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We propose a novel and unified method, measurement-conditioned denoising diffusion probabilistic model (MC-DDPM), for under-sampled medical image reconstruction based on DDPM. Different from previous works, MC-DDPM is defined in measurement…

Image and Video Processing · Electrical Eng. & Systems 2022-03-09 Yutong Xie , Quanzheng Li

Diffusion models have demonstrated significant potential in producing high-quality images in medical image translation to aid disease diagnosis, localization, and treatment. Nevertheless, current diffusion models have limited success in…

Image and Video Processing · Electrical Eng. & Systems 2024-11-26 Yunxiang Li , Hua-Chieh Shao , Xiaoxue Qian , You Zhang

Computed tomography (CT) equivalent information is needed for attenuation correction in PET imaging and for dose planning in radiotherapy. Prior work has shown that Gaussian mixture models can be used to generate a substitute CT (s-CT)…

Applications · Statistics 2016-09-29 Anders Hildeman , David Bolin , Jonas Wallin , Adam Johansson , Tufve Nyholm , Thomas Asklund , Jun Yu

Model-based treatment planning for transcranial ultrasound therapy typically involves mapping the acoustic properties of the skull from an x-ray computed tomography (CT) image of the head. Here, three methods for generating pseudo-CT images…

Medical imaging applications are highly specialized in terms of human anatomy, pathology, and imaging domains. Therefore, annotated training datasets for training deep learning applications in medical imaging not only need to be highly…

Computer Vision and Pattern Recognition · Computer Science 2024-09-10 Arjun Krishna , Ge Wang , Klaus Mueller

Cone-beam computed tomography (CBCT) is widely used for image-guided radiotherapy (IGRT). It provides real time visualization at low cost and dose. However, photon scattering and beam hindrance cause artifacts in CBCT. These include…

Medical Physics · Physics 2025-09-29 Alzahra Altalib , Chunhui Li , Alessandro Perelli

The dose of X-ray radiation and the scanning time are crucial factors in computed tomography (CT) for clinical applications. In this work, we introduce a multi-source static CT imaging system designed to rapidly acquire sparse view and…

Medical Physics · Physics 2025-01-03 Ziju Shen , Haimiao Zhang , Bin Dong , Jun Qiu , Yunxiang Li , Zhili Cui

With the rapid development of artificial intelligence (AI), AI-assisted medical imaging analysis demonstrates remarkable performance in early lung cancer screening. However, the costly annotation process and privacy concerns limit the…

Image and Video Processing · Electrical Eng. & Systems 2025-08-14 Yifan Jiang , Yannick Lemaréchal , Sophie Plante , Josée Bafaro , Jessica Abi-Rjeile , Philippe Joubert , Philippe Després , Venkata Manem

With substantial public concerns on potential cancer risks and health hazards caused by the accumulated radiation exposure in medical imaging, reducing radiation dose in X-ray based medical imaging such as Computed Tomography Perfusion…

Image and Video Processing · Electrical Eng. & Systems 2019-10-21 Peng Liu , Ruogu Fang

Segmentation masks of pathological areas are useful in many medical applications, such as brain tumour and stroke management. Moreover, healthy counterfactuals of diseased images can be used to enhance radiologists' training files and to…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Alessandro Fontanella , Grant Mair , Joanna Wardlaw , Emanuele Trucco , Amos Storkey

Purpose: This study aims to develop and evaluate a three channel denoising diffusion probabilistic model (DDPM) for synthesizing single breast dual view mammograms and to assess the impact of channel representations on image fidelity and…

Performing magnetic resonance imaging (MRI) reconstruction from under-sampled k-space data can accelerate the procedure to acquire MRI scans and reduce patients' discomfort. The reconstruction problem is usually formulated as a denoising…

Image and Video Processing · Electrical Eng. & Systems 2023-12-11 Tianqi Xiang , Wenjun Yue , Yiqun Lin , Jiewen Yang , Zhenkun Wang , Xiaomeng Li

The resurgence of deep neural networks has created an alternative pathway for low-dose computed tomography denoising by learning a nonlinear transformation function between low-dose CT (LDCT) and normal-dose CT (NDCT) image pairs. However,…

Image and Video Processing · Electrical Eng. & Systems 2022-11-04 Sutanu Bera , Prabir Kumar Biswas

Accurate targeting is critical for the effectiveness of transcranial focused ultrasound (tFUS) neuromodulation. While CT provides accurate skull acoustic properties, its ionizing radiation and poor soft tissue contrast limit clinical…

Medical Physics · Physics 2025-07-14 Hengyu Gao , Shaodong Ding , Ziyang Liu , Jiefu Zhang , Bolun Li , Zhiwu An , Li Wang , Jing Jing , Tao Liu , Yubo Fan , Zhongtao Hu

Generating synthetic CT (sCT) from MRI or CBCT plays a crucial role in enabling MRI-only and CBCT-based adaptive radiotherapy, improving treatment precision while reducing patient radiation exposure. To address this task, we adopt a fully…

Computer Vision and Pattern Recognition · Computer Science 2026-04-24 Arnela Hadzic , Simon Johannes Joham , Martin Urschler

Sparse views X-ray computed tomography has emerged as a contemporary technique to mitigate radiation dose. Because of the reduced number of projection views, traditional reconstruction methods can lead to severe artifacts. Recently,…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Liutao Yang , Jiahao Huang , Guang Yang , Daoqiang Zhang

This study explores the use of text-prompted MRI image generation with the Stable Diffusion (SD) model to address challenges in acquiring real MRI datasets, such as high costs, limited rare case samples, and privacy concerns. The SD model,…

Image and Video Processing · Electrical Eng. & Systems 2025-05-30 Xinxian Fan , Mengye Lyu

Positron Emission Tomography (PET) imaging requires accurate attenuation correction (AC) to account for photon loss due to tissue density variations. In PET/MR systems, computed tomography (CT), which offers a straightforward estimation of…

Image and Video Processing · Electrical Eng. & Systems 2025-04-11 Weijie Chen , James Wang , Alan McMillan

To enable magnetic resonance (MR)-only radiotherapy and facilitate modelling of radiation attenuation in humans, synthetic-CT (sCT) images need to be generated. Considering the application of MR-guided radiotherapy and online adaptive…

The generation of Synthetic Computed Tomography (sCT) images has become a pivotal methodology in modern clinical practice, particularly in the context of Radiotherapy (RT) treatment planning. The use of sCT enables the calculation of doses,…