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The Hillel Yaffe Age Related Macular Degeneration (HYAMD) dataset is a longitudinal collection of 1,560 Digital Fundus Images (DFIs) from 325 patients examined at the Hillel Yaffe Medical Center (Hadera, Israel) between 2021 and 2024. The…

Image and Video Processing · Electrical Eng. & Systems 2025-05-08 Meishar Meisel , Benjamin A. Cohen , Meital Baskin , Beatrice Tiosano , Joachim A. Behar , Eran Berkowitz

Paleness or pallor is a manifestation of blood loss or low hemoglobin concentrations in the human blood that can be caused by pathologies such as anemia. This work presents the first automated screening system that utilizes pallor site…

Computer Vision and Pattern Recognition · Computer Science 2017-03-20 Sohini Roychowdhury , Donny Sun , Matthew Bihis , Johnny Ren , Paul Hage , Humairat H. Rahman

The growing burden of myopia and retinal diseases necessitates more accessible and efficient eye screening solutions. This study presents a compact, dual-function optical device that integrates fundus photography and refractive error…

Image and Video Processing · Electrical Eng. & Systems 2025-04-29 Boyuan Peng , Jiaju Chen , Yiwei Zhang , Cuiyi Peng , Junyang Li , Jiaming Deng , Peiwu Qin

Age-related Macular Degeneration (AMD) is a progressive visual impairment affecting millions of individuals. Since there is no current treatment for the disease, the only means of improving the lives of individuals suffering from the…

Image and Video Processing · Electrical Eng. & Systems 2019-10-18 Prithul Aniruddha , Nasif Zaman , Alireza Tavakkoli , Stewart Zuckerbrod

Glaucoma is the leading cause of preventable, irreversible blindness world-wide. The disease can remain asymptomatic until severe, and an estimated 50%-90% of people with glaucoma remain undiagnosed. Glaucoma screening is recommended for…

There has been much progress in data-driven artificial intelligence technology for medical image analysis in the last decades. However, it still remains challenging due to its distinctive complexity of acquiring and annotating image data,…

Computer Vision and Pattern Recognition · Computer Science 2021-06-30 Chao Gou , Tianyu Shen , Wenbo Zheng , Huadan Xue , Hui Yu , Qiang Ji , Zhengyu Jin , Fei-Yue Wang

We present a summary of transfer learning based methods for several challenging myopic fundus image analysis tasks including classification of pathological and non-pathological myopia,localisation of fovea,and segmentation of optic disc.By…

Image and Video Processing · Electrical Eng. & Systems 2019-08-02 Ruitao Xie , Libo Liu , Jingxin Liu , Connor S Qiu

The use of fundus images for the early screening of eye diseases is of great clinical importance. Due to its powerful performance, deep learning is becoming more and more popular in related applications, such as lesion segmentation,…

Image and Video Processing · Electrical Eng. & Systems 2021-01-26 Tao Li , Wang Bo , Chunyu Hu , Hong Kang , Hanruo Liu , Kai Wang , Huazhu Fu

With the advancements in medical artificial intelligence (AI), fundus image classifiers are increasingly being applied to assist in ophthalmic diagnosis. While existing classification models have achieved high accuracy on specific fundus…

Computer Vision and Pattern Recognition · Computer Science 2025-04-02 Yuzhuo Zhou , Chi Liu , Sheng Shen , Siyu Le , Liwen Yu , Sihan Ouyang , Zongyuan Ge

Portable medical imaging (PMI) has emerged as an important solution for point-of-care diagnosis in emergency, rural, and resource-limited settings where conventional imaging infrastructure is not readily available. Modalities such as…

Image and Video Processing · Electrical Eng. & Systems 2026-04-20 Yassine Habchi , Hamza Kheddar , Muhammad Ali Qureshi , Mohamed Seghier , Azeddine Beghdadi

Automatic clinical diagnosis of retinal diseases has emerged as a promising approach to facilitate discovery in areas with limited access to specialists. Based on the fact that fundus structure and vascular disorders are the main…

