Related papers: Needle guidance with Doppler-tracked polarization-…
Deep learning is able to functionally simulate the human brain and thus, it has attracted considerable interest. Optics-assisted deep learning is a promising approach to improve the forward-propagation speed and reduce the power…
We propose a method to monitor the progress of laser processing using laser speckle patterns. Laser grooving and percussion drilling were performed using femtosecond laser pulses. The speckle patterns from a processing point were monitored…
Nerve segmentation is crucial in medical imaging for precise identification of nerve structures. This study presents an optimized DeepLabV3-based segmentation pipeline that incorporates automated threshold fine-tuning to improve…
Purpose: To develop a deep learning approach to digitally-stain optical coherence tomography (OCT) images of the optic nerve head (ONH). Methods: A horizontal B-scan was acquired through the center of the ONH using OCT (Spectralis) for 1…
The polarization of light conveys crucial information about the spatial ordering and optical properties of a specimen. However, precise polarization measurement in challenging conditions, including constrained spaces, low light levels, and…
High-resolution optical imaging methods, such as confocal microscopy and full-field optical coherence tomography, capture flat optical sections of the sample. If the sample is curved, the optical field sections through several sample layers…
Currently, free flaps and pedicled flaps are assessed for reperfusion in post-operative care using colour, capillary refill, temperature, texture and Doppler signal (if available). While these techniques are effective, they are prone to…
We report an in-silico demonstration of an all-optical cell classification system using a single-layer diffractive neural network (DNN) optimized for real-world biomedical images. Implemented virtually with a spatial light modulator (SLM),…
Live cell imaging using metallic nanoparticles as tags is an emerging technique to visualize long and highly dynamic processes due to the lack of photobleaching and high photon rate. However, the lack of excited states as compared to…
Laser Doppler holography (LDH) is a full-field blood flow imaging technique able to reveal human retinal and choroidal blood flow with high temporal resolution. We here report on using LDH in the anterior segment of the eye without making…
The use of needles to access sites within organs is fundamental to many interventional medical procedures both for diagnosis and treatment. Safe and accurate navigation of a needle through living tissue to an intra-tissue target is…
Early detection and segmentation of skin lesions is crucial for timely diagnosis and treatment, necessary to improve the survival rate of patients. However, manual delineation is time consuming and subject to intra- and inter-observer…
We propose a general strategy for autonomous guidance and insertion of a needle into a retinal blood vessel. The main challenges underpinning this task are the accurate placement of the needle-tip on the target vein and a careful needle…
In this study, we investigate what a practically useful approach is in order to achieve robust skin disease diagnosis. A direct approach is to target the ground truth diagnosis labels, while an alternative approach instead focuses on…
Chiral molecule sensing is currently performed using chromatography, electrophoresis, enzymatic-assays, mass spectrometry, and chiroptical sensing techniques. Currently polarimetry is the only method having in-vivo sensing capabilities,…
We propose an enantioselective scheme to sort homogeneous chiral particles using optical tweezers. For a certain range of material parameters, we show that a highly focused circularly-polarized laser beam traps particles of a specific…
Measuring the field of visible light with high spatial resolution has been challenging, as many established methods only detect a focus-averaged signal. Here, we introduce a near-field method for optical field sampling that overcomes that…
Implantable silicon neural probes with integrated nanophotonic waveguides can deliver patterned dynamic illumination into brain tissue at depth. Here, we introduce neural probes with integrated optical phased arrays and demonstrate optical…
Medical image segmentation is the technique that helps doctor view and has a precise diagnosis, particularly in Colorectal Cancer. Specifically, with the increase in cases, the diagnosis and identification need to be faster and more…
Optical nanofiber waveguides are widely used for near-field delivery and measurement of light. Despite their versatility and efficiency, nanofibers have a critical drawback - their inability to maintain light's polarization state on…