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Convolutional Neural Networks (CNNs) have seen significant performance improvements in recent years. However, due to their size and complexity, they function as black-boxes, leading to transparency concerns. State-of-the-art saliency…

Computer Vision and Pattern Recognition · Computer Science 2025-06-04 Antonio De Santis , Riccardo Campi , Matteo Bianchi , Marco Brambilla

The success of recent deep convolutional neural networks (CNNs) depends on learning hidden representations that can summarize the important factors of variation behind the data. However, CNNs often criticized as being black boxes that lack…

Computer Vision and Pattern Recognition · Computer Science 2018-06-27 Bolei Zhou , David Bau , Aude Oliva , Antonio Torralba

Neural network models have achieved state-of-the-art performances in a wide range of natural language processing (NLP) tasks. However, a long-standing criticism against neural network models is the lack of interpretability, which not only…

Computation and Language · Computer Science 2021-10-26 Xiaofei Sun , Diyi Yang , Xiaoya Li , Tianwei Zhang , Yuxian Meng , Han Qiu , Guoyin Wang , Eduard Hovy , Jiwei Li

XAI gained considerable importance in recent years. Methods based on prototypical case-based reasoning have shown a promising improvement in explainability. However, these methods typically rely on additional post-hoc saliency techniques to…

Computer Vision and Pattern Recognition · Computer Science 2025-10-02 Steffen Meinert , Philipp Schlinge , Nils Strodthoff , Martin Atzmueller

Saliency maps can explain a neural model's predictions by identifying important input features. They are difficult to interpret for laypeople, especially for instances with many features. In order to make them more accessible, we formalize…

Computation and Language · Computer Science 2023-06-08 Nils Feldhus , Leonhard Hennig , Maximilian Dustin Nasert , Christopher Ebert , Robert Schwarzenberg , Sebastian Möller

Adopting Convolutional Neural Networks (CNNs) in the daily routine of primary diagnosis requires not only near-perfect precision, but also a sufficient degree of generalization to data acquisition shifts and transparency. Existing CNN…

Computer Vision and Pattern Recognition · Computer Science 2023-06-22 Mara Graziani , Sebastian Otalora , Stephane Marchand-Maillet , Henning Muller , Vincent Andrearczyk

There is an increasing interest in the use of Deep Learning (DL) based methods as a supporting analytical framework in oncology. However, most direct applications of DL will deliver models with limited transparency and explainability, which…

Quantitative Methods · Quantitative Biology 2023-01-26 Magdalena Wysocka , Oskar Wysocki , Marie Zufferey , Dónal Landers , André Freitas

Interpretability is crucial to enhance trust in machine learning models for medical diagnostics. However, most state-of-the-art image classifiers based on neural networks are not interpretable. As a result, clinicians often resort to known…

Binarized Neural Networks (BNNs) have the potential to revolutionize the way that deep learning is carried out in edge computing platforms. However, the effectiveness of interpretability methods on these networks has not been assessed. In…

Computer Vision and Pattern Recognition · Computer Science 2021-06-24 Amy Widdicombe , Simon J. Julier

Exponential growth in Electronic Healthcare Records (EHR) has resulted in new opportunities and urgent needs for discovery of meaningful data-driven representations and patterns of diseases in Computational Phenotyping research. Deep…

Machine Learning · Statistics 2015-12-14 Zhengping Che , Sanjay Purushotham , Robinder Khemani , Yan Liu

Despite the recent progress in Graph Neural Networks (GNNs), it remains challenging to explain the predictions made by GNNs. Existing explanation methods mainly focus on post-hoc explanations where another explanatory model is employed to…

Machine Learning · Computer Science 2021-12-03 Zaixi Zhang , Qi Liu , Hao Wang , Chengqiang Lu , Cheekong Lee

The majority of existing post-hoc explanation approaches for machine learning models produce independent, per-variable feature attribution scores, ignoring a critical inherent characteristics of homogeneously structured data, such as visual…

Machine Learning · Computer Science 2023-02-14 Vadim Borisov , Gjergji Kasneci

Breast cancer is a relatively common cancer among gynecological cancers. Its diagnosis often relies on the pathology of cells in the lesion. The pathological diagnosis of breast cancer not only requires professionals and time, but also…

Image and Video Processing · Electrical Eng. & Systems 2024-04-15 MingXuan Xiao , Yufeng Li , Xu Yan , Min Gao , Weimin Wang

Recent efforts in Machine Learning (ML) interpretability have focused on creating methods for explaining black-box ML models. However, these methods rely on the assumption that simple approximations, such as linear models or decision-trees,…

Machine Learning · Computer Science 2019-06-13 Owen Lahav , Nicholas Mastronarde , Mihaela van der Schaar

With the broader and highly successful usage of machine learning in industry and the sciences, there has been a growing demand for Explainable AI. Interpretability and explanation methods for gaining a better understanding about the problem…

Machine Learning · Computer Science 2021-02-26 Wojciech Samek , Grégoire Montavon , Sebastian Lapuschkin , Christopher J. Anders , Klaus-Robert Müller

We introduce provenance networks, a novel class of neural models designed to provide end-to-end, training-data-driven explainability. Unlike conventional post-hoc methods, provenance networks learn to link each prediction directly to its…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Ali Kayyam , Anusha Madan Gopal , M. Anthony Lewis

Even though deep neural networks (DNNs) achieve state-of-the-art results for a number of problems involving genomic data, getting DNNs to explain their decision-making process has been a major challenge due to their black-box nature. One…

Genomics · Quantitative Biology 2022-12-14 Utku Ozbulak , Solha Kang , Jasper Zuallaert , Stephen Depuydt , Joris Vankerschaver

This paper explores the application of Human-in-the-Loop (HITL) strategies in training machine learning models in the medical domain. In this case a doctor-in-the-loop approach is proposed to leverage human expertise in dealing with large…

Computer Vision and Pattern Recognition · Computer Science 2024-04-01 David Vázquez-Lema , Eduardo Mosqueira-Rey , Elena Hernández-Pereira , Carlos Fernández-Lozano , Fernando Seara-Romera , Jorge Pombo-Otero

Recent years have witnessed an increasing number of interpretation methods being developed for improving transparency of NLP models. Meanwhile, researchers also try to answer the question that whether the obtained interpretation is faithful…

Computation and Language · Computer Science 2020-09-17 Ninghao Liu , Yunsong Meng , Xia Hu , Tie Wang , Bo Long

The lack of interpretability in the field of medical image analysis has significant ethical and legal implications. Existing interpretable methods in this domain encounter several challenges, including dependency on specific models,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Lijie Hu , Songning Lai , Wenshuo Chen , Hongru Xiao , Hongbin Lin , Lu Yu , Jingfeng Zhang , Di Wang