters. While powerful, their complexity poses a major…

Machine Learning · Computer Science 2026-02-23 David Dembinsky , Adriano Lucieri , Stanislav Frolov , Hiba Najjar , Ko Watanabe , Andreas Dengel

Advancements in high-throughput technologies have led to a shift from traditional hypothesis-driven methodologies to data-driven approaches. Multi-omics refers to the integrative analysis of data derived from multiple 'omes', such as…

Genomics · Quantitative Biology 2024-10-17 Ahmad Hussein , Mukesh Prasad , Ali Braytee

The rationale behind a deep learning model's output is often difficult to understand by humans. EXplainable AI (XAI) aims at solving this by developing methods that improve interpretability and explainability of machine learning models.…

Artificial Intelligence · Computer Science 2023-08-08 Rafaël Brandt , Daan Raatjens , Georgi Gaydadjiev

Explainable Artificial Intelligence (XAI) has emerged as a critical tool for interpreting the predictions of complex deep learning models. While XAI has been increasingly applied in various domains within acoustics, its use in bioacoustics,…

Sound · Computer Science 2025-09-11 Zubair Faruqui , Mackenzie S. McIntire , Rahul Dubey , Jay McEntee

Deep learning models show significant potential for advancing AI-assisted medical diagnostics, particularly in detecting lung cancer through medical image modalities such as chest X-rays. However, the black-box nature of these models poses…

Machine Learning · Computer Science 2025-03-31 Amy Rafferty , Rishi Ramaesh , Ajitha Rajan

Explainable AI (XAI) is a necessity in safety-critical systems such as in clinical diagnostics due to a high risk for fatal decisions. Currently, however, XAI resembles a loose collection of methods rather than a well-defined process. In…

Computer Vision and Pattern Recognition · Computer Science 2022-07-12 Lukas Klein , Mennatallah El-Assady , Paul F. Jäger

Existing artificial intelligence (AI) models for diagnosing knee osteoarthritis (OA) have faced criticism for their lack of transparency and interpretability, despite achieving medical-expert-like performance. This opacity makes them…

Machine Learning · Computer Science 2023-08-21 Yun Xin Teoh , Alice Othmani , Siew Li Goh , Juliana Usman , Khin Wee Lai

EXplainable Artificial Intelligence (XAI) aims to help users to grasp the reasoning behind the predictions of an Artificial Intelligence (AI) system. Many XAI approaches have emerged in recent years. Consequently, a subfield related to the…

Explainable Artificial Intelligence (XAI) plays a crucial role in enabling human understanding and trust in deep learning systems. As models get larger, more ubiquitous, and pervasive in aspects of daily life, explainability is necessary to…

Machine Learning · Computer Science 2024-05-29 Vinitra Swamy , Jibril Frej , Tanja Käser

Recent years have seen important advances in the quality of state-of-the-art models, but this has come at the expense of models becoming less interpretable. This survey presents an overview of the current state of Explainable AI (XAI),…

Computation and Language · Computer Science 2025-04-16 Marina Danilevsky , Kun Qian , Ranit Aharonov , Yannis Katsis , Ban Kawas , Prithviraj Sen

An explainable AI (XAI) model aims to provide transparency (in the form of justification, explanation, etc) for its predictions or actions made by it. Recently, there has been a lot of focus on building XAI models, especially to provide…

Human-Computer Interaction · Computer Science 2022-01-11 Arjun Akula , Song-Chun Zhu

Across various sectors applications of eXplainableAI (XAI) gained momentum as the increasing black-boxedness of prevailing Machine Learning (ML) models became apparent. In parallel, Large Language Models (LLMs) significantly developed in…

Computation and Language · Computer Science 2025-05-07 Jonas Bokstaller , Julia Altheimer , Julian Dormehl , Alina Buss , Jasper Wiltfang , Johannes Schneider , Maximilian Röglinger

Why do explainable AI (XAI) explanations in radiology, despite their promise of transparency, still fail to gain human trust? Current XAI approaches provide justification for predictions, however, these do not meet practitioners' needs.…

Human-Computer Interaction · Computer Science 2023-04-10 Robert Kaufman , David Kirsh

This paper explores the significant impact of AI-based medical devices, including wearables, telemedicine, large language models, and digital twins, on clinical decision support systems. It emphasizes the importance of producing outcomes…

Artificial Intelligence · Computer Science 2024-04-11 Elham Nasarian , Roohallah Alizadehsani , U. Rajendra Acharya , Kwok-Leung Tsui

Background: Despite the current ubiquity of Large Language Models (LLMs) across the medical domain, there is a surprising lack of studies which address their reasoning behaviour. We emphasise the importance of understanding reasoning…

Computation and Language · Computer Science 2025-07-29 Shamus Sim , Tyrone Chen

As autonomous technologies increasingly shape maritime operations, understanding why an AI system makes a decision becomes as crucial as what it decides. In complex and dynamic maritime environments, trust in AI depends not only on…

Artificial Intelligence · Computer Science 2025-09-19 Doreen Jirak , Pieter Maes , Armeen Saroukanoff , Dirk van Rooy

Explainability domain generalization and rare class reliability are critical challenges in medical AI where deep models often fail under real world distribution shifts and exhibit bias against infrequent clinical conditions This paper…

Artificial Intelligence · Computer Science 2026-01-06 Midhat Urooj , Ayan Banerjee , Sandeep Gupta

Deployments of artificial intelligence in medical diagnostics mandate not just accuracy and efficacy but also trust, emphasizing the need for explainability in machine decisions. The recent trend in automated medical image diagnostics leans…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Ugur Demir , Debesh Jha , Zheyuan Zhang , Elif Keles , Bradley Allen , Aggelos K. Katsaggelos , Ulas Bagci

This paper explores the journey of AI in finance, with a particular focus on the crucial role and potential of Explainable AI (XAI). We trace AI's evolution from early statistical methods to sophisticated machine learning, highlighting…

Statistical Finance · Quantitative Finance 2023-06-06 Barry Quinn