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Bacteria such as Escherichia coli move about in a series of runs and tumbles: while a run state (straight motion) entails all the flagellar motors spinning in counterclockwise mode, a tumble is caused by a shift in the state of one or more…

Quantitative Methods · Quantitative Biology 2020-01-08 C. S. Renadheer , Ushasi Roy , Manoj Gopalakrishnan

This paper studies how patterns derived from a system of reaction-diffusion equations may vary significantly depending upon boundary and initial conditions, as well as in the spatial dependence of the coefficients involved. From an…

Subcellular Processes · Quantitative Biology 2016-01-06 Aldo Ledesma-Durán , Héctor Juárez-Valencia , Iván Santamaría-Holek

The reaction-diffusion models have been extensively applied to explain the mechanism of pattern formations in early embryogenesis based on geometrically confined microtissues consisting of human pluripotent stem cells. Recently, mechanical…

Biological Physics · Physics 2022-11-22 Tiankai Zhao , Hongyan Yuan

We develop numerical methods for reaction-diffusion systems based on the equations of fluctuating hydrodynamics (FHD). While the FHD formulation is formally described by stochastic partial differential equations (SPDEs), it becomes similar…

Fluid Dynamics · Physics 2018-01-17 Changho Kim , Andy Nonaka , John B. Bell , Alejandro L. Garcia , Aleksandar Donev

Cilia and flagella are hairlike organelles that propel cells through fluid. The active motion of the axoneme, the motile structure inside cilia and flagella, is powered by molecular motors of the dynein family. These motors generate forces…

Subcellular Processes · Quantitative Biology 2016-11-02 Pablo Sartori , Veikko Geyer , Jonathon Howard , Frank Jülicher

In this paper, we analyze the inverse dynamics and control of a bacteria-inspired uniflagellar robot in a fluid medium at low Reynolds number. Inspired by the mechanism behind the locomotion of flagellated bacteria, we consider a robot…

Robotics · Computer Science 2020-12-22 Mojtaba Forghani , Weicheng Huang , M. Khalid Jawed

Eukaryotic flagella are active structures with a complex architecture of microtubules, motor proteins and elastic links. They are capable of whiplike motions driven by motors sliding along filaments that are themselves constrained at an…

Soft Condensed Matter · Physics 2012-11-22 Raghunath Chelakkot , Arvind Gopinath , L. Mahadevan , Michael F. Hagan

We explore the locomotion of soft robots in granular medium (GM) resulting from the elastic deformation of slender rods. A low-cost, rapidly fabricable robot inspired by the physiological structure of bacteria is presented. It consists of a…

Robotics · Computer Science 2021-12-30 Yayun Du , Andrew Miller , M. Khalid Jawed

Reaction-diffusion systems have been proposed as a model for pattern formation and morphogenesis. The Fickian diffusion typically employed in these constructions model the Brownian motion of particles. The biological and chemical elements…

Quantitative Methods · Quantitative Biology 2023-11-09 Siddhartha Srivastava , Krishna Garikipati

A novel mechanism of reaction-induced active molecular motion, not involving any kind of self-propulsion, is proposed and analyzed. Because of the momentum exchange with the surrounding solvent, conformational transitions in…

Soft Condensed Matter · Physics 2023-04-19 Hiroyuki Kitahata , Alexander S. Mikhailov

The reaction-diffusion waves of proteins are known to be involved in fundamental cellular functions, such as cell migration, cell division, and vesicular transportation. In some of these phenomena, pattern formation on the membranes is…

Soft Condensed Matter · Physics 2021-07-16 Naoki Tamemoto , Hiroshi Noguchi

Although the auger-like 'swimming' motility of the African trypanosome was described upon its discovery over one hundred years ago, the precise biomechanical and biophysical properties of trypanosome flagellar motion has not been…

Biological Physics · Physics 2016-09-08 D. Fry , N. Hutchings , A. Ludu

Biological systems are robust to perturbations at both the genetic and environmental levels. Yet, these same perturbations can elicit variation in behavior. The interplay between functional robustness and behavioral variability is…

Biological Physics · Physics 2021-06-03 Veikko Geyer , Jonathon Howard , Pablo Sartori

The bacterial flagellar motor drives the rotation of flagellar filaments and enables many species of bacteria to swim. Torque is generated by interaction of stator units, anchored to the peptidoglycan cell wall, with the rotor. Recent…

Subcellular Processes · Quantitative Biology 2010-08-18 G. Meacci , Y. Tu

We present a simplified theory for semiflexible flagella under the action of a traveling-wave perturbation that emulates the organized active forces generated by molecular motors, capable of inducing beating patterns to the filament. By…

Soft Condensed Matter · Physics 2025-07-16 Fabio Cecconi , Dario Lucente , Andrea Puglisi , Massimiliano Viale

Suspensions of motile microorganisms can spontaneously form large-scale fluid motion, known as bioconvection, characterized by dense downwelling plumes separated by broad upwelling regions. In this study, we investigate bioconvection in…

Fluid Dynamics · Physics 2025-07-01 S. Gore , I. Gholami , S. O. Ahmed , T. Doskhozhina , S. V. R. Ambadipudi , A. J. Bae , A. Gholami

Axonemal dyneins are the molecular motors responsible for the beating of cilia and flagella. These motors generate sliding forces between adjacent microtubule doublets within the axoneme, the motile cytoskeletal structure inside the…

Biological Physics · Physics 2015-11-16 Pablo Sartori , Veikko Geyer , Andre Scholich , Frank Jülicher , Jonathon Howard

We analyze a one-dimensional two-scalar fields reaction advection diffusion model for the globally subcritical transition to turbulence. In this model, the homogeneous turbulent state is disconnected from the laminar one and disappears in a…

Fluid Dynamics · Physics 2024-07-09 Pavan V. Kashyap , Juan F. Marìn , Yohann Duguet , Olivier Dauchot

The stochastic dynamics of flagellar beating for micro-swimmers, such as flagellated cells, sperms and microalgae, is widely thought to include a feedback mechanism between flagellar shape and the rate of activation/de-activation of the $N…

Soft Condensed Matter · Physics 2026-05-01 F. Fanelli , A. Puglisi

Diffusion within porous media, such as biological tissues, exhibits departures from conventional Fick's laws, which could result in space-fractional diffusion. The paper considers a reaction-diffusion system with two spatial compartments --…

General Mathematics · Mathematics 2025-11-12 Dimiter Prodanov