Related papers: Self-Supervised Learning for Physiologically-Based…
Facial feature tracking is essential in imaging ballistocardiography for accurate heart rate estimation and enables motor degradation quantification in Parkinson's disease through skin feature tracking. While deep convolutional neural…
Parameter-efficient tuning (PET) aims to transfer pre-trained foundation models to downstream tasks by learning a small number of parameters. Compared to traditional fine-tuning, which updates the entire model, PET significantly reduces…
Population pharmacokinetic (PopPK) modelling is a fundamental tool for understanding drug behaviour across diverse patient populations and enabling personalized dosing strategies to improve therapeutic outcomes. A key challenge in PopPK…
Longitudinal imaging is capable of capturing the static ana\-to\-mi\-cal structures and the dynamic changes of the morphology resulting from aging or disease progression. Self-supervised learning allows to learn new representation from…
The kernel reconstruction is a method that reduces noise in dynamic positron emission tomography (PET) by exploiting spatial correlations in the PET image. Although this method works well for large anatomical regions with relatively slow…
Low-dose positron emission tomography (PET) image reconstruction methods have potential to significantly improve PET as an imaging modality. Deep learning provides a promising means of incorporating prior information into the image…
[18F]FDG-PET/CT is a cornerstone imaging modality for tumor staging and treatment response assessment across many cancer types, yet expert reader shortages necessitate more efficient diagnostic aids. While standalone AI models for automatic…
Positron emission tomography (PET) is a widely used, highly sensitive molecular imaging in clinical diagnosis. There is interest in reducing the radiation exposure from PET but also maintaining adequate image quality. Recent methods using…
Positron Emission Tomography (PET) /Computed Tomography (CT) is crucial for diagnosing, managing, and planning treatment for various cancers. Developing reliable deep learning models for the segmentation of tumor lesions in PET/CT scans in…
Image reconstruction for positron emission tomography (PET) is challenging because of the ill-conditioned tomographic problem and low counting statistics. Kernel methods address this challenge by using kernel representation to incorporate…
Background and Objective. Research in the cross-modal medical image translation domain has been very productive over the past few years in tackling the scarce availability of large curated multimodality datasets with the promising…
Recent breakthroughs in self-supervised learning have enabled the use of large unlabeled datasets to train visual foundation models that can generalize to a variety of downstream tasks. While this training paradigm is well suited for the…
Uncertainty estimation is an important task for critical problems, such as robotics and autonomous driving, because it allows creating statistically better perception models and signaling the model's certainty in its predictions to the…
Physiologically Based Pharmacokinetic (PBPK) modeling is a cornerstone of model-informed drug development (MIDD), providing a mechanistic framework to predict drug absorption, distribution, metabolism, and excretion (ADME). Despite its…
Imaging in clinical oncology trials provides a wealth of information that contributes to the drug development process, especially in early phase studies. This paper focuses on kinetic modeling in DCE-MRI, inspired by mixed-effects models…
Automated segmentation of cancerous lesions in PET/CT scans is a crucial first step in quantitative image analysis. However, training deep learning models for segmentation with high accuracy is particularly challenging due to the variations…
The aim of this paper is to discuss potential advances in PET kinetic models and direct reconstruction of kinetic parameters. As a prominent example we focus on a typical task in perfusion imaging and derive a system of…
Subject motion in whole-body dynamic PET introduces inter-frame mismatch and seriously impacts parametric imaging. Traditional non-rigid registration methods are generally computationally intense and time-consuming. Deep learning approaches…
Pancreatic cancer with more than 60,000 new cases each year has less than 10 percent 5-year overall survival. Radiation therapy (RT) is an effective treatment for Locally advanced pancreatic cancer (LAPC). The current clinical RT workflow…
Cardiac 18F-FDG PET has been used in clinics to assess myocardial glucose metabolism. Its ability for imaging myocardial glucose transport, however, has rarely been exploited in clinics. Using the dynamic FDG-PET scans of ten patients with…