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Diagnosis of a clinical condition is a challenging task, which often requires significant medical investigation. Previous work related to diagnostic inferencing problems mostly consider multivariate observational data (e.g. physiological…

Computation and Language · Computer Science 2017-01-05 Aaditya Prakash , Siyuan Zhao , Sadid A. Hasan , Vivek Datla , Kathy Lee , Ashequl Qadir , Joey Liu , Oladimeji Farri

Clinical trials are a systematic endeavor to assess the safety and efficacy of new drugs or treatments. Conducting such trials typically demands significant financial investment and meticulous planning, highlighting the need for accurate…

Machine Learning · Computer Science 2025-11-03 Tien Huu Do , Antoine Masquelier , Nae Eoun Lee , Jonathan Crowther

We propose a novel way to incorporate expert knowledge into the training of deep neural networks. Many approaches encode domain constraints directly into the network architecture, requiring non-trivial or domain-specific engineering. In…

Machine Learning · Computer Science 2021-11-03 Nicholas Hoernle , Rafael Michael Karampatsis , Vaishak Belle , Kobi Gal

Medication recommendation aims to integrate patients' long-term health records to provide accurate and safe medication combinations for specific health states. Existing methods often fail to deeply explore the true causal relationships…

Information Retrieval · Computer Science 2024-10-31 Shunpan Liang , Xiang Li , Shi Mu , Chen Li , Yu Lei , Yulei Hou , Tengfei Ma

Early detection of skin cancers like melanoma is crucial to ensure high chances of survival for patients. Clinical application of Deep Learning (DL)-based Decision Support Systems (DSS) for skin cancer screening has the potential to improve…

Computer Vision and Pattern Recognition · Computer Science 2021-03-10 Adriano Lucieri , Andreas Dengel , Sheraz Ahmed

Dementia is under-recognized in the community, under-diagnosed by healthcare professionals, and under-coded in claims data. Information on cognitive dysfunction, however, is often found in unstructured clinician notes within medical records…

Large language models (LLMs) holds significant promise in achieving general medication recommendation systems owing to their comprehensive interpretation of clinical notes and flexibility to medication encoding. We evaluated both…

Information Retrieval · Computer Science 2025-08-05 Zihao Zhao , Chenxiao Fan , Junlong Liu , Zheng Wang , Xiangnan He , Chongming Gao , Juan Li , Fuli Feng

Prognostic task is of great importance as it closely related to the survival analysis of patients, the optimization of treatment plans and the allocation of resources. The existing prognostic models have shown promising results on specific…

Image and Video Processing · Electrical Eng. & Systems 2025-01-14 Binyu Zhang , Shichao Li , Junpeng Jian , Zhu Meng , Limei Guo , Zhicheng Zhao

Drug repurposing is often framed as a candidate identification task, but existing approaches provide limited guidance for distinguishing biologically plausible candidates from historically well-connected ones. Here we introduce DrugKLM, a…

The role of Artificial Intelligence (AI) is growing in every stage of drug development. Nevertheless, a major challenge in drug discovery AI remains: Drug pharmacokinetic (PK) and Drug-Target Interaction (DTI) datasets collected in…

Quantitative Methods · Quantitative Biology 2025-10-27 Bing Hu , Jong-Hoon Park , Helen Chen , Young-Rae Cho , Anita Layton

We propose a representation learning framework for medical diagnosis domain. It is based on heterogeneous network-based model of diagnostic data as well as modified metapath2vec algorithm for learning latent node representation. We compare…

Machine Learning · Computer Science 2020-01-24 Karol Antczak

Pre-trained transformer language models (LMs) have in recent years become the dominant paradigm in applied NLP. These models have achieved state-of-the-art performance on tasks such as information extraction, question answering, sentiment…

Computation and Language · Computer Science 2025-04-14 Aidan Mannion , Thierry Chevalier , Didier Schwab , Lorraine Geouriot

A key component of deep learning (DL) for natural language processing (NLP) is word embeddings. Word embeddings that effectively capture the meaning and context of the word that they represent can significantly improve the performance of…

Taking medicines is a fundamental aspect to cure illnesses. However, studies have shown that it can be hard for patients to remember the correct posology. More aggravating, a wrong dosage generally causes the disease to worsen. Although,…

Computer Vision and Pattern Recognition · Computer Science 2022-03-29 Danilo Avola , Luigi Cinque , Alessio Fagioli , Gian Luca Foresti , Marco Raoul Marini , Alessio Mecca , Daniele Pannone

Despite the growing use of Electronic Health Records (EHR) for AI-assisted diagnosis prediction, most data-driven models struggle to incorporate clinically meaningful medical knowledge. They often rely on limited ontologies, lacking…

Machine Learning · Computer Science 2025-04-17 Pengfei Hu , Chang Lu , Fei Wang , Yue Ning

Digital health interventions (DHIs) and remote patient monitoring (RPM) have shown great potential in improving chronic disease management through personalized care. However, barriers like limited efficacy and workload concerns hinder…

Machine Learning · Computer Science 2025-12-23 Johannes O. Ferstad , Emily B. Fox , David Scheinker , Ramesh Johari

Deep Learning has emerged as a promising approach for skin lesion analysis. However, existing methods mostly rely on fully supervised learning, requiring extensive labeled data, which is challenging and costly to obtain. To alleviate this…

Image and Video Processing · Electrical Eng. & Systems 2025-08-18 Siyamalan Manivannan

Incorporating a human-in-the-loop system when deploying automated decision support is critical in healthcare contexts to create trust, as well as provide reliable performance on a patient-to-patient basis. Deep learning methods while having…

Machine Learning · Computer Science 2020-08-26 Nabeel Seedat

The precise subtype classification of myeloproliferative neoplasms (MPNs) based on multimodal information, which assists clinicians in diagnosis and long-term treatment plans, is of great clinical significance. However, it remains a great…

Image and Video Processing · Electrical Eng. & Systems 2024-07-12 Yuan Zhang , Yaolei Qi , Xiaoming Qi , Yongyue Wei , Guanyu Yang

With the advancements in computer technology, there is a rapid development of intelligent systems to understand the complex relationships in data to make predictions and classifications. Artificail Intelligence based framework is rapidly…

Machine Learning · Computer Science 2021-07-30 G Jignesh Chowdary , Suganya G , Premalatha M , Asnath Victy Phamila Y , Karunamurthy K