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This report presents the comprehensive implementation, evaluation, and optimization of Denoising Diffusion Probabilistic Models (DDPMs) and Denoising Diffusion Implicit Models (DDIMs), which are state-of-the-art generative models. During…

Computer Vision and Pattern Recognition · Computer Science 2024-12-20 Jaineet Shah , Michael Gromis , Rickston Pinto

Denoising diffusion probabilistic models enable high-fidelity image synthesis and editing. In biomedicine, these models facilitate counterfactual image editing, producing pairs of images where one is edited to simulate hypothetical…

Image and Video Processing · Electrical Eng. & Systems 2024-07-23 Malek Ben Alaya , Daniel M. Lang , Benedikt Wiestler , Julia A. Schnabel , Cosmin I. Bercea

The generation of medical images presents significant challenges due to their high-resolution and three-dimensional nature. Existing methods often yield suboptimal performance in generating high-quality 3D medical images, and there is…

Image and Video Processing · Electrical Eng. & Systems 2025-12-02 Haoshen Wang , Zhentao Liu , Kaicong Sun , Xiaodong Wang , Dinggang Shen , Zhiming Cui

Healthy tissue inpainting has significant applications, including the generation of pseudo-healthy baselines for tumor growth models and the facilitation of image registration. In previous editions of the BraTS Local Synthesis of Healthy…

Image and Video Processing · Electrical Eng. & Systems 2025-07-18 Alicia Durrer , Florentin Bieder , Paul Friedrich , Bjoern Menze , Philippe C. Cattin , Florian Kofler

It can be challenging to identify brain MRI anomalies using supervised deep-learning techniques due to anatomical heterogeneity and the requirement for pixel-level labeling. Unsupervised anomaly detection approaches provide an alternative…

Image and Video Processing · Electrical Eng. & Systems 2023-08-30 Hasan Iqbal , Umar Khalid , Jing Hua , Chen Chen

Monitoring diseases that affect the brain's structural integrity requires automated analysis of magnetic resonance (MR) images, e.g., for the evaluation of volumetric changes. However, many of the evaluation tools are optimized for…

Objective: Cone-beam computed tomography (CBCT) provides a low-dose imaging alternative to conventional CT, but suffers from noise, scatter, and artifacts that degrade image quality. Synthetic CT (sCT) aims to translate CBCT to high-quality…

Medical Physics · Physics 2025-09-23 Alzahra Altalib , Chunhui Li , Alessandro Perelli

The scarcity of annotated surgical data poses a significant challenge for developing deep learning systems in computer-assisted interventions. While diffusion models can synthesize realistic images, they often suffer from data memorization,…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Danush Kumar Venkatesh , Stefanie Speidel

The integration of RGB and depth modalities significantly enhances the accuracy of segmenting complex indoor scenes, with depth data from RGB-D cameras playing a crucial role in this improvement. However, collecting an RGB-D dataset is more…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Xinhua Xu , Hong Liu , Jianbing Wu , Jinfu Liu

Interpreting EEG signals linked to spoken language presents a complex challenge, given the data's intricate temporal and spatial attributes, as well as the various noise factors. Denoising diffusion probabilistic models (DDPMs), which have…

Computation and Language · Computer Science 2023-11-15 Soowon Kim , Seo-Hyun Lee , Young-Eun Lee , Ji-Won Lee , Ji-Ha Park , Seong-Whan Lee

Diffusion models have shown impressive performance for generative modelling of images. In this paper, we present a novel semantic segmentation method based on diffusion models. By modifying the training and sampling scheme, we show that…

Computer Vision and Pattern Recognition · Computer Science 2021-12-28 Julia Wolleb , Robin Sandkühler , Florentin Bieder , Philippe Valmaggia , Philippe C. Cattin

Aside from offering state-of-the-art performance in medical image generation, denoising diffusion probabilistic models (DPM) can also serve as a representation learner to capture semantic information and potentially be used as an image…

Image and Video Processing · Electrical Eng. & Systems 2024-07-09 Chun-Mei Feng

Denoising Diffusion Probabilistic Models (DDPMs) can generate high-quality samples such as image and audio samples. However, DDPMs require hundreds to thousands of iterations to produce final samples. Several prior works have successfully…

Computer Vision and Pattern Recognition · Computer Science 2022-11-01 Luping Liu , Yi Ren , Zhijie Lin , Zhou Zhao

Diffusion Probabilistic Models (DPMs) have emerged as the de facto approach for high-fidelity image synthesis, operating diffusion processes on continuous VAE latent, which significantly differ from the text generation methods employed by…

Computer Vision and Pattern Recognition · Computer Science 2024-12-30 Xiaoping Wu , Jie Hu , Xiaoming Wei

Deep generative models have demonstrated remarkable success in medical image synthesis. However, ensuring conditioning faithfulness and high-quality synthetic images for direct or counterfactual generation remains a challenge. In this work,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-31 Fangrui Huang , Alan Wang , Binxu Li , Bailey Trang , Ridvan Yesiloglu , Tianyu Hua , Wei Peng , Ehsan Adeli

Artificial Intelligence (AI) based image analysis has an immense potential to support diagnostic histopathology, including cancer diagnostics. However, developing supervised AI methods requires large-scale annotated datasets. A potentially…

Semantic image synthesis aims to generate high-quality images given semantic conditions, i.e. segmentation masks and style reference images. Existing methods widely adopt generative adversarial networks (GANs). GANs take all conditional…

Computer Vision and Pattern Recognition · Computer Science 2024-08-21 Feng Liu , Xiaobin Chang

As deep learning-based, data-driven information extraction systems become increasingly integrated into modern document processing workflows, one primary concern is the risk of malicious leakage of sensitive private data from these systems.…

Cryptography and Security · Computer Science 2025-08-07 Saifullah Saifullah , Stefan Agne , Andreas Dengel , Sheraz Ahmed

Growing privacy concerns and regulations like GDPR and CCPA necessitate pseudonymization techniques that protect identity in image datasets. However, retaining utility is also essential. Traditional methods like masking and blurring degrade…

Computer Vision and Pattern Recognition · Computer Science 2024-12-10 Kartik Patwari , David Schneider , Xiaoxiao Sun , Chen-Nee Chuah , Lingjuan Lyu , Vivek Sharma

Hyperspectral images (HSI) have a large amount of spectral information reflecting the characteristics of matter, while their spatial resolution is low due to the limitations of imaging technology. Complementary to this are multispectral…

Image and Video Processing · Electrical Eng. & Systems 2023-07-10 Shuaikai Shi , Lijun Zhang , Jie Chen