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Pulmonary nodule detection plays an important role in lung cancer screening with low-dose computed tomography (CT) scans. It remains challenging to build nodule detection deep learning models with good generalization performance due to…

Computer Vision and Pattern Recognition · Computer Science 2020-02-10 Yuemeng Li , Yong Fan

Data availability plays a critical role for the performance of deep learning systems. This challenge is especially acute within the medical image domain, particularly when pathologies are involved, due to two factors: 1) limited number of…

Computer Vision and Pattern Recognition · Computer Science 2018-06-12 Dakai Jin , Ziyue Xu , Youbao Tang , Adam P. Harrison , Daniel J. Mollura

Lung cancer has been one of the major threats across the world with the highest mortalities. Computer-aided detection (CAD) can help in early detection and thus can help increase the survival rate. Accurate lung parenchyma segmentation (to…

Image and Video Processing · Electrical Eng. & Systems 2025-09-18 Muhammad Abdullah , Furqan Shaukat

Collecting and annotating medical images is a time-consuming and resource-intensive task. However, generating synthetic data through models such as Diffusion offers a cost-effective alternative. This paper introduces a new method for the…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Ruochen Pi , Lianlei Shan

Data scarcity in medical imaging poses significant challenges due to privacy concerns. Diffusion models, a recent generative modeling technique, offer a potential solution by generating synthetic and realistic data. However, questions…

Image and Video Processing · Electrical Eng. & Systems 2024-12-24 Abdullah al Nomaan Nafi , Md. Alamgir Hossain , Rakib Hossain Rifat , Md Mahabub Uz Zaman , Md Manjurul Ahsan , Shivakumar Raman

The early detection and nuanced subtype classification of non-small cell lung cancer (NSCLC), a predominant cause of cancer mortality worldwide, is a critical and complex issue. In this paper, we introduce an innovative integration of…

Image and Video Processing · Electrical Eng. & Systems 2024-10-08 Salma Hassan , Hamad Al Hammadi , Ibrahim Mohammed , Muhammad Haris Khan

Lung cancer is the leading cause of cancer-related mortality worldwide. Lung cancer screening (LCS) using annual low-dose computed tomography (CT) scanning has been proven to significantly reduce lung cancer mortality by detecting cancerous…

Computed tomography (CT) generates a stack of cross-sectional images covering a region of the body. The visual assessment of these images for the identification of potential abnormalities is a challenging and time consuming task due to the…

Machine Learning · Statistics 2016-10-03 Petros-Pavlos Ypsilantis , Giovanni Montana

Artificial Intelligence (AI) based image analysis has an immense potential to support diagnostic histopathology, including cancer diagnostics. However, developing supervised AI methods requires large-scale annotated datasets. A potentially…

Early diagnosis of lung cancer is challenging due to biological uncertainty and the limited understanding of the biological mechanisms driving nodule progression. To address this, we propose Nodule-Aligned Multimodal (Latent) Diffusion…

Computer Vision and Pattern Recognition · Computer Science 2026-03-18 James Song , Yifan Wang , Chuan Zhou , Liyue Shen

Lung Cancer is the most common cause of cancer-related death worldwide. Early and automatic diagnosis of Solitary Pulmonary Nodules (SPN) in Computer Tomography (CT) chest scans can provide early treatment as well as doctor liberation from…

Image and Video Processing · Electrical Eng. & Systems 2020-03-31 Ioannis D. Apostolopoulos

While deep learning methods are increasingly being applied to tasks such as computer-aided diagnosis, these models are difficult to interpret, do not incorporate prior domain knowledge, and are often considered as a "black-box." The lack of…

Computer Vision and Pattern Recognition · Computer Science 2018-06-05 Shiwen Shen , Simon X. Han , Denise R. Aberle , Alex A. T. Bui , Willliam Hsu

Lung cancer follow-up is a complex, error prone, and time consuming task for clinical radiologists. Several lung CT scan images taken at different time points of a given patient need to be individually inspected, looking for possible…

Image and Video Processing · Electrical Eng. & Systems 2019-12-24 Xavier Rafael-Palou , Anton Aubanell , Ilaria Bonavita , Mario Ceresa , Gemma Piella , Vicent Ribas , Miguel Ángel González Ballester

Lung cancer is the leading cause of patient mortality in the world. Early diagnosis of malignant pulmonary nodules in CT images can have a significant impact on reducing disease mortality and morbidity. In this work, we propose LMLCC-Net, a…

Image and Video Processing · Electrical Eng. & Systems 2025-11-27 Tasnia Binte Mamun , Adhora Madhuri , Nusaiba Sobir , Taufiq Hasan

This work introduces a new latent diffusion model to generate high-quality 3D chest CT scans conditioned on 3D anatomical masks. The method synthesizes volumetric images of size 256x256x256 at 1 mm isotropic resolution using a single…

Computer Vision and Pattern Recognition · Computer Science 2025-10-22 Anna Oliveras , Roger Marí , Rafael Redondo , Oriol Guardià , Ana Tost , Bhalaji Nagarajan , Carolina Migliorelli , Vicent Ribas , Petia Radeva

Early and accurate diagnosis of interstitial lung diseases (ILDs) is crucial for making treatment decisions, but can be challenging even for experienced radiologists. The diagnostic procedure is based on the detection and recognition of the…

Computer Vision and Pattern Recognition · Computer Science 2018-04-02 Marios Anthimopoulos , Stergios Christodoulidis , Lukas Ebner , Thomas Geiser , Andreas Christe , Stavroula Mougiakakou

A computer-aided detection (CAD) system for the identification of pulmonary nodules in low-dose multi-detector helical CT images with 1.25 mm slice thickness is being developed in the framework of the INFN-supported MAGIC-5 Italian project.…

Medical Physics · Physics 2007-05-23 P. Delogu , M. E. Fantacci , I. Gori , A. Preite Martinez , A. Retico

The accurate diagnosis on pathological subtypes for lung cancer is of significant importance for the follow-up treatments and prognosis managements. In this paper, we propose self-generating hybrid feature network (SGHF-Net) for accurately…

Image and Video Processing · Electrical Eng. & Systems 2024-05-20 Wentao Zhu , Yuan Jin , Gege Ma , Geng Chen , Jan Egger , Shaoting Zhang , Dimitris N. Metaxas

Computer aided diagnostic (CAD) system is crucial for modern med-ical imaging. But almost all CAD systems operate on reconstructed images, which were optimized for radiologists. Computer vision can capture features that is subtle to human…

Computer Vision and Pattern Recognition · Computer Science 2018-10-04 Dufan Wu , Kyungsang Kim , Bin Dong , Georges El Fakhri , Quanzheng Li

Pulmonary nodules are critical indicators for the early diagnosis of lung cancer, making their detection essential for timely treatment. However, traditional CT imaging methods suffered from cumbersome procedures, low detection rates, and…

Image and Video Processing · Electrical Eng. & Systems 2025-01-29 Guohui Cai , Ruicheng Zhang , Hongyang He , Zeyu Zhang , Daji Ergu , Yuanzhouhan Cao , Jinman Zhao , Binbin Hu , Zhinbin Liao , Yang Zhao , Ying Cai