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It is not currently possible to create a living organism ab initio due to the overwhelming complexity of biological systems. In fact, the origin of life mechanism, this being how biological organisms form from non-living matter, is unknown.…

Earth and Planetary Astrophysics · Physics 2021-04-09 Darius Modirrousta-Galian , Giovanni Maddalena

When a large number of similar entities interact among each other and with their environment at a low scale, unexpected outcomes at higher spatio-temporal scales might spontaneously arise. This nontrivial phenomenon, known as emergence,…

Physics and Society · Physics 2022-05-25 Oriol Artime , Manlio De Domenico

A simple, heuristic formula with parallels to the Drake Equation is introduced to help focus discussion on open questions for the origins of life in a planetary context. This approach indicates a number of areas where quantitative progress…

Earth and Planetary Astrophysics · Physics 2016-08-17 Caleb Scharf , Leroy Cronin

We use a probability theory framework to discuss the search for biosignatures. This perspective allows us to analyse the potential for different biosignatures to provide convincing evidence of extraterrestrial life and to formalise…

Earth and Planetary Astrophysics · Physics 2025-08-28 Rudy Arthur , Arwen E. Nicholson , Nathan J. Mayne

The origin of life is shrouded in mystery, with few surviving clues, obscured by evolutionary competition. Previous reviews have touched on the complementary approaches of top-down and bottom-up synthetic biology to augment our…

Populations and Evolution · Quantitative Biology 2022-07-18 Ivan Ivanov , Stoyan K. Smoukov , Ehsan Nourafkan , Katharina Landfester , Petra Schwille

To assess the number of life-bearing worlds in astrophysical environments, it is necessary to take the intertwined processes of abiogenesis (birth), extinction (death), and transfer of life (migration) into account. We construct a…

Earth and Planetary Astrophysics · Physics 2023-06-21 Manasvi Lingam , Claudio Grimaldi , Amedeo Balbi

Bayesian Inference is a powerful approach to data analysis that is based almost entirely on probability theory. In this approach, probabilities model {\it uncertainty} rather than randomness or variability. This thesis is composed of a…

Astrophysics · Physics 2008-09-08 Brendon J. Brewer

Life is a discrete, stochastic phenomena : for a biological organism, the time of the two most important events of its life (reproduction and death) is random and these events change the number of individuals of the species by single units.…

Biological Physics · Physics 2013-06-20 Bahram Houchmandzadeh

A wide variety of scenarios for the origin of life have been proposed, with many influencing the prevalence and distribution of biosignatures across exoplanet populations. This relationship suggests these scenarios can be tested by…

It is fair to say that the deepest mystery in our understanding of nature is the birth of our universe. Much of the dilemma over the last decades comes from the extraordinarily small probability that the universe started with the high…

High Energy Physics - Theory · Physics 2008-09-25 Laura Mersini-Houghton

It is well known that life on Earth alters its environment over evolutionary and geological timescales. An important open question is whether this is a result of evolutionary optimization or a universal feature of life. In the latter case,…

Adaptation and Self-Organizing Systems · Physics 2017-04-26 Cole Mathis , Tanmoy Bhattacharya , Sara Imari Walker

Since its inception six decades ago, astrobiology has diversified immensely to encompass several scientific questions including the origin and evolution of Terran life, the organic chemical composition of extraterrestrial objects, and the…

Biological activities are often seen entrained onto the day-night and other celestial mechanical cycles (e.g., seasonal and lunar), but studies on the origin of life have largely not accounted for such periodic external environmental…

Chaotic Dynamics · Physics 2024-08-21 Fan Zhang

Any search for present or past life beyond Earth should consider the initial processes and related environmental controls that might have led to its start. As on Earth, such an understanding lies well beyond how simple organic molecules…

Instrumentation and Methods for Astrophysics · Physics 2020-08-12 Timothy W. Lyons , Karyn Rogers , Ramanarayanan Krishnamurthy , Loren Williams , Simone Marchi , Edward Schwieterman , Noah Planavsky , Christopher Reinhard

One of the major goals for astronomy in the next decades is the remote search for biosignatures (i.e.\ the spectroscopic evidence of biological activity) in exoplanets. Here, we adopt a Bayesian statistical framework to discuss the…

Earth and Planetary Astrophysics · Physics 2020-08-19 Amedeo Balbi , Claudio Grimaldi

Is life most likely to emerge at the present cosmic time near a star like the Sun? We address this question by calculating the relative formation probability per unit time of habitable Earth-like planets within a fixed comoving volume of…

Cosmology and Nongalactic Astrophysics · Physics 2016-08-31 Abraham Loeb , Rafael A. Batista , David Sloan

I describe a new method of estimating the prevalence of life in the Universe, based on the fact that more chemically complex environments are more rare. The paper makes three main claims: (1) There is a statistically significant (inverse)…

Earth and Planetary Astrophysics · Physics 2024-12-03 Lukasz Lamza

Bayesian probability theory is used to analyze the oft-made assumption that humans are typical observers in the universe. Some theoretical calculations make the {\it selection fallacy} that we are randomly chosen from a class of objects by…

High Energy Physics - Theory · Physics 2008-11-26 James B. Hartle , Mark Srednicki

The improbability of a spontaneously generated self-assembling molecule has suggested that life began with a set of simpler, collectively replicating elements, such as an enclosed autocatalytic set of polymers (or protocell). Since…

Adaptation and Self-Organizing Systems · Physics 2013-08-26 Liane Gabora

Due to recent advances in synthetic biology and artificial life, the origin of life is currently a hot topic of research. We review the literature and argue that the two traditionally competing "replicator-first" and "metabolism-first"…

Artificial Intelligence · Computer Science 2013-11-21 Tom Froese , Nathaniel Virgo , Takashi Ikegami