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In safety-critical applications like medical diagnosis, certainty associated with a model's prediction is just as important as its accuracy. Consequently, uncertainty estimation and reduction play a crucial role. Uncertainty in predictions…

Image and Video Processing · Electrical Eng. & Systems 2023-09-12 Abhishek Singh Sambyal , Narayanan C. Krishnan , Deepti R. Bathula

In the cancer diagnosis pipeline, digital pathology plays an instrumental role in the identification, staging, and grading of malignant areas on biopsy tissue specimens. High resolution histology images are subject to high variance in…

Image and Video Processing · Electrical Eng. & Systems 2023-08-17 Vasileios Magoulianitis , Catherine A. Alexander , C. -C. Jay Kuo

Self-supervised learning has proven to be invaluable in making best use of all of the available data in biomedical image segmentation. One particularly simple and effective mechanism to achieve self-supervision is inpainting, the task of…

Computer Vision and Pattern Recognition · Computer Science 2023-07-06 Subhradeep Kayal , Shuai Chen , Marleen de Bruijne

The core challenge in unsupervised anomaly detection is identifying abnormal patterns without prior knowledge of their characteristics. While existing methods have addressed aspects of this problem, they often struggle to learn a robust…

Machine Learning · Computer Science 2026-05-12 Prithul Sarker , Sushmita Sarker , Nicholas G. Murray , Alireza Tavakkoli

Deep learning based approaches to Computer Aided Diagnosis (CAD) typically pose the problem as an image classification (Normal or Abnormal) problem. These systems achieve high to very high accuracy in specific disease detection for which…

Computer Vision and Pattern Recognition · Computer Science 2020-10-06 Aniket Joshi , Gaurav Mishra , Jayanthi Sivaswamy

Automatic skin lesion segmentation on dermoscopic images is an essential component in computer-aided diagnosis of melanoma. Recently, many fully supervised deep learning based methods have been proposed for automatic skin lesion…

Computer Vision and Pattern Recognition · Computer Science 2018-08-14 Xiaomeng Li , Lequan Yu , Hao Chen , Chi-Wing Fu , Pheng-Ann Heng

Anomaly detection (AD) is a crucial task in machine learning with various applications, such as detecting emerging diseases, identifying financial frauds, and detecting fake news. However, obtaining complete, accurate, and precise labels…

Machine Learning · Computer Science 2023-02-10 Minqi Jiang , Chaochuan Hou , Ao Zheng , Xiyang Hu , Songqiao Han , Hailiang Huang , Xiangnan He , Philip S. Yu , Yue Zhao

In the advancement of industrial informatization, unsupervised anomaly detection technology effectively overcomes the scarcity of abnormal samples and significantly enhances the automation and reliability of smart manufacturing. As an…

Computer Vision and Pattern Recognition · Computer Science 2025-03-24 Yuxuan Lin , Yang Chang , Xuan Tong , Jiawen Yu , Antonio Liotta , Guofan Huang , Wei Song , Deyu Zeng , Zongze Wu , Yan Wang , Wenqiang Zhang

Unsupervised anomaly detection is a popular approach for the analysis of neuroimaging data as it allows to identify a wide variety of anomalies from unlabelled data. It relies on building a subject-specific model of healthy appearance to…

Image and Video Processing · Electrical Eng. & Systems 2023-11-22 Maëlys Solal , Ravi Hassanaly , Ninon Burgos

Continuous efforts are being made to advance anomaly detection in various manufacturing processes to increase the productivity and safety of industrial sites. Deep learning replaced rule-based methods and recently emerged as a promising…

Machine Learning · Computer Science 2024-06-28 Kukjin Choi , Jihun Yi , Jisoo Mok , Sungroh Yoon

Anomaly detection in medical imaging plays a crucial role in identifying pathological regions across various imaging modalities, such as brain MRI, liver CT, and carotid ultrasound (US). However, training fully supervised segmentation…

Image and Video Processing · Electrical Eng. & Systems 2025-07-29 Yuan Bi , Lucie Huang , Ricarda Clarenbach , Reza Ghotbi , Angelos Karlas , Nassir Navab , Zhongliang Jiang

Brain pathologies can vary greatly in size and shape, ranging from few pixels (i.e. MS lesions) to large, space-occupying tumors. Recently proposed Autoencoder-based methods for unsupervised anomaly segmentation in brain MRI have shown…

Image and Video Processing · Electrical Eng. & Systems 2020-06-24 Christoph Baur , Benedikt Wiestler , Shadi Albarqouni , Nassir Navab

Robust segmentation is critical for deriving quantitative measures from large-scale, multi-center, and longitudinal medical scans. Manually annotating medical scans, however, is expensive and labor-intensive and may not always be available…

In order to support the creation of reliable machine learning models for anomaly detection, this project focuses on preprocessing, enhancing, and organizing a medical imaging dataset. There are two classifications in the dataset: normal and…

Image and Video Processing · Electrical Eng. & Systems 2024-11-20 Dharanidharan S , Suhitha Renuka S , Ajishi Singh , Sheena Christabel Pravin

Unsupervised anomaly detection (AD) in medical images aims to identify abnormal regions without relying on pixel-level annotations, which is crucial for scalable and label-efficient diagnostic systems. In this paper, we propose a novel…

Image and Video Processing · Electrical Eng. & Systems 2026-02-05 Jiayu Huo , Jingyuan Hong , Liyun Chen

Angiogenesis, the formation of new vessels, is one of the key mechanisms in tumor development and an appealing target for therapy. Non-invasive, high-resolution, high sensitivity, quantitative 3D imaging techniques are required to correctly…

Image and Video Processing · Electrical Eng. & Systems 2019-12-06 Charlie Demené , Thomas Payen , Alexandre Dizeux , Guillaume Barrois , Jean-Luc Gennisson , Lori Bridal , Mickael Tanter

Relatively abundant availability of medical imaging data has provided significant support in the development and testing of Neural Network based image processing methods. Clinicians often face issues in selecting suitable image processing…

Image and Video Processing · Electrical Eng. & Systems 2021-09-10 Mayank Goswami

The automated detection of cancerous tumors has attracted interest mainly during the last decade, due to the necessity of early and efficient diagnosis that will lead to the most effective possible treatment of the impending risk. Several…

Image and Video Processing · Electrical Eng. & Systems 2023-10-13 Vasileios E. Papageorgiou , Pantelis Dogoulis , Dimitrios-Panagiotis Papageorgiou

4D CT imaging is an essential component of radiotherapy of thoracic/abdominal tumors. 4D CT images are, however, often affected by artifacts that compromise treatment planning quality. In this work, deep learning (DL)-based conditional…

Medical Physics · Physics 2024-11-26 Frederic Madesta , Thilo Sentker , Tobias Gauer , Rene Werner

Anomaly detection in medical imaging is to distinguish the relevant biomarkers of diseases from those of normal tissues. Deep supervised learning methods have shown potentials in various detection tasks, but its performances would be…

Image and Video Processing · Electrical Eng. & Systems 2021-12-01 Byungjai Kim , Kinam Kwon , Changheun Oh , Hyunwook Park
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