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Multimodal positron emission tomography-computed tomography (PET-CT) is used routinely in the assessment of cancer. PET-CT combines the high sensitivity for tumor detection with PET and anatomical information from CT. Tumor segmentation is…

Image and Video Processing · Electrical Eng. & Systems 2022-06-13 Xiaohang Fu , Lei Bi , Ashnil Kumar , Michael Fulham , Jinman Kim

We are developing a computer-aided detection (CAD) system for the identification of small pulmonary nodules in screening CT scans. The main modules of our system, i.e. a dot-enhancement filter for nodule candidate selection and a neural…

Medical Physics · Physics 2009-04-15 P. Delogu , M. E. Fantacci , I. Gori , A. Preite Martinez , A. Retico , A. Tata

Diffusion models have shown impressive performance for generative modelling of images. In this paper, we present a novel semantic segmentation method based on diffusion models. By modifying the training and sampling scheme, we show that…

Computer Vision and Pattern Recognition · Computer Science 2021-12-28 Julia Wolleb , Robin Sandkühler , Florentin Bieder , Philippe Valmaggia , Philippe C. Cattin

The analysis of multi-modality positron emission tomography and computed tomography (PET-CT) images for computer aided diagnosis applications requires combining the sensitivity of PET to detect abnormal regions with anatomical localization…

Computer Vision and Pattern Recognition · Computer Science 2019-10-29 Ashnil Kumar , Michael Fulham , Dagan Feng , Jinman Kim

In oral cancer diagnostics, the limited availability of annotated datasets frequently constrains the performance of diagnostic models, particularly due to the variability and insufficiency of training data. To address these challenges, this…

Machine Learning · Computer Science 2025-08-11 Yong Oh Lee , JeeEun Kim , Jung Woo Lee

Lung cancer is a leading cause of death in most countries of the world. Since prompt diagnosis of tumors can allow oncologists to discern their nature, type and the mode of treatment, tumor detection and segmentation from CT Scan images is…

Image and Video Processing · Electrical Eng. & Systems 2021-11-18 Farhanaz Farheen , Md. Salman Shamil , Nabil Ibtehaz , M. Sohel Rahman

Deep learning and generative models are advancing rapidly, with synthetic data increasingly being integrated into training pipelines for downstream analysis tasks. However, in medical imaging, their adoption remains constrained by the…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Kyeonghun Kim , Jaehyeok Bae , Youngung Han , Joo Young Bae , Seoyoung Ju , Junsu Lim , Gyeongmin Kim , Nam-Joon Kim , Woo Kyoung Jeong , Ken Ying-Kai Liao , Won Jae Lee , Pa Hong , Hyuk-Jae Lee

Detection of pulmonary nodules on chest CT is an essential step in the early diagnosis of lung cancer, which is critical for best patient care. Although a number of computer-aided nodule detection methods have been published in the…

Computer Vision and Pattern Recognition · Computer Science 2018-07-03 Junjie Zhang , Yong Xia , Yanning Zhang

Accurate lesion segmentation in whole-body PET/CT scans is crucial for cancer diagnosis and treatment planning, but limited datasets often hinder the performance of automated segmentation models. In this paper, we explore the potential of…

Image and Video Processing · Electrical Eng. & Systems 2024-09-13 Lap Yan Lennon Chan , Chenxin Li , Yixuan Yuan

In this work, we present a fully automated lung computed tomography (CT) cancer diagnosis system, DeepLung. DeepLung consists of two components, nodule detection (identifying the locations of candidate nodules) and classification…

Computer Vision and Pattern Recognition · Computer Science 2018-01-30 Wentao Zhu , Chaochun Liu , Wei Fan , Xiaohui Xie

Synthetic data generation in histopathology faces unique challenges: preserving tissue heterogeneity, capturing subtle morphological features, and scaling to unannotated datasets. We present a latent diffusion model that generates realistic…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Saghir Alfasly , Wataru Uegami , MD Enamul Hoq , Ghazal Alabtah , H. R. Tizhoosh

Modern biomedical image analysis using deep learning often encounters the challenge of limited annotated data. To overcome this issue, deep generative models can be employed to synthesize realistic biomedical images. In this regard, we…

Image and Video Processing · Electrical Eng. & Systems 2026-02-23 Yuli Wu , Weidong He , Dennis Eschweiler , Ningxin Dou , Zixin Fan , Shengli Mi , Peter Walter , Johannes Stegmaier

Visual microscopic study of diseased tissue by pathologists has been the cornerstone for cancer diagnosis and prognostication for more than a century. Recently, deep learning methods have made significant advances in the analysis and…

Image and Video Processing · Electrical Eng. & Systems 2022-09-30 Puria Azadi Moghadam , Sanne Van Dalen , Karina C. Martin , Jochen Lennerz , Stephen Yip , Hossein Farahani , Ali Bashashati

Lung cancer, particularly in its advanced stages, remains a leading cause of death globally. Though early detection via low-dose computed tomography (CT) is promising, the identification of high-risk factors crucial for surgical mode…

Image and Video Processing · Electrical Eng. & Systems 2023-08-29 Xiaotong Fu , Xiangyu Meng , Jing Zhou , Ying Ji

Breast-Conserving Surgery (BCS) requires precise intraoperative margin assessment to preserve healthy tissue. Deep Ultraviolet Fluorescence Scanning Microscopy (DUV-FSM) offers rapid, high-resolution surface imaging for this purpose;…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Pouya Afshin , David Helminiak , Tianling Niu , Julie M. Jorns , Tina Yen , Bing Yu , Dong Hye Ye

Lung cancer is the leading cause of cancer deaths. Early detection through low-dose computed tomography (CT) screening has been shown to significantly reduce mortality but suffers from a high false positive rate that leads to unnecessary…

Image and Video Processing · Electrical Eng. & Systems 2019-06-04 Jason L. Causey , Yuanfang Guan , Wei Dong , Karl Walker , Jake A. Qualls , Fred Prior , Xiuzhen Huang

Lung cancer is the leading cause of cancer death worldwide. The best solution for lung cancer is to diagnose the pulmonary nodules in the early stage, which is usually accomplished with the aid of thoracic computed tomography (CT). As deep…

Image and Video Processing · Electrical Eng. & Systems 2023-03-08 Rui Xu , Zhi Liu , Yong Luo , Han Hu , Li Shen , Bo Du , Kaiming Kuang , Jiancheng Yang

Until now, in the wake of the COVID-19 pandemic in 2019, lung diseases, especially diseases such as lung cancer and chronic obstructive pulmonary disease (COPD), have become an urgent global health issue. In order to mitigate the goal…

Image and Video Processing · Electrical Eng. & Systems 2025-02-24 Tianzuo Hu

Accurate segmentation of pulmonary vessels plays a very critical role in diagnosing and assessing various lung diseases. Currently, many automated algorithms are primarily targeted at CTPA (Computed Tomography Pulmonary Angiography) types…

Image and Video Processing · Electrical Eng. & Systems 2025-05-20 Ying Ming , Shaoze Luo , Longfei Zhao , Ruijie Zhao , Bing Li , Qiqi Xu , Wei Song

Lung cancer is a very deadly disease worldwide, and its early diagnosis is crucial for increasing patient survival rates. Computed tomography (CT) scans are widely used for lung cancer diagnosis as they can give detailed lung structures.…

Computer Vision and Pattern Recognition · Computer Science 2025-12-04 Md Rashidul Islam , Bakary Gibba , Altagi Abdallah Bakheit Abdelgadir
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