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Pathological anomalies exhibit diverse appearances in medical imaging, making it difficult to collect and annotate a representative amount of data required to train deep learning models in a supervised setting. Therefore, in this work, we…

Image and Video Processing · Electrical Eng. & Systems 2023-07-18 Mariana-Iuliana Georgescu

With the development of medical imaging technology, medical images have become an important basis for doctors to diagnose patients. The brain structure in the collected data is complicated, thence, doctors are required to spend plentiful…

Image and Video Processing · Electrical Eng. & Systems 2020-07-10 Nan Wang , Chengwei Chen , Yuan Xie , Lizhuang Ma

Cancer is one of the deadliest diseases worldwide. Accurate diagnosis and classification of cancer subtypes are indispensable for effective clinical treatment. Promising results on automatic cancer subtyping systems have been published…

Machine Learning · Computer Science 2022-04-06 Ziwei Yang , Lingwei Zhu , Zheng Chen , Ming Huang , Naoaki Ono , MD Altaf-Ul-Amin , Shigehiko Kanaya

Unsupervised anomaly detection in brain images is crucial for identifying injuries and pathologies without access to labels. However, the accurate localization of anomalies in medical images remains challenging due to the inherent…

Computer Vision and Pattern Recognition · Computer Science 2025-07-25 Farzad Beizaee , Gregory Lodygensky , Christian Desrosiers , Jose Dolz

Anomaly detection for Magnetic Resonance Images (MRIs) can be solved with unsupervised methods by learning the distribution of healthy images and identifying anomalies as outliers. In presence of an additional dataset of unlabelled data…

Machine Learning · Computer Science 2020-07-27 Alexandra-Ioana Albu , Alina Enescu , Luigi Malagò

Accurate diagnosis of breast cancer in histopathology images is challenging due to the heterogeneity of cancer cell growth as well as of a variety of benign breast tissue proliferative lesions. In this paper, we propose a practical and…

Computer Vision and Pattern Recognition · Computer Science 2020-05-06 Xingyu Li , Marko Radulovic , Ksenija Kanjer , Konstantinos N. Plataniotis

Lesion detection in brain Magnetic Resonance Images (MRIs) remains a challenging task. MRIs are typically read and interpreted by domain experts, which is a tedious and time-consuming process. Recently, unsupervised anomaly detection (UAD)…

Image and Video Processing · Electrical Eng. & Systems 2022-02-01 Marcel Bengs , Finn Behrendt , Max-Heinrich Laves , Julia Krüger , Roland Opfer , Alexander Schlaefer

Anomaly detection (AD), separating anomalies from normal data, has many applications across domains, from security to healthcare. While most previous works were shown to be effective for cases with fully or partially labeled data, that…

Machine Learning · Computer Science 2022-08-08 Jinsung Yoon , Kihyuk Sohn , Chun-Liang Li , Sercan O. Arik , Chen-Yu Lee , Tomas Pfister

The increasing digitization of medical imaging enables machine learning based improvements in detecting, visualizing and segmenting lesions, easing the workload for medical experts. However, supervised machine learning requires reliable…

Image and Video Processing · Electrical Eng. & Systems 2024-12-03 Maximilian E. Tschuchnig , Michael Gadermayr

Self-supervised learning methods have witnessed a recent surge of interest after proving successful in multiple application fields. In this work, we leverage these techniques, and we propose 3D versions for five different self-supervised…

Computer Vision and Pattern Recognition · Computer Science 2020-11-03 Aiham Taleb , Winfried Loetzsch , Noel Danz , Julius Severin , Thomas Gaertner , Benjamin Bergner , Christoph Lippert

Unsupervised anomaly detection (UAD) seeks to localize the anomaly mask of an input image with respect to normal samples. Either by reconstructing normal counterparts (reconstruction-based) or by learning an image feature embedding space…

Image and Video Processing · Electrical Eng. & Systems 2025-10-06 Zhe Zhang , Mingxiu Cai , Hanxiao Wang , Gaochang Wu , Tianyou Chai , Xiatian Zhu

Confounding pathology with normal anatomical variation remains a significant challenge in unsupervised medical-image anomaly detection, resulting in numerous false positives. To enhance integration of healthy variation, we augment the…

Quantitative Methods · Quantitative Biology 2026-03-09 P. Bilha Githinji , Xi Yuan , Ijaz Gul , Lian Zhang , Jinhao Xu , Zhenglin Chen , Peiwu Qin , Dongmei Yu

It has recently been shown that deep learning models for anatomical segmentation in medical images can exhibit biases against certain sub-populations defined in terms of protected attributes like sex or ethnicity. In this context, auditing…

Computer Vision and Pattern Recognition · Computer Science 2023-09-04 Nicolás Gaggion , Rodrigo Echeveste , Lucas Mansilla , Diego H. Milone , Enzo Ferrante

Anomaly detection in visual data refers to the problem of differentiating abnormal appearances from normal cases. Supervised approaches have been successfully applied to different domains, but require an abundance of labeled data. Due to…

Image and Video Processing · Electrical Eng. & Systems 2021-04-29 Dejan Stepec , Danijel Skocaj

Diffusion magnetic resonance imaging (dMRI) is a crucial technique in neuroimaging studies, allowing for the non-invasive probing of the underlying structures of brain tissues. Clinical dMRI data is susceptible to various artifacts during…

Image and Video Processing · Electrical Eng. & Systems 2024-09-25 Sheng Chen , Zihao Tang , Xinyi Wang , Chenyu Wang , Weidong Cai

We present a machine learning method capable of accurately detecting chromosome abnormalities that cause blood cancers directly from microscope images of the metaphase stage of cell division. The pipeline is built on a series of fine-tuned…

Collecting pixel-level labels for medical datasets can be a laborious and expensive process, and enhancing segmentation performance with a scarcity of labeled data is a crucial challenge. This work introduces AugPaint, a data augmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Xinrong Hu , Yiyu Shi

Universal anomaly detection still remains a challenging problem in machine learning and medical image analysis. It is possible to learn an expected distribution from a single class of normative samples, e.g., through epistemic uncertainty…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 Johanna P. Müller , Matthew Baugh , Jeremy Tan , Mischa Dombrowski , Bernhard Kainz

Ultrasound imaging is challenging to interpret due to non-uniform intensities, low contrast, and inherent artifacts, necessitating extensive training for non-specialists. Advanced representation with clear tissue structure separation could…

Computer Vision and Pattern Recognition · Computer Science 2024-08-06 Oleksandra Tmenova , Yordanka Velikova , Mahdi Saleh , Nassir Navab

In real-world clinical practice, overlooking unanticipated findings can result in serious consequences. However, supervised learning, which is the foundation for the current success of deep learning, only encourages models to identify…