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In this work, we used a coupled level set and volume of fluid (CLSVOF) computational method for studying the generation of microdroplets in a two dimensional circular co-flow microfluidic device. The fundamental understanding of shear…

Fluid Dynamics · Physics 2025-07-17 Manohar Jammula , Somasekhara Goud Sontti

Droplet-based microfluidics systems have become widely used in recent years thanks to their advantages, varying from the possibility of handling small fluid volumes to directly synthesizing and encapsulating various living forms for…

This study investigates the hydrodynamics of droplet formation in a T-shaped cylindrical microfluidic device using micro-PIV experiments and CFD simulations. Devices of 150 micro-m internal diameter were fabricated from PDMS via a…

Fluid Dynamics · Physics 2026-03-04 Pratibha Dogra , Ram Prakash Bharti , Gaurav Sharma

Ultrasound-vaporizable microdroplets can be exploited for targeted drug delivery. However, it requires customized microfluidic techniques able to produce monodisperse, capillary-sized and biocompatible multiple emulsions. Recent development…

Soft Condensed Matter · Physics 2019-12-17 E. Teston , V. Hingot , V. Faugeras , C. Errico , M. Bezagu , M. Tanter , O. Couture

The generation of microdroplets via segmentation in microfluidic devices is of interest in many applications, from biochemical to pharmaceutical. This technique permits indeed much higher control on the droplet size, uniformity and…

Fluid Dynamics · Physics 2026-01-15 Alessio Innocenti , Andrea Poggi , Simone Camarri , Maria Vittoria Salvetti

Droplet microfluidics are a powerful approach for hydrogel cell encapsulations. Much of the field has focused on single-cell encapsulations with pico-nanoliter droplet volumes necessary for single-cell sequencing or high-throughput…

In this article, we have developed a computational model to determine the droplet formation regime and its transition in a square microfluidic flow-focusing device that eventually dictate the droplet shape, size, and its formation…

Fluid Dynamics · Physics 2025-10-28 Somasekhara Goud Sontti , Arnab Atta

Precise control of multiphase microfluidic flows underpins applications ranging from chemical processing to biomedical diagnostics. We investigate the response of a liquid--liquid coflow in a rectangular microchannel to an externally…

Fluid Dynamics · Physics 2026-04-08 D. Ghosh , S. Z. Hoque , T. Sujith , N. S. Satpathi , L. Malik , A. K. Sen

Scalable technologies for the production of bio-compatible complex microfibers with controllable size and composition at competitively high throughput are urgently needed in order to meet the growing demand for such microstructures in…

Applied Physics · Physics 2022-08-11 Marangon Francesco , Baumgartner David , Planchette Carole

This review focuses on a microparticle-producing technique widely used for its efficacy in controlling physicochemical properties: droplet-based microfluidics. The review describes the various strategies applied under this technique, and…

Materials Science · Physics 2020-09-16 Cheng Zhang , Romain Grossier , Nadine Candoni , Stéphane Veesler

The hydrodynamics of droplets is significant in wide-ranging applications involving immiscible fluids and emulsions in food and pharmaceutical. The control and manipulation of droplets are primarily a function of flow governing and…

Fluid Dynamics · Physics 2022-01-19 Akepogu Venkateshwarlu , Ram Prakash Bharti

The production of monodisperse particles or droplets is a longstanding issue across various fields, from aerosol science to inkjet printing. In bioengineering, submillimeter cell laden hydrogel capsules have proven valuable for developing…

Fluid Dynamics · Physics 2025-03-28 Lucas Suire , Anirban Jana , Pierre Nassoy , Amaury Badon

Effective mixing is essential for biochemical reactions. In droplet-based microfluidics, immediate mixing of substances upon contact in the droplet formation stage can greatly enhance the uniformity of chemical reactions. Furthermore, it…

The growing demand for new microelectronic devices and pharmaceutical advancements has heightened interest in inkjet printing as a means of high-precision manufacturing technique. This study leverages data-driven analyses to optimize…

Fluid Dynamics · Physics 2025-01-24 Ali R. Hashemi , Angela M. Ares de Parga-Regalado , Pavel B. Ryzhakov

This study presents a three-dimensional transient computational fluid dynamics simulation of droplet generation in a flow-focusing microfluidic device using the Coupled Level Set and Volume of Fluid method for interface capturing. We…

Fluid Dynamics · Physics 2025-07-17 Manohar Jammula , Somasekhara Goud Sontti

We have developed a coupled level set and volume of fluid-based computational fluid dynamics model to analyze the droplet formation mechanism in a square flow-focusing microchannel. We demonstrate a flexible manipulation of droplet…

Fluid Dynamics · Physics 2025-10-09 Somasekhara Goud Sontti , Arnab Atta

In this Fluid Dynamics Videos submitted to the 31st Gallery of Fluid Motion, (find a different version here http://youtu.be/CS0c05WQ_js) we illustrate the special dynamics of capillary self-propelled Leidenfrost droplets in micrometric…

Fluid Dynamics · Physics 2013-10-23 Alvaro G. Marin , Daniel Arnaldo del Cerro , Gert-Willem Römer , Detlef Lohse

This work describes a new microfluidic device developed for rapid screening of solubility diagrams. In several parallel channels, hundreds of nanoliter-volume droplets of a given solution are first stored with a gradual variation in the…

Soft Condensed Matter · Physics 2007-05-23 P. Laval , N. Lisai , J. -B. Salmon , M. Joanicot

Recent works demonstrated that fiber arrays may constitue the basis of an open digital microfluidics. Various processes, such as droplet motion, fragmentation, trapping, release, mixing and encapsulation, may be achieved on fiber arrays.…

Fluid Dynamics · Physics 2015-03-13 Floriane Weyer , Marjorie Lismont , Laurent Dreesen , Nicolas Vandewalle

In this study, we present a two-stage method for fabricating monodisperse alginate hydrogel microspheres using a symmetrically designed flow-focusing microfluidic device. One of the flow-focusing junctions generates alginate hydrogel…

Chemical Physics · Physics 2024-12-04 Qing Qin , Yu Zhang , Yubei Wei , Jinnuo , Lv , Meiling Tian , Yuanyuan Sun , Xingjian , Huang , Jianglin Li , Yifeng , Su , Xiaoliang Xiang , Xing Hu , Zhizhi Zhou
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