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Contemporary large language models (LLMs) may have utility for processing unstructured, narrative free-text clinical data contained in electronic health records (EHRs) -- a particularly important use-case for mental health where a majority…

Artificial Intelligence · Computer Science 2024-04-01 Niall Taylor , Andrey Kormilitzin , Isabelle Lorge , Alejo Nevado-Holgado , Dan W Joyce

Many real-world Electronic Health Record (EHR) data contains a large proportion of missing values. Leaving substantial portion of missing information unaddressed usually causes significant bias, which leads to invalid conclusion to be…

Machine Learning · Computer Science 2020-11-04 Lucas J. Liu , Hongwei Zhang , Jianzhong Di , Jin Chen

The breadth, scale, and temporal granularity of modern electronic health records (EHR) systems offers great potential for estimating personalized and contextual patient health trajectories using sequential deep learning. However, learning…

Electronic Health Records (EHRs) contain rich, longitudinal patient information across structured (e.g., labs, vitals, and imaging) and unstructured (e.g., clinical notes) modalities. While deep learning models such as RNNs and Transformers…

Machine Learning · Computer Science 2026-02-18 Mohammad Al Olaimat , Shaika Chowdhury , Serdar Bozdag

The increase in availability of longitudinal electronic health record (EHR) data is leading to improved understanding of diseases and discovery of novel phenotypes. The majority of clustering algorithms focus only on patient trajectories,…

Machine Learning · Computer Science 2021-11-12 Oliver Carr , Avelino Javer , Patrick Rockenschaub , Owen Parsons , Robert Dürichen

Large language models (LLMs) have achieved unprecedented performances in various applications, yet evaluating them is still challenging. Existing benchmarks are either manually constructed or are automatic, but lack the ability to evaluate…

Computation and Language · Computer Science 2024-11-05 Jio Oh , Soyeon Kim , Junseok Seo , Jindong Wang , Ruochen Xu , Xing Xie , Steven Euijong Whang

The rise of electronic health records (EHRs) has unlocked new opportunities for medical research, but privacy regulations and data heterogeneity remain key barriers to large-scale machine learning. Federated learning (FL) enables…

Machine Learning · Computer Science 2025-05-27 Natallia Kokash , Lei Wang , Thomas H. Gillespie , Adam Belloum , Paola Grosso , Sara Quinney , Lang Li , Bernard de Bono

Electrocardiography (ECG) is a non-invasive tool for predicting cardiovascular diseases (CVDs). Current ECG-based diagnosis systems show promising performance owing to the rapid development of deep learning techniques. However, the label…

Signal Processing · Electrical Eng. & Systems 2023-06-21 Rushuang Zhou , Lei Lu , Zijun Liu , Ting Xiang , Zhen Liang , David A. Clifton , Yining Dong , Yuan-Ting Zhang

Electronic healthcare records (EHR) contain a huge wealth of data that can support the prediction of clinical outcomes. EHR data is often stored and analysed using clinical codes (ICD10, SNOMED), however these can differ across registries…

Machine Learning · Computer Science 2024-12-03 Elizabeth Remfry , Rafael Henkin , Michael R Barnes , Aakanksha Naik

Embedding algorithms are increasingly used to represent clinical concepts in healthcare for improving machine learning tasks such as clinical phenotyping and disease prediction. Recent studies have adapted state-of-the-art bidirectional…

Machine Learning · Computer Science 2021-12-07 Chao Pang , Xinzhuo Jiang , Krishna S Kalluri , Matthew Spotnitz , RuiJun Chen , Adler Perotte , Karthik Natarajan

Large language models (LLMs) have demonstrated exceptional capabilities in planning and tool utilization as autonomous agents, but few have been developed for medical problem-solving. We propose EHRAgent, an LLM agent empowered with a code…

Computation and Language · Computer Science 2024-10-07 Wenqi Shi , Ran Xu , Yuchen Zhuang , Yue Yu , Jieyu Zhang , Hang Wu , Yuanda Zhu , Joyce Ho , Carl Yang , May D. Wang

Much of biomedical and healthcare data is encoded in discrete, symbolic form such as text and medical codes. There is a wealth of expert-curated biomedical domain knowledge stored in knowledge bases and ontologies, but the lack of reliable…

Artificial Intelligence · Computer Science 2020-06-25 David Chang , Ivana Balazevic , Carl Allen , Daniel Chawla , Cynthia Brandt , Richard Andrew Taylor

Information in electronic health records (EHR), such as clinical narratives, examination reports, lab measurements, demographics, and other patient encounter entries, can be transformed into appropriate data representations that can be used…

Machine Learning · Computer Science 2019-09-23 Wei-Hung Weng , Peter Szolovits

Electronic health records (EHRs) are designed to synthesize diverse data types, including unstructured clinical notes, structured lab tests, and time-series visit data. Physicians draw on these multimodal and temporal sources of EHR data to…

The continuous evolution of system specifications necessitates frequent evaluation of conflicting requirements, a process that is traditionally labour intensive. Although large language models (LLMs) have demonstrated significant potential…

Software Engineering · Computer Science 2026-03-26 Shreyas Patil , Pragati Kumari , Novarun Deb , Gouri Ginde

Link prediction is a cornerstone of the Web ecosystem, powering applications from recommendation and search to knowledge graph completion and collaboration forecasting. However, large-scale networks present unique challenges: they contain…

Social and Information Networks · Computer Science 2026-01-29 Zhejian Yang , Songwei Zhao , Zilin Zhao , Hechang Chen

Recently, there is great interest to investigate the application of deep learning models for the prediction of clinical events using electronic health records (EHR) data. In EHR data, a patient's history is often represented as a sequence…

Machine Learning · Computer Science 2021-10-05 Laila Rasmy , Jie Zhu , Zhiheng Li , Xin Hao , Hong Thoai Tran , Yujia Zhou , Firat Tiryaki , Yang Xiang , Hua Xu , Degui Zhi

The widespread adoption of electronic health records has created new opportunities for translational clinical research, yet this promise remains constrained by fragmented data across privacy-siloed institutions and substantial heterogeneity…

Despite the growing availability of Electronic Health Record (EHR) data, researchers often face substantial barriers in effectively using these data for translational research due to their complexity, heterogeneity, and lack of standardized…

Foundation models hold promise for transforming AI in healthcare by providing modular components that are easily adaptable to downstream healthcare tasks, making AI development more scalable and cost-effective. Structured EHR foundation…

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