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Research investigating the origins of life usually focuses on exploring possible life-bearing chemistries in the pre-biotic Earth, or else on synthetic approaches. Little work has been done exploring fundamental issues concerning the…

Populations and Evolution · Quantitative Biology 2015-06-24 Christoph Adami

The path toward the emergence of life in our biosphere involved several key events allowing for the persistence, reproduction and evolution of molecular systems. All these processes took place in a given environmental context and required…

Disordered Systems and Neural Networks · Physics 2025-04-14 Ricard Solé , Manlio De Domenico

The hypothesis that the rapid appearance of life on Earth justifies the belief that life is widespread in the universe has been investigated statistically by Lineweaver and Davis. However, a rapid appearance could also be interpreted as…

Astrophysics · Physics 2009-11-10 P. C. W. Davies

The origin of life on Earth via the spontaneous emergence of a protocell prior to Darwinian evolution remains a fundamental open question in physics and chemistry. Here, we develop a conceptual framework based on information theory and…

Populations and Evolution · Quantitative Biology 2025-12-23 Robert G. Endres

The observable universe is necessarily hospitable for life. There are indications, however, that the laws of physics and cosmological parameters need not take the form and values observed, and if they were slightly different life could not…

General Physics · Physics 2012-07-24 Colin S. Coleman

In this article, we attempt to convince the reader that the origin of life was such an exceptionally unlikely event that it probably has never occurred elsewhere. This involves an explicit calculation using the laws of physics which, while…

High Energy Physics - Phenomenology · Physics 2025-05-12 Paul Howard Frampton

Abiotic emergence of ordered information stored in the form of RNA is an important unresolved problem concerning the origin of life. A polymer longer than 40--100 nucleotides is necessary to expect a self-replicating activity, but the…

Populations and Evolution · Quantitative Biology 2020-02-04 Tomonori Totani

According to the "hard-steps" model, the origin of humanity required "successful passage through a number of intermediate steps" (so-called "hard" or "critical" steps) that were intrinsically improbable with respect to the total time…

Populations and Evolution · Quantitative Biology 2025-02-18 Daniel B. Mills , Jennifer L. Macalady , Adam Frank , Jason T. Wright

Although many solar systems have been discovered, only one example of life is known. Thus, terrestrial life represents merely one data point. Consequently, extrapolating from terrestrial life to life elsewhere in the galaxy and beyond is…

Popular Physics · Physics 2024-03-22 Ian von Hegner

Finding life on exoplanets from telescopic observations is an ultimate goal of exoplanet science. Life produces gases and other substances, such as pigments, which can have distinct spectral or photometric signatures. Whether or not life is…

The origins of life stands among the great open scientific questions of our time. While a number of proposals exist for possible starting points in the pathway from non-living to living matter, these have so far not achieved states of…

Populations and Evolution · Quantitative Biology 2017-05-24 Sara I. Walker

The origin of life is often framed primarily as a chemical problem, yet life's defining feature is evolution. Advances in geochemistry, prebiotic chemistry, and molecular biology have produced diverse scenarios for the emergence of genomes,…

Estimates of the time at which life arose on Earth make use of two types of evidence. First, astrophysical and geophysical studies provide a timescale for the formation of Earth and the Moon, for large impact events on early Earth, and for…

Earth and Planetary Astrophysics · Physics 2018-08-30 Ben K. D. Pearce , Andrew S. Tupper , Ralph E. Pudritz , Paul G. Higgs

Despite great advances in our understanding of the formation of the Solar System, the evolution of the Earth, and the chemical basis for life, we are not much closer than the ancient Greeks to an answer of whether life has arisen and…

Astrophysics · Physics 2007-05-23 Eric Gaidos , Franck Selsis

A simple stochastic model for evolution, based upon the need to pass a sequence of n critical steps (Carter 1983, Watson 2008) is applied to both terrestrial and extraterrestrial origins of life. In the former case, the time at which humans…

Earth and Planetary Astrophysics · Physics 2011-04-22 Michael McCabe , Holly Lucas

In extracting predictions from theories that describe a multiverse, we face the difficulty that we must assess probability distributions over possible observations, prescribed not just by an underlying theory, but by a theory together with…

History and Philosophy of Physics · Physics 2015-06-18 Feraz Azhar

Extracting predictions from cosmological theories that describe a multiverse, for what we are likely to observe in our domain, is crucial to establishing the validity of these theories. One way to extract such predictions is from…

History and Philosophy of Physics · Physics 2016-09-12 Feraz Azhar

We propose a novel definition of life in terms of which its emergence in the universe is expected, and its ever-creative open-ended evolution is entailed by no law. Living organisms are Kantian Wholes that achieve Catalytic Closure,…

Populations and Evolution · Quantitative Biology 2024-04-11 Stuart Kauffman , Andrea Roli

Astrobiology, the study of life as a planetary phenomenon, aims to understand the fundamental nature of life on earth and the possibility of life elsewhere. To achieve this goal, astrobiologists have initiated unprecedented communication…

Biosystems contain an almost infinite amount of vital important details, which together ensure their life. There are, however, some common structures and reactions in the systems: the homochirality of carbohydrates and proteins, the…

Biomolecules · Quantitative Biology 2018-03-06 Soren Toxvaerd