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Preventable or undiagnosed visual impairment and blindness affect billion of people worldwide. Automated multi-disease detection models offer great potential to address this problem via clinical decision support in diagnosis. In this work,…

Image and Video Processing · Electrical Eng. & Systems 2021-03-30 Dominik Müller , Iñaki Soto-Rey , Frank Kramer

A variety of vision ailments are associated with geographic atrophy (GA) in the foveal region of the eye. In current clinical practice, the ophthalmologist manually detects potential presence of such GA based on fundus autofluorescence…

Our research is motivated by the urgent global issue of a large population affected by retinal diseases, which are evenly distributed but underserved by specialized medical expertise, particularly in non-urban areas. Our primary objective…

Computer Vision and Pattern Recognition · Computer Science 2025-03-28 Deependra Singh , Saksham Agarwal , Subhankar Mishra

Observing retinal fundus images by an ophthalmologist is a major diagnosis approach for glaucoma. However, it is still difficult to distinguish the features of the lesion solely through manual observations, especially, in glaucoma early…

Image and Video Processing · Electrical Eng. & Systems 2020-01-08 Peng Liu , Ruogu Fang

Central palsy is a form of facial paralysis that requires urgent medical attention and has to be differentiated from other, similar conditions such as peripheral palsy. To aid in fast and accurate diagnosis of this condition, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2022-01-31 C. V. Vletter , H. L. Burger , H. Alers , N. Sourlos , Z. Al-Ars

We propose a robust alignment technique for Standard Fundus Images (SFIs) and Ultra-Widefield Fundus Images (UWFIs), which are challenging to align due to differences in scale, appearance, and the scarcity of distinctive features. Our…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Kanggeon Lee , Soochahn Lee , Kyoung Mu Lee

Imaging methods by using computer techniques provide doctors assistance at any time and relieve their workload, especially for iterative processes like identifying objects of interest such as lesions and anatomical structures from the…

Medical Physics · Physics 2020-04-22 Meysam Tavakoli , Sina Jazani , Mahdieh Nazar

Diabetic retinopathy is one of the most threatening complications of diabetes that leads to permanent blindness if left untreated. One of the essential challenges is early detection, which is very important for treatment success.…

Machine Learning · Computer Science 2020-03-06 Borys Tymchenko , Philip Marchenko , Dmitry Spodarets

There exist numerous diagnostic tasks in pathology. Conventional computational pathology formulates and tackles them as independent and individual image classification problems, thereby resulting in computational inefficiency and high…

Image and Video Processing · Electrical Eng. & Systems 2024-07-15 Anh Tien Nguyen , Keunho Byeon , Kyungeun Kim , Boram Song , Seoung Wan Chae , Jin Tae Kwak

The emergence of vision-language models has transformed medical AI, enabling unprecedented advances in diagnostic capability and clinical applications. However, progress in dermatology has lagged behind other medical domains due to the lack…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Siyuan Yan , Ming Hu , Yiwen Jiang , Xieji Li , Hao Fei , Philipp Tschandl , Harald Kittler , Zongyuan Ge

The Segment Anything Model (SAM) has gained popularity as a versatile image segmentation method, thanks to its strong generalization capabilities across various domains. However, when applied to optic disc (OD) and optic cup (OC)…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Jinchen Yu , Yongwei Nie , Fei Qi , Wenxiong Liao , Hongmin Cai

Diabetic Retinopathy (DR) is a constantly deteriorating disease, being one of the leading causes of vision impairment and blindness. Subtle distinction among different grades and existence of many significant small features make the task of…

Computer Vision and Pattern Recognition · Computer Science 2018-12-31 Sheikh Muhammad Saiful Islam , Md Mahedi Hasan , Sohaib Abdullah

High myopia significantly increases the risk of irreversible vision loss. Traditional perimetry-based visual field (VF) assessment provides systematic quantification of visual loss but it is subjective and time-consuming. Consequently,…

Computer Vision and Pattern Recognition · Computer Science 2024-07-18 Zipei Yan , Zhile Liang , Zhengji Liu , Shuai Wang , Rachel Ka-Man Chun , Jizhou Li , Chea-su Kee , Dong Liang

Importance: Machine learning (ML) approaches to facial landmark localization carry great clinical potential for quantitative assessment of facial function as they enable high-throughput automated quantification of relevant facial metrics…

Computer Vision and Pattern Recognition · Computer Science 2020-03-19 Diego L. Guarin , Yana Yunusova , Babak Taati , Joseph R Dusseldorp , Suresh Mohan , Joana Tavares , Martinus M. van Veen , Emily Fortier , Tessa A. Hadlock , Nate Jowett

The joint interpretation of multi-modal and multi-view fundus images is critical for retinopathy prevention, as different views can show the complete 3D eyeball field and different modalities can provide complementary lesion areas. Compared…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Yonghao Huang , Leiting Chen , Chuan Zhou

Glaucoma is one of the leading causes of irreversible but preventable blindness in working age populations. Color fundus photography (CFP) is the most cost-effective imaging modality to screen for retinal disorders. However, its application…

Significant advancements in AI-driven multimodal medical image diagnosis have led to substantial improvements in ophthalmic disease identification in recent years. However, acquiring paired multimodal ophthalmic images remains prohibitively…

Computer Vision and Pattern Recognition · Computer Science 2025-09-11 Zhihao Zhao , Yinzheng Zhao , Junjie Yang , Xiangtong Yao , Quanmin Liang , Daniel Zapp , Kai Huang , Nassir Navab , M. Ali Nasseri

The visual analysis of retina and of its vascular characteristics is important in the diagnosis and monitoring of diseases of visual perception. In the related medical diagnoses, the digital processing of the fundus images is used to obtain…

Computer Vision and Pattern Recognition · Computer Science 2015-08-06 Amelia Carolina Sparavigna

The need for comprehensive and automated screening methods for retinal image classification has long been recognized. Well-qualified doctors annotated images are very expensive and only a limited amount of data is available for various…

Computer Vision and Pattern Recognition · Computer Science 2021-02-02 Lie Ju , Xin Wang , Xin Zhao , Huimin Lu , Dwarikanath Mahapatra , Paul Bonnington , Zongyuan Ge

Pathology context and expert experience play significant roles in clinical ocular disease diagnosis. Although deep neural networks (DNNs) have good ocular disease recognition results, they often ignore exploring the clinical pathology…

Computer Vision and Pattern Recognition · Computer Science 2026-01-01 Zunjie Xiao , Xiaoqing Zhang , Risa Higashita , Jiang Liu
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