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It is of great significance to identify the nonhomogeneous distribution of material properties in human tissues for different clinical and medical applications. This leads to the requirement of solving an inverse problem in elasticity. The…

Medical Physics · Physics 2022-11-04 Jianwei Deng , Xu Guo , Yue Mei , Stephane Avril

In this work, we propose a new paradigm of iterative model-based reconstruction algorithms for providing real-time solution for zooming-in and refining a region of interest in medical and clinical tomographic images. This algorithmic…

Image and Video Processing · Electrical Eng. & Systems 2025-12-01 Junqi Tang , Guixian Xu , Jinglai Li

In this paper, we introduce a novel approach that combines multiresolution (MR) techniques with the flux reconstruction (FR) method to accurately and effciently simulate compressible flows. We achieve further enhancements in effciency…

Fluid Dynamics · Physics 2023-06-21 Yixuan Lian , Jinsheng Cai , Shucheng Pan

Fast and accurate reconstruction of magnetic resonance (MR) images from under-sampled data is important in many clinical applications. In recent years, deep learning-based methods have been shown to produce superior performance on MR image…

Image and Video Processing · Electrical Eng. & Systems 2021-03-12 Pengfei Guo , Puyang Wang , Jinyuan Zhou , Shanshan Jiang , Vishal M. Patel

Compressed sensing fluorescence microscopy (CS-FM) proposes a scheme whereby less measurements are collected during sensing and reconstruction is performed to recover the image. Much work has gone into optimizing the sensing and…

Image and Video Processing · Electrical Eng. & Systems 2021-07-13 Alan Q. Wang , Aaron K. LaViolette , Leo Moon , Chris Xu , Mert R. Sabuncu

Conventional 2D fluorescence imaging in glioma surgery cannot separate intrinsic fluorophore strength from attenuation with depth, creating depth-intensity ambiguity that can compromise assessment of residual tumour and fluorescence based…

Medical Physics · Physics 2026-04-07 Yucheng Bian , Sebastien Ourselin , Yijing Xie

Fourier Ptychographic Microscopy (FPM) is an imaging procedure that overcomes the traditional limit on Space-Bandwidth Product (SBP) of conventional microscopes through computational means. It utilizes multiple images captured using a low…

Computer Vision and Pattern Recognition · Computer Science 2022-08-17 Atreyee Saha , Salman S Khan , Sagar Sehrawat , Sanjana S Prabhu , Shanti Bhattacharya , Kaushik Mitra

Fluorescence lifetime imaging (FLI) is an important technique for studying cellular environments and molecular interactions, but its real-time application is limited by slow data acquisition, which requires capturing large time-resolved…

Image and Video Processing · Electrical Eng. & Systems 2024-10-03 Ismail Erbas , Vikas Pandey , Aporva Amarnath , Naigang Wang , Karthik Swaminathan , Stefan T. Radev , Xavier Intes

Recovering high-resolution structural and compositional information from coherent X-ray measurements involves solving coupled, nonlinear, and ill-posed inverse problems. Ptychography reconstructs a complex transmission function from…

Numerical Analysis · Mathematics 2026-05-13 Chengru Eric Zou , Elle Buser , Zichao Wendy Di , Yuanzhe Xi

We report the cell biological applications of a recently developed multiphoton fluorescence lifetime imaging microscopy system using a streak camera (StreakFLIM). The system was calibrated with standard fluorophore specimens and was shown…

Cell Behavior · Quantitative Biology 2009-11-10 R. V. Krishnan , Eva Biener , Jian-Hua Zhang , Robert Heckel , Brian Herman

In structure-based virtual screening, it is often necessary to evaluate the binding free energy of protein-ligand complexes by considering not only molecular conformations but also how these structures shift and rotate in space. The number…

Quantum Physics · Physics 2025-07-25 Pei-Kun Yang

A variety of recent imaging techniques are able to beat the diffraction limit in fluorescence microcopy by activating and localizing subsets of the fluorescent molecules in the specimen, and repeating this process until all of the molecules…

Optics · Physics 2010-08-27 Alexander R. Small

Deep neural networks have been applied to improve the image quality of fluorescence microscopy imaging. Previous methods are based on convolutional neural networks (CNNs) which generally require more time-consuming training of separate…

Fourier Ptychographic Microscopy (FPM) is a recent technique to overcome the diffraction limit of a low numerical aperture (NA) objective lens by algorithmic post-processing of several lower resolved images. It can increase the…

Many applications in computational and experimental fluid mechanics require effective methods for reconstructing the flow fields from limited sensor data. However, this task remains a significant challenge because the measurement operator,…

Fluid Dynamics · Physics 2024-11-22 Phong C. H. Nguyen , Joseph B. Choi , Quang-Trung Luu

Chlorophyll fluorescence (CF) is a key indicator to study plant physiology or photosynthesis efficiency. Conventionally, CF is characterized by fluorometers, which only allows ensemble measurement through wide-field detection. For imaging…

Biological Physics · Physics 2016-11-10 Yi-Chin Tseng , Shi-Wei Chu

While time-frequency analysis provides rich representations of multicomponent signals, current decomposition methods often overlook the morphological structure where components manifest as distinct regions. This study introduces…

Signal Processing · Electrical Eng. & Systems 2025-11-26 Wei Zhou , Wei-Jian Li , Desen Zhu , Hongbin Xu , Wei-Xin Ren

The computational imaging technique of Fourier Ptychographic Microscopy (FPM) enables high-resolution imaging with a wide field of view and can serve as an extremely valuable tool, e.g. in the classification of cells in medical…

Image and Video Processing · Electrical Eng. & Systems 2025-08-25 Navya Sonal Agarwal , Jan Philipp Schneider , Kanchana Vaishnavi Gandikota , Syed Muhammad Kazim , John Meshreki , Ivo Ihrke , Michael Moeller

Fourier ptychography microscopy(FP) is a recently developed computational imaging approach for microscopic super-resolution imaging. By turning on each light-emitting-diode (LED) located on different position on the LED array sequentially…

Optics · Physics 2022-02-22 Delong Yang , Shaohui Zhang , Chuanjian Zheng , Guocheng Zhou , Lei Cao , Yao Hu , Qun Hao

Recovery rate prediction plays a pivotal role in bond investment strategies by enhancing risk assessment, optimizing portfolio allocation, improving pricing accuracy, and supporting effective credit risk management. However, accurate…

Computational Finance · Quantitative Finance 2026-01-27 Ying Chen , Paul Griffin , Paolo Recchia , Lei Zhou , Hongrui Zhang