Related papers: Mathematical Analysis of Autonomous and Nonautonom…
Hepatitis B is a potentially life-threatening liver infection caused by the hepatitis B virus (HBV). In this paper, the transmission dynamics of hepatitis B is formulated with a mathematical model with considerations of different classes of…
The aims of this work is to analyse of the global stability of the extended model of hepatitis C virus(HCV) infection with cellular proliferation, spontaneous cure and hepatocyte homeostasis. We first give general information about…
In this paper, a mathematical analysis of the global dynamics of a partial differential equation viral infection cellular model is carried out. We study the dynamics of a hepatitis C virus (HCV) model, under therapy, that considers both…
This study develops and analyzes a stochastic differential equation (SDE) model for the dynamics of hepatitis B virus (HBV) infection. While deterministic frameworks have yielded important insights into viral behavior, they cannot…
We investigate the dynamics of the hepatitis B virus by integrating variable-order calculus and discrete analysis. Specifically, we utilize the Caputo variable-order difference operator in this study. To establish the existence and…
A new detailed mathematical model for dynamics of immune response to hepatitis B is proposed, which takes into account contributions from innate and adaptive immune responses, as well as cytokines. Stability analysis of different steady…
Hepatitis type B is one of the most common infectious disease worldwide that can pose severe threats to human health up to the point that may contribute to severe liver damage or cancer. Over the past two decades a large number of dynamic…
Analysis of the cell population generally provides average information about viral infection in a host whereas the intracellular model captures the individual cellular responses. The primary goal of this study is to comprehensively analyze…
In this paper, we present the global analysis of a HCV model under therapy. We prove that the solutions with positive initial values are global, positive, bounded and not display periodic orbits. In addition, we show that the model is…
We consider a mathematical model comprising of four coupled ordinary differential equations (ODEs) for studying the hepatitis C (HCV) viral dynamics. The model embodies the efficacies of a combination therapy of interferon and ribavirin. A…
In this work, a hepatitis B virus infection dynamics model is proposed including the spatial dependence of viruses. The existence of traveling waves for the proposed model is established through the application of the celebrated Gersgorin…
Chronic infection with hepatitis B virus (HBV) can lead to formation of abnormal nodular structures within the liver. To address how changes in liver anatomy affect overall virus-host dynamics, we developed within-host ordinary differential…
We consider a spatially-heterogeneous generalization of a well-established model for the dynamics of the Human Immunodeficiency Virus-type 1 (HIV) within a susceptible host. The model consists of a nonlinear system of three coupled…
A mathematical modeling of Hepatitis C Virus (HCV) dynamics has been presented in this paper. The proposed model, which involves four coupled ordinary differential equations, describes the interaction of target cells (hepatocytes), infected…
In this paper, a mathematical analysis of the global dynamics of a viral infection model in vivo is carried out. We study the dynamics of a hepatitis C virus (HCV) model, under therapy, that considers both extracellular and intracellular…
Hepatitis B virus (HBV) is considered as etiological agent of the lethal liver disease hepatitis B. Globally, hepatitis B is recognized as one of the prevailing infectious diseases with a significant impact on human health. In spite of…
This paper considers a mathematical model based on the transmission dynamics of hepatitis C virus (HCV) infection. In addition to the usual compartments for susceptible, exposed, and infected individuals, this model includes compartments…
Cost-effectiveness analyses, based on decision-analytic models of disease progression and treatment, are routinely used to assess the economic value of a new intervention and consequently inform reimbursement decisions for the intervention.…
In this paper we study a model of HCV with mitotic proliferation, a saturation infection rate and a discrete intracellular delay: the delay corresponds to the time between infection of a infected target hepatocytes and production of new HCV…
We study within-host HIV dynamics using a three--component nonlinear ordinary differential equation model for healthy CD4$^{+}$ T cells, infected CD4$^{+}$ T cells, and free virus. In addition to the baseline model without treatment, we…