English
Related papers

Related papers: AutoTrial: Prompting Language Models for Clinical …

200 papers

We develop a method for assigning high-quality labels to unstructured text. This method is based on fine-tuning an efficient, open-source language model with data extracted from a large, proprietary language model. We apply this method to…

General Economics · Economics 2025-01-27 Maya M. Durvasula , Sabri Eyuboglu , David M. Ritzwoller

Fine-tuning vision-language models (VLMs) with abundant unlabeled data recently has attracted increasing attention. Existing methods that resort to the pseudolabeling strategy would suffer from heavily incorrect hard pseudolabels when VLMs…

Machine Learning · Computer Science 2024-06-18 Jiahan Zhang , Qi Wei , Feng Liu , Lei Feng

Test cases are essential for validating the reliability and quality of software applications. Recent studies have demonstrated the capability of Large Language Models (LLMs) to generate useful test cases for given source code. However, the…

Software Engineering · Computer Science 2025-01-03 Shuzheng Gao , Chaozheng Wang , Cuiyun Gao , Xiaoqian Jiao , Chun Yong Chong , Shan Gao , Michael Lyu

Conditional natural language generation methods often require either expensive fine-tuning or training a large language model from scratch. Both are unlikely to lead to good results without a substantial amount of data and computational…

Computation and Language · Computer Science 2023-08-10 Yarik Menchaca Resendiz , Roman Klinger

In research areas with scarce data, representation learning plays a significant role. This work aims to enhance representation learning for clinical time series by deriving universal embeddings for clinical features, such as heart rate and…

Machine Learning · Computer Science 2024-02-07 Yurong Hu , Manuel Burger , Gunnar Rätsch , Rita Kuznetsova

In recent years, Large Language Models (LLMs) have made significant strides towards Artificial General Intelligence. However, training these models from scratch requires substantial computational resources and vast amounts of text data. In…

Computation and Language · Computer Science 2024-10-03 Wenzhen Zheng , Wenbo Pan , Xu Xu , Libo Qin , Li Yue , Ming Zhou

A language model can be used to predict the next word during authoring, to correct spelling or to accelerate writing (e.g., in sms or emails). Language models, however, have only been applied in a very small scale to assist physicians…

Computation and Language · Computer Science 2020-06-23 John Pavlopoulos , Panagiotis Papapetrou

Diagnostic and prognostic models are increasingly important in medicine and inform many clinical decisions. Recently, machine learning approaches have shown improvement over conventional modeling techniques by better capturing complex…

Machine Learning · Computer Science 2024-03-01 Fergus Imrie , Bogdan Cebere , Eoin F. McKinney , Mihaela van der Schaar

Recent advancements in large language models (LLMs) on language modeling and emergent capabilities make them a promising reference-free evaluator of natural language generation quality, and a competent alternative to human evaluation.…

Computation and Language · Computer Science 2023-09-26 Yuxuan Liu , Tianchi Yang , Shaohan Huang , Zihan Zhang , Haizhen Huang , Furu Wei , Weiwei Deng , Feng Sun , Qi Zhang

Clinical practice guidelines (CPGs) encode evidence-based decision logic that clinicians apply by evaluating patient variables, conditional criteria, and recommendation rules. However, existing methods often use CPGs as free-text training…

Artificial Intelligence · Computer Science 2026-05-27 Yuhao Shen , Lang Cao , Simo Du , Yuqing Wang , Juexiao Zhou , Hao Peng , Yue Guo

The clinical trial process, a critical phase in drug development, is essential for developing new treatments. The primary goal of interventional clinical trials is to evaluate the safety and efficacy of drug-based treatments for specific…

Machine Learning · Computer Science 2024-07-19 Ling Yue , Jonathan Li , Sixue Xing , Md Zabirul Islam , Bolun Xia , Tianfan Fu , Jintai Chen

Guiding large language models with a selected set of human-authored demonstrations is a common practice for improving LLM applications. However, human effort can be costly, especially in specialized domains (e.g., clinical diagnosis), and…

Artificial Intelligence · Computer Science 2024-08-23 Kai Tzu-iunn Ong , Taeyoon Kwon , Jinyoung Yeo

Clinical note classification is a common clinical NLP task. However, annotated data-sets are scarse. Prompt-based learning has recently emerged as an effective method to adapt pre-trained models for text classification using only few…

Computation and Language · Computer Science 2023-11-01 Eugenia Alleva , Isotta Landi , Leslee J Shaw , Erwin Böttinger , Thomas J Fuchs , Ipek Ensari

Clinical language models have achieved strong performance on downstream tasks by pretraining on domain specific corpora such as discharge summaries and medical notes. However, most approaches treat the electronic health record as a static…

Computation and Language · Computer Science 2025-04-28 Tatsunori Tanaka , Fi Zheng , Kai Sato , Zhifeng Li , Yuanyun Zhang , Shi Li

Clinical trial amendments frequently introduce delays, increased costs, and administrative burden, with eligibility criteria being the most commonly amended component. We introduce \textit{eligibility criteria amendment prediction}, a novel…

Computation and Language · Computer Science 2026-01-13 Trisha Das , Mandis Beigi , Jacob Aptekar , Jimeng Sun

The clinical adoption of biomedical vision-language models is hindered by prompt optimization techniques that produce either uninterpretable latent vectors or single textual prompts. This lack of transparency and failure to capture the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-20 Kaushitha Silva , Mansitha Eashwara , Sanduni Ubayasiri , Ruwan Tennakoon , Damayanthi Herath

This work presents an analytical framework for the design and analysis of LLM-based algorithms, i.e., algorithms that contain one or multiple calls of large language models (LLMs) as sub-routines and critically rely on the capabilities of…

Machine Learning · Computer Science 2025-10-14 Yanxi Chen , Yaliang Li , Bolin Ding , Jingren Zhou

The clinical trial is a pivotal and costly process, often spanning multiple years and requiring substantial financial resources. Therefore, the development of clinical trial outcome prediction models aims to exclude drugs likely to fail and…

Machine Learning · Computer Science 2025-01-29 Wenhao Zheng , Liaoyaqi Wang , Dongshen Peng , Hongxia Xu , Yun Li , Hongtu Zhu , Tianfan Fu , Huaxiu Yao

The increasing availability of unstructured clinical narratives in electronic health records (EHRs) has created new opportunities for automated disease characterization, cohort identification, and clinical decision support. However,…

Computation and Language · Computer Science 2026-03-03 Fariba Afrin Irany , Sampson Akwafuo

In computer science, students are encouraged to learn various programming languages such as Python, C++, and Java, equipping them with a broad range of technical skills and problem-solving capabilities. Nevertheless, the design of objective…

Programming Languages · Computer Science 2026-03-17 Jongwook Si , Sungyoung Kim