Computer Vision and Pattern Recognition · Computer Science 2018-11-05 C. -H. Huck Yang , Fangyu Liu , Jia-Hong Huang , Meng Tian , Hiromasa Morikawa , I-Hung Lin , Yi-Chieh Liu , Hao-Hsiang Yang , Jesper Tegner

Medical image registration is a fundamental task in medical image analysis, aiming to establish spatial correspondences between paired images. However, existing unsupervised deformable registration methods rely solely on intensity-based…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Hao Xu , Tengfei Xue , Jianan Fan , Dongnan Liu , Yuqian Chen , Fan Zhang , Carl-Fredrik Westin , Ron Kikinis , Lauren J. O'Donnell , Weidong Cai

Diabetic retinopathy (DR) is the result of a complication of diabetes affecting the retina. It can cause blindness, if left undiagnosed and untreated. An ophthalmologist performs the diagnosis by screening each patient and analyzing the…

Image and Video Processing · Electrical Eng. & Systems 2021-10-18 Melissa delaPava , Hernán Ríos , Francisco J. Rodríguez , Oscar J. Perdomo , Fabio A. González

Childhood myopia constitutes a significant global health concern. It exhibits an escalating prevalence and has the potential to evolve into severe, irreversible conditions that detrimentally impact familial well-being and create substantial…

Computer Vision and Pattern Recognition · Computer Science 2025-04-16 Mengtian Kang , Yansong Hu , Shuo Gao , Yuanyuan Liu , Hongbei Meng , Xuemeng Li , Xuhang Chen , Hubin Zhao , Jing Fu , Guohua Hu , Wei Wang , Yanning Dai , Arokia Nathan , Peter Smielewski , Ningli Wang , Shiming Li

Age-related macular degeneration (AMD) is a degenerative disorder affecting the macula, a key area of the retina for visual acuity. Nowadays, it is the most frequent cause of blindness in developed countries. Although some promising…

Image and Video Processing · Electrical Eng. & Systems 2022-12-06 José Morano , Álvaro S. Hervella , José Rouco , Jorge Novo , José I. Fernández-Vigo , Marcos Ortega

Diabetic retinopathy is one of the leading causes of preventable blindness in the world. Its earliest sign are red lesions, a general term that groups both microaneurysms and hemorrhages. In daily clinical practice, these lesions are…

Computer Vision and Pattern Recognition · Computer Science 2017-10-16 José Ignacio Orlando , Elena Prokofyeva , Mariana del Fresno , Matthew B. Blaschko

Glaucoma is a severe blinding disease, for which automatic detection methods are urgently needed to alleviate the scarcity of ophthalmologists. Many works have proposed to employ deep learning methods that involve the segmentation of optic…

Image and Video Processing · Electrical Eng. & Systems 2022-09-26 Yanni Wang , Gang Yang , Dayong Ding , Jianchun Zao

Nucleus segmentation is an important analysis task in digital pathology. However, methods for automatic segmentation often struggle with new data from a different distribution, requiring users to manually annotate nuclei and retrain…

Image and Video Processing · Electrical Eng. & Systems 2025-06-03 Titus Griebel , Anwai Archit , Constantin Pape

Previous approaches using deep learning algorithms to classify glaucomatous damage on fundus photographs have been limited by the requirement for human labeling of a reference training set. We propose a new approach using spectral-domain…

Computer Vision and Pattern Recognition · Computer Science 2018-10-25 Felipe A. Medeiros , Alessandro A. Jammal , Atalie C. Thompson

Deep learning underlies most modern approaches and tools in computer vision, including biomedical imaging. However, for interactive semantic segmentation (often called pixel classification in this context) and interactive object-level…

Computer Vision and Pattern Recognition · Computer Science 2026-03-23 Carolin Teuber , Anwai Archit , Tobias Boothe , Peter Ditte , Jochen Rink , Constantin Pape