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The $\beta$-relaxation associated with the sub-glass transition temperature ($T_{\text{g},\beta}$) is attributed to fast, localised molecular motions which can occur below the primary glass transition temperature ($T_{g\alpha}$). Despite…

Biological Physics · Physics 2019-11-06 Maarten Batens , Talia A. Shmool , Jan Massant , J. Axel Zeitler , Guy Van den Mooter

Many glass-forming fluids exhibit a remarkable thermodynamic scaling in which dynamic properties, such as the viscosity, the relaxation time, and the diffusion constant, can be described under different thermodynamic conditions in terms of…

Soft Condensed Matter · Physics 2015-06-16 Wen-Sheng Xu , Karl F. Freed

Normal mode analysis is a widely used technique for reconstructing conformational changes of proteins from the knowledge of native structures. In this Letter, we investigate to what extent normal modes capture the salient features of the…

Statistical Mechanics · Physics 2015-05-13 Francesco Piazza , Paolo De Los Rios , Fabio Cecconi

Water scarcity has required constant water recycling, leading to a decline in water quality, further exacerbated by high concentrations of fine particles that reduce the efficiency of solid-liquid separation systems. Inclined settlers offer…

Fluid Dynamics · Physics 2025-04-18 Cristian Reyes , Cristobal Arratia , Christian Ihle

Recent experiments have reported lower critical solution temperature (LCST) phase behavior of aqueous solutions of proteins induced by multivalent ions, where the solution phase separates upon heating. This phenomenon is linked to complex…

Soft Condensed Matter · Physics 2021-12-21 Anil Kumar Sahoo , Frank Schreiber , Roland R. Netz , Prabal K. Maiti

This paper discusses the stability of an equilibrium point of an ordinary differential equation (ODE) arising from a feed-forward position control for a musculoskeletal system. The studied system has a link, a joint and two muscles with…

Dynamical Systems · Mathematics 2019-04-30 Takahiro Kosugi , Hitoshi Kino , Masaaki Goto , Yuki Matsutani

Membrane proteins deform the surrounding lipid bilayer, which can lead to membrane-mediated interactions between neighboring proteins. Using the mechanosensitive channel of large conductance (MscL) as a model system, we demonstrate how the…

Biomolecules · Quantitative Biology 2016-11-03 Osman Kahraman , William S. Klug , Christoph A. Haselwandter

A previously established multiscale population genetics model states that fitness can be inferred from the physical properties of proteins under the physiological assumption that a loss of stability by any protein confers the lethal…

Biomolecules · Quantitative Biology 2009-06-03 Peiqiu Chen , Eugene I. Shakhnovich

Elastic netwok models coarse grain proteins into a network of residue beads connected by springs. We add dissipative dynamics to this mechanical system by applying overdamped Langevin equations of motion to normal-mode vibrations of the…

Biological Physics · Physics 2015-06-05 Daniel R. Martin , Dmitry V. Matyushov

As an example of topic where biology and physics meet, we present the issue of protein folding and stability, and the development of thermodynamics-based bioinformatics tools that predict the stability and thermal resistance of proteins and…

Biomolecules · Quantitative Biology 2016-03-15 Fabrizio Pucci , Marianne Rooman

The effects of a dispersed particulate phase on the onset of Rayleigh-B\'enard convection in a fluid layer is studied theoretically by means of a two-fluid Eulerian modelization. The particles are non-Brownian, spherical, with inertia and…

Fluid Dynamics · Physics 2024-12-24 Saad Raza , Silvia C. Hirata , Enrico Calzavarini

Understanding interactions between membranes requires measurements on well-controlled systems close to natural conditions, in which fluctuations play an important role. We have determined, by grazing incidence X-ray scattering, the…

Network theory is rapidly changing our understanding of complex systems, but the relevance of topological features for the dynamic behavior of metabolic networks, food webs, production systems, information networks, or cascade failures of…

Disordered Systems and Neural Networks · Physics 2007-05-23 Dirk Helbing , Stefan Lämmer

We study the effect of membrane proteins on the shape, composition and thermodynamic stability of the surrounding membrane. When the coupling between membrane composition and curvature is strong enough the nearby composition and shape both…

Soft Condensed Matter · Physics 2015-03-11 S. Alex Rautu , George Rowlands , Matthew S. Turner

We study statistical properties of interacting protein-like surfaces and predict two strong, related effects: (i) statistically enhanced self-attraction of proteins; (ii) statistically enhanced attraction of proteins with similar…

Biomolecules · Quantitative Biology 2007-05-23 D. B. Lukatsky , B. E. Shakhnovich , J. Mintseris , E. I. Shakhnovich

We consider multi-chain protein native structures and propose a criterion that determines whether two chains in the system are entangled or not. The criterion is based on the behavior observed by pulling at both temini of each chain…

Biomolecules · Quantitative Biology 2017-07-19 Yani Zhao , Mateusz Chwastyk , Marek Cieplak

We consider the transport of gas in long pipes and pipeline networks for which the dynamics are dominated by friction at the pipe walls. The governing equations can be formulated as an abstract dissipative Hamiltonian system which allows us…

Analysis of PDEs · Mathematics 2023-04-11 Herbert Egger , Jan Giesselmann

Soft colloids allow to explore high density states well beyond random close packing. An important open question is whether softness controls the dynamics under these dense conditions. While experimental works reported conflicting results,…

Soft Condensed Matter · Physics 2021-06-08 Nicoletta Gnan , Emanuela Zaccarelli

We present a quantitative confocal-microscopy study of the transient and final microstructure of particle-stabilised emulsions formed via demixing in a binary liquid. To this end, we have developed an image-analysis method that relies on…

Soft Condensed Matter · Physics 2010-11-04 Job H J Thijssen , Paul S Clegg

In this study, we present a method of pattern mining based on network theory that enables the identification of protein structures or complexes from synthetic volume densities, without the knowledge of predefined templates or human biases…

Quantitative Methods · Quantitative Biology 2022-10-18 August George , Doo Nam Kim , Trevor Moser , Ian T. Gildea , James E. Evans , Margaret S. Cheung