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Background: Multi-collimator proton minibeam radiation therapy (MC-pMBRT) has recently emerged as a versatile technique for dose shaping, enabling peak-valley dose patterns in organs-at-risk (OAR) while maintaining a uniform dose…

Medical Physics · Physics 2025-02-25 Nimita Shinde , Weijie Zhang , Yuting Lin , Hao Gao

As the artificial intelligence community advances into the era of large models with billions of parameters, distributed training and inference have become essential. While various parallelism strategies-data, model, sequence, and…

Machine Learning · Computer Science 2025-03-13 Ruifeng She , Bowen Pang , Kai Li , Zehua Liu , Tao Zhong

This paper addresses the problem of motion planning for differential drive micro-mobility platforms. This class of vehicle is designed to perform small-distance transportation of passengers and goods in structured environments. Our approach…

Robotics · Computer Science 2025-05-15 Angelo Caregnato-Neto , Janito Vaqueiro Ferreira

We address the joint optimization of multiple stream joins in a scale-out architecture by tailoring prior work on multi-way stream joins to predicate-driven data partitioning schemes. We present an integer linear programming (ILP)…

Databases · Computer Science 2021-04-19 Manuel Dossinger , Sebastian Michel

We propose an early termination technique for mixed integer conic programming for use within branch-and-bound based solvers. Our approach generalizes previous early termination results for ADMM-based solvers to a broader class of…

Optimization and Control · Mathematics 2023-03-17 Yuwen Chen , Catherine Ning , Paul Goulart

Offline preference optimization methods, such as Direct Preference Optimization (DPO), offer significant advantages in aligning Large Language Models (LLMs) with human values. However, achieving optimal performance with these methods…

Machine Learning · Computer Science 2026-04-29 Peng Liao , Peijia Zheng , Lingbo Li , Shangsong Liang , Lin Chen

We propose an ML-based model that automates and expedites the solution of MIPs by predicting the values of variables. Our approach is motivated by the observation that many problem instances share salient features and solution structures…

Optimization and Control · Mathematics 2023-02-24 Konstantinos Benidis , Ugo Rosolia , Syama Rangapuram , George Iosifidis , Georgios Paschos

In Mixed Integer Linear Programming (MIP), a (strong) backdoor is a "small" subset of an instance's integer variables with the following property: in a branch-and-bound procedure, the instance can be solved to global optimality by branching…

Artificial Intelligence · Computer Science 2022-07-11 Elias B. Khalil , Pashootan Vaezipoor , Bistra Dilkina

Large Language Models (LLMs) have enabled dynamic reasoning in automated data analytics, yet recent multi-agent systems remain limited by rigid, single-path workflows that restrict strategic exploration and often lead to suboptimal…

Artificial Intelligence · Computer Science 2026-01-08 Wonduk Seo , Juhyeon Lee , Yanjun Shao , Qingshan Zhou , Seunghyun Lee , Yi Bu

In this work, we consider multiobjective optimization problems with both bound constraints on the variables and general nonlinear constraints, where objective and constraint function values can only be obtained by querying a black box.…

Optimization and Control · Mathematics 2022-04-15 Giampaolo Liuzzi , Stefano Lucidi

In multi-user millimeter wave (mmWave) multiple-input-multiple-output (MIMO) systems, hybrid precoding is a crucial task to lower the complexity and cost while achieving a sufficient sum-rate. Previous works on hybrid precoding were usually…

Signal Processing · Electrical Eng. & Systems 2020-04-28 Ahmet M. Elbir , Anastasios Papazafeiropoulos

We consider the problem of learning optimal binary classification trees. Literature on the topic has burgeoned in recent years, motivated both by the empirical suboptimality of heuristic approaches and the tremendous improvements in…

Machine Learning · Statistics 2020-05-14 Sina Aghaei , Andres Gomez , Phebe Vayanos

Multilevel optimization has gained renewed interest in machine learning due to its promise in applications such as hyperparameter tuning and continual learning. However, existing methods struggle with the inherent difficulty of efficiently…

Machine Learning · Computer Science 2024-10-16 Yuntian Gu , Xuzheng Chen

Configuration integer programs (IP) have been key in the design of algorithms for NP-hard high-multiplicity problems since the pioneering work of Gilmore and Gomory [Oper. Res., 1961]. Configuration IPs have a variable for each possible…

Data Structures and Algorithms · Computer Science 2019-09-17 Dušan Knop , Martin Koutecký , Asaf Levin , Matthias Mnich , Shmuel Onn

Primal heuristics play a crucial role in exact solvers for Mixed Integer Programming (MIP). While solvers are guaranteed to find optimal solutions given sufficient time, real-world applications typically require finding good solutions early…

Machine Learning · Computer Science 2021-03-19 Antonia Chmiela , Elias B. Khalil , Ambros Gleixner , Andrea Lodi , Sebastian Pokutta

We propose a novel solution framework for inverse mixed-integer optimization based on analytic center concepts from interior point methods. We characterize the optimality gap of a given solution, provide structural results, and propose…

Optimization and Control · Mathematics 2025-04-08 Samir Elhedhli , Göksu Ece Okur

Grid layouts are used by designers to spatially organise user interfaces when sketching and wireframing. However, their design is largely time consuming manual work. This is challenging due to combinatorial explosion and complex objectives,…

Human-Computer Interaction · Computer Science 2020-01-10 Niraj Dayama , Kashyap Todi , Taru Saarelainen , Antti Oulasvirta

Finding a high-quality feasible solution to a combinatorial optimization (CO) problem in a limited time is challenging due to its discrete nature. Recently, there has been an increasing number of machine learning (ML) methods for addressing…

Optimization and Control · Mathematics 2023-08-02 Taehyun Yoon , Jinwon Choi , Hyokun Yun , Sungbin Lim

Offline preference alignment for language models such as Direct Preference Optimization (DPO) is favored for its effectiveness and simplicity, eliminating the need for costly reinforcement learning. Various offline algorithms have been…

Machine Learning · Computer Science 2025-07-28 Junbo Li , Zhangyang Wang , Qiang Liu

Mixed-integer model predictive control (MI-MPC) can be a powerful tool for modeling hybrid control systems. In case of a linear-quadratic objective in combination with linear or piecewise-linear system dynamics and inequality constraints,…

Optimization and Control · Mathematics 2023-07-12 Rien Quirynen , Stefano Di Cairano