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Background: The treatment of depressive episodes is well established, with clearly demonstrated effectiveness of antidepressants and psychotherapies. However, more than one-third of depressed patients do not respond to treatment.…

Neurons and Cognition · Quantitative Biology 2024-03-29 Sébastien Dam , Jean-Marie Batail , Gabriel H Robert , Dominique Drapier , Pierre Maurel , Julie Coloigner

Multiple-subject network data are fast emerging in recent years, where a separate connectivity matrix is measured over a common set of nodes for each individual subject, along with subject covariates information. In this article, we propose…

Methodology · Statistics 2021-03-23 Jingfei Zhang , Will Wei Sun , Lexin Li

We develop a framework to track the structure of temporal networks with a signal processing approach. The method is based on the duality between networks and signals using a multidimensional scaling technique. This enables a study of the…

Social and Information Networks · Computer Science 2015-05-13 Ronan Hamon , Pierre Borgnat , Patrick Flandrin , Céline Robardet

This paper concerns the modeling of multi-way functional data where double or multiple indices are involved. We introduce a concept of weak separability. The weakly separable structure supports the use of factorization methods that…

Methodology · Statistics 2018-11-15 Brian Lynch , Kehui Chen

The human neocortex is functionally organised at its highest level along a continuous sensory-to-association (AS) hierarchy. This study characterises the AS hierarchy of patients with schizophrenia in a comparison with controls. Using a…

Neurons and Cognition · Quantitative Biology 2025-11-06 Subati Abulikemu , Puria Radmard , Michail Mamalakis , John Suckling

The anatomical structure of the brain can be observed via non-invasive techniques such as diffusion imaging. However, these are imperfect because they miss connections that are actually known to exist, especially long range…

Neurons and Cognition · Quantitative Biology 2015-02-25 Somwrita Sarkar , Sanjay Chawla , Donna Xu

Measures of linear dependence (coherence) and nonlinear dependence (phase synchronization) between any number of multivariate time series are defined. The measures are expressed as the sum of lagged dependence and instantaneous dependence.…

Methodology · Statistics 2007-11-12 Roberto D. Pascual-Marqui

Brain science is an evolving research area inviting great enthusiasm with its potential for providing insights and thereby, preventing, and treating multiple neuronal disorders affecting millions of patients. Discovery of relationships,…

Neurons and Cognition · Quantitative Biology 2016-03-17 Bisakha Ray , Alexander V. Alekseyenko , Sisi Ma , Alexander Statnikov , Constantin Aliferis

Schizophrenia is a severe mental health condition that requires a long and complicated diagnostic process. However, early diagnosis is vital to control symptoms. Deep learning has recently become a popular way to analyse and interpret…

Machine Learning · Computer Science 2022-04-01 Daniel Organisciak , Hubert P. H. Shum , Ephraim Nwoye , Wai Lok Woo

Brain connectivity analysis based on magnetic resonance imaging is crucial for understanding neurological mechanisms. However, edge-based connectivity inference faces significant challenges, particularly the curse of dimensionality when…

Methodology · Statistics 2025-12-23 Zijing Li , Chenhao Zeng , Shufei Ge

This paper describes an approach of using dynamic Structural Equation Modeling (SEM) analysis to estimate the connectivity networks from resting-state fMRI data measured by a multiband EPI sequence. Two structural equation models were…

Neurons and Cognition · Quantitative Biology 2017-04-03 Jiancheng Zhuang

We propose a novel optimization framework to predict clinical severity from resting state fMRI (rs-fMRI) data. Our model consists of two coupled terms. The first term decomposes the correlation matrices into a sparse set of representative…

Neurons and Cognition · Quantitative Biology 2024-11-25 Niharika Shimona D'Souza , Mary Beth Nebel , Nicholas Wymbs , Stewart H. Mostofsky , Archana Venkataraman

Schizophrenia is a serious psychiatric disorder. Its pathogenesis is not completely clear, making it difficult to treat patients precisely. Because of the complicated non-Euclidean network structure of the human brain, learning critical…

Computer Vision and Pattern Recognition · Computer Science 2024-08-28 Yuhong Jiao , Jiaqing Miao , Jinnan Gong , Hui He , Ping Liang , Cheng Luo , Ying Tan

The entrainment between weakly-coupled nonlinear oscillators, as well as between complex signals such as those representing physiological activity, is frequently assessed in terms of whether a stable relationship is detectable between the…

Neurons and Cognition · Quantitative Biology 2019-02-27 Ludovico Minati , Natsue Yoshimura , Mattia Frasca , Stanislaw Drozdz , Yasuharu Koike

Complex networks often exhibit emergent behaviors, where simple dyadic interactions yield collective dynamics that cannot be explained by examining the system's units individually or in pairs. Understanding how redundant and synergistic…

Residual connections are central to modern deep learning architectures, enabling the training of very deep networks by mitigating gradient vanishing. Hyper-Connections recently generalized residual connections by introducing multiple…

Machine Learning · Computer Science 2025-03-19 Defa Zhu , Hongzhi Huang , Jundong Zhou , Zihao Huang , Yutao Zeng , Banggu Wu , Qiyang Min , Xun Zhou

Redundancy is a ubiquitous property of the nervous system. This means that vastly different configurations of cellular and synaptic components can enable the same neural circuit functions. However, until recently very little brain disorder…

Neurons and Cognition · Quantitative Biology 2021-02-08 Beatriz E. P. Mizusaki , Cian O'Donnell

Financial spillovers in interconnected systems, such as global banking networks, require tools that capture temporal and frequency dynamics, while incorporating the underlying network topology. While current network time series models are…

Methodology · Statistics 2026-04-07 Cristian F. Jiménez-Varón , Marina I. Knight

In increasingly many settings, data sets consist of multiple samples from a population of networks, with vertices aligned across these networks. For example, brain connectivity networks in neuroscience consist of measures of interaction…

Statistics Theory · Mathematics 2021-05-11 Keith Levin , Asad Lodhia , Elizaveta Levina

Complex functional brain networks are large networks of brain regions and functional brain connections. Statistical characterizations of these networks aim to quantify global and local properties of brain activity with a small number of…

Neurons and Cognition · Quantitative Biology 2011-07-19 Mikail Rubinov , Olaf Sporns
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