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Ultrasound imaging of the cortex of long bones may enable the measurement of the cortical thickness and the ultrasound wave speed in cortical bone tissue. However, with bone loss, the cortical porosity and the size of the pores increase,…
Lung cancer is the most common form of cancer found worldwide with a high mortality rate. Early detection of pulmonary nodules by screening with a low-dose computed tomography (CT) scan is crucial for its effective clinical management.…
Automatic lymph node (LN) segmentation and detection for cancer staging are critical. In clinical practice, computed tomography (CT) and positron emission tomography (PET) imaging detect abnormal LNs. Despite its low contrast and variety in…
One of the fundamental requirements for an artificial hand to successfully grasp and manipulate an object is to be able to distinguish different objects' shapes and, more specifically, the objects' surface curvatures. In this study, we…
Wavefront sensing and reconstruction are widely used for adaptive optics, aberration correction, and high-resolution optical phase imaging. Traditionally, interference and/or microlens arrays are used to convert the optical phase into…
The response of adult human bone marrow stromal stem cells to surface topographies generated through femtosecond laser machining can be predicted by a deep neural network. The network is capable of predicting cell response to a…
Optical metasurfaces have been recently explored as ultrathin analog image differentiators. By tailoring the momentum transfer function, they can perform efficient Fourier-filtering - and thus potentially any linear mathematical operation -…
Understanding the structure of Earth's polar ice sheets is important for modeling how global warming will impact polar ice and, in turn, the Earth's climate. Ground-penetrating radar is able to collect observations of the internal structure…
Optical coherence tomography (OCT) is a non-invasive 3D modality widely used in ophthalmology for imaging the retina. Achieving automated, anatomically coherent retinal layer segmentation on OCT is important for the detection and monitoring…
A polarised light imaging microscopy with an addition of liquid crystal (LC) phase retarder was implemented to determine the birefringence of silk fibers with the high 2 micrometers spatial resolution. The measurement was carried out with…
A device capable of performing real time classification of proteins in a clinical setting would allow for inexpensive and rapid disease diagnosis. One such candidate for this technology are nanopore devices. These devices work by measuring…
The purpose of this paper is to help the anesthesiologist to find the epidural depth automatically to make the first attempt to enter the path of the needle into the patient's body while it is clogged with bone and avoid causing a puncture…
Significance: Cervical cancer progresses through cervical intraepithelial neoplasia (CIN), which are precursor lesions of cervical cancer. In low-grade CIN, atypical cells generate inside the squamous epithelium, which causes the accuracy…
We report experimentally and in theory on the detection of edge information in digital images using ultrafast spiking optical artificial neurons towards convolutional neural networks (CNNs). In tandem with traditional convolution…
Phase and polarisation of coherent light are highly perturbed by interaction with microstructural changes in pre-malignant tissue, holding promise for label-free early cancer detection in endoscopically accessible tissues such as the…
Spiders use their webs as multifunctional tools that enable capturing and localizing prey and more general environmental sensing through vibrations. Inspired by their biological function, we present a spider web-inspired optical waveguide…
We have extended Laser Doppler holographic microscopy to transmission geometry. The technique is validated with living fish embryos imaged by a modified upright bio-microcope. By varying the frequency of the holographic reference beam, and…
Optical coherence tomography (OCT) is commonly used to analyze retinal layers for assessment of ocular diseases. In this paper, we propose a method for retinal layer segmentation and quantification of uncertainty based on Bayesian deep…
Daily monitoring of internal tissues with conformable and breathable ultrasound (US) imaging probes is promising for early detection of diseases. In recent years, textile substrates are widely used for wearable devices since they satisfy…
Highly sensitive and selective label free devices for real-time identification of specific biomarkers are expected to significantly impact the biosensing field. The ability of plasmonic systems to confine the light in nanometer volume and…