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Background: Rapid advancements in natural language processing have led to the development of large language models with the potential to revolutionize mental health care. These models have shown promise in assisting clinicians and providing…

Computation and Language · Computer Science 2024-05-16 Birger Moell

Large language models (LLMs) have demonstrated remarkable capabilities in natural language understanding and generation across various domains, including medicine. We present a comprehensive evaluation of GPT-4, a state-of-the-art LLM, on…

Computation and Language · Computer Science 2023-04-13 Harsha Nori , Nicholas King , Scott Mayer McKinney , Dean Carignan , Eric Horvitz

Passively collected behavioral health data from ubiquitous sensors holds significant promise to provide mental health professionals insights from patient's daily lives; however, developing analysis tools to use this data in clinical…

Despite growing interest in using large language models (LLMs) in healthcare, current explorations do not assess the real-world utility and safety of LLMs in clinical settings. Our objective was to determine whether two LLMs can serve…

Large Language Models (LLMs) have demonstrated substantial progress in biomedical and clinical applications, motivating rigorous evaluation of their ability to answer nuanced, evidence-based questions. We curate a multi-source benchmark…

Computation and Language · Computer Science 2025-09-16 Can Wang , Yiqun Chen

Large Language Models (LLMs) have emerged as influential instruments within the realm of natural language processing; nevertheless, their capacity to handle multi-party conversations (MPCs) -- a scenario marked by the presence of multiple…

Computation and Language · Computer Science 2023-10-26 Chao-Hong Tan , Jia-Chen Gu , Zhen-Hua Ling

Large language models (LLMs), such as GPT-4, PaLM, and LLaMa, have been shown to achieve remarkable performance across a variety of natural language tasks. Recent advancements in instruction tuning bring LLMs with ability in following…

Computation and Language · Computer Science 2023-09-12 Vu-Thuan Doan , Quoc-Truong Truong , Duc-Vu Nguyen , Vinh-Tiep Nguyen , Thuy-Ngan Nguyen Luu

Evidence to guide healthcare decisions is often limited by a lack of relevant and trustworthy literature as well as difficulty in contextualizing existing research for a specific patient. Large language models (LLMs) could potentially…

Pre-trained language models (LLMs) such as GPT-3 can carry fluent, multi-turn conversations out-of-the-box, making them attractive materials for chatbot design. Further, designers can improve LLM chatbot utterances by prepending textual…

Human-Computer Interaction · Computer Science 2023-02-08 J. D. Zamfirescu-Pereira , Bjoern Hartmann , Qian Yang

Recent advances in large language models (LLMs) have shown impressive ability in biomedical question-answering, but have not been adequately investigated for more specific biomedical applications. This study investigates the performance of…

Computation and Language · Computer Science 2024-03-29 Shan Chen , Yingya Li , Sheng Lu , Hoang Van , Hugo JWL Aerts , Guergana K. Savova , Danielle S. Bitterman

Recent large language models (LLMs) offer the potential to support public health monitoring by facilitating health disclosure through open-ended conversations but rarely preserve the knowledge gained about individuals across repeated…

Human-Computer Interaction · Computer Science 2024-02-20 Eunkyung Jo , Yuin Jeong , SoHyun Park , Daniel A. Epstein , Young-Ho Kim

This article presents a comparative analysis of the ability of two large language model (LLM)-based chatbots, ChatGPT and Bing Chat, recently rebranded to Microsoft Copilot, to detect veracity of political information. We use AI auditing…

Computation and Language · Computer Science 2023-12-21 Elizaveta Kuznetsova , Mykola Makhortykh , Victoria Vziatysheva , Martha Stolze , Ani Baghumyan , Aleksandra Urman

Objective: Traditional phone-based surveys are among the most accessible and widely used methods to collect biomedical and healthcare data, however, they are often costly, labor intensive, and difficult to scale effectively. To overcome…

Computation and Language · Computer Science 2025-04-07 Kurmanbek Kaiyrbekov , Nicholas J Dobbins , Sean D Mooney

This paper describes a rapid feasibility study of using GPT-4, a large language model (LLM), to (semi)automate data extraction in systematic reviews. Despite the recent surge of interest in LLMs there is still a lack of understanding of how…

Computation and Language · Computer Science 2025-02-14 Lena Schmidt , Kaitlyn Hair , Sergio Graziosi , Fiona Campbell , Claudia Kapp , Alireza Khanteymoori , Dawn Craig , Mark Engelbert , James Thomas

By evaluating Large Language Models (LLMs) through uniform, text-only interfaces, current academic benchmarks obscure how the unique designs and affordances of distinct commercial platforms shape real-world user behavior and system…

Computation and Language · Computer Science 2026-05-19 Yueru Yan , Tuc Nguyen , Bo Su , Melissa Lieffers , Thai Le

Large language models (LLMs) chatbots like ChatGPT are increasingly used for mental health support. They offer accessible, therapeutic support but also raise concerns about misinformation, over-reliance, and risks in high-stakes contexts of…

Computers and Society · Computer Science 2025-12-09 Lingyao Li , Xiaoshan Huang , Renkai Ma , Ben Zefeng Zhang , Haolun Wu , Fan Yang , Chen Chen

$\textbf{Objectives}$: Large Language Models (LLMs) such as ChatGPT and Med-PaLM have excelled in various medical question-answering tasks. However, these English-centric models encounter challenges in non-English clinical settings,…

Computation and Language · Computer Science 2024-01-31 Jiageng Wu , Xian Wu , Zhaopeng Qiu , Minghui Li , Yingying Zhang , Yefeng Zheng , Changzheng Yuan , Jie Yang

Introduction. Advances in large language models (LLMs) offer a chance to act as scientific assistants, helping people grasp complex research areas. This study examines how LLMs evolve in healthcare disparities research, with attention to…

Computers and Society · Computer Science 2025-12-10 David An

The recent success of large language models (LLMs) has paved the way for their adoption in the high-stakes domain of healthcare. Specifically, the application of LLMs in patient-trial matching, which involves assessing patient eligibility…

Artificial Intelligence · Computer Science 2023-12-18 Mauro Nievas , Aditya Basu , Yanshan Wang , Hrituraj Singh

Background: Large Language Models (LLMs) are transforming artificial intelligence applications in healthcare due to their ability to understand, generate, and summarize complex medical text. They offer valuable support to clinicians,…

Computation and Language · Computer Science 2026-04-14 Subin Santhosh , Farwa Abbas , Hussain Ahmad , Claudia Szabo