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Background: Biomedical research projects deal with data management requirements from multiple sources like funding agencies' guidelines, publisher policies, discipline best practices, and their own users' needs. We describe functional and…

Analysis of genomics data is central to nearly all areas of modern biology. Despite significant progress in artificial intelligence (AI) and computational methods, these technologies require significant human oversight to generate novel and…

The human genome is incredibly information-rich, consisting of approximately 25,000 protein-coding genes spread out over 3.2 billion nucleotide base pairs contained within 24 unique chromosomes. The genome is important in maintaining…

Human-Computer Interaction · Computer Science 2023-08-28 Gunnar Reiske , Sungwon In , Yalong Yang

Entity Linking is the task of matching a mention to an entity in a given knowledge base (KB). It contributes to annotating a massive amount of documents existing on the Web to harness new facts about their matched entities. However,…

Computation and Language · Computer Science 2022-10-28 Hassan Soliman

Facial expression analysis is central to understanding human behavior, yet existing coding systems such as the Facial Action Coding System (FACS) are constrained by limited coverage and costly manual annotation. In this work, we introduce…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Minh Tran , Maksim Siniukov , Zhangyu Jin , Mohammad Soleymani

With high-throughput biotechnologies generating unprecedented quantities of data, researchers are faced with the challenge of locating and comparing an exponentially growing number of programs and websites dedicated to computational…

The interactions between DNA, RNA, and proteins are fundamental to biological processes, as illustrated by the central dogma of molecular biology. Although modern biological pre-trained models have achieved great success in analyzing these…

Machine Learning · Computer Science 2025-12-02 Zicheng Liu , Siyuan Li , Zhiyuan Chen , Chang Yu , Qirong Yang , Yucheng Guo , Yujie Yang , Xiaoming Zhang , Stan Z. Li

Composite DNA is a recent novel method to increase the information capacity of DNA-based data storage above the theoretical limit of 2 bits/symbol. In this method, every composite symbol does not store a single DNA nucleotide but a mixture…

Information Theory · Computer Science 2025-01-22 Tuan Thanh Nguyen , Chen Wang , Kui Cai , Yiwei Zhang , Zohar Yakhini

At the core of high throughput DNA sequencing platforms lies a bio-physical surface process that results in a random geometry of clusters of homogenous short DNA fragments typically hundreds of base pairs long - bridge amplification. The…

Genomics · Quantitative Biology 2015-08-13 Eliza O'Reilly , Francois Baccelli , Gustavo de Veciana , Haris Vikalo

Enzyme Commission (EC) numbers, which associate a protein sequence with the biochemical reactions it catalyzes, are essential for the accurate understanding of enzyme functions and cellular metabolism. Many ab-initio computational…

Machine Learning · Computer Science 2023-06-07 Zhenkun Shi , Qianqian Yuan , Ruoyu Wang , Hoaran Li , Xiaoping Liao , Hongwu Ma

Advances in genome sequencing technologies generate massive amounts of sequence data that are increasingly analyzed and shared through public repositories. On-demand infrastructure services on cloud computing platforms enable the processing…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-03-20 Junseok Park , Eduardo A. Maury , Changhoon Oh , Donghoon Shin , Danielle Denisko , Eunjung Alice Lee

A software program which aims to provide an exploration capability over the Search Space of potential drug molecules. The program explores the search space by generating random molecules, determining their fitness and then breeding a new…

Neural and Evolutionary Computing · Computer Science 2014-03-20 Mark Shackelford

Electroencephalography (EEG) decoding is a challenging task due to the limited availability of labelled data. While transfer learning is a promising technique to address this challenge, it assumes that transferable data domains and task are…

Signal Processing · Electrical Eng. & Systems 2023-08-07 Bruno Aristimunha , Raphael Y. de Camargo , Walter H. Lopez Pinaya , Sylvain Chevallier , Alexandre Gramfort , Cedric Rommel

Neuro-encoded expression programming(NEEP) that aims to offer a novel continuous representation of combinatorial encoding for genetic programming methods is proposed in this paper. Genetic programming with linear representation uses…

Neural and Evolutionary Computing · Computer Science 2021-04-12 Aftab Anjum , Fengyang Sun , Lin Wang , Jeff Orchard

In real-world data science and enterprise decision-making, critical information is often fragmented across directly queryable structured sources (e.g., SQL, CSV) and "zombie data" locked in unstructured visual documents (e.g., scanned…

Artificial Intelligence · Computer Science 2026-01-30 Ruyi Qi , Zhou Liu , Wentao Zhang

Peoples' activities and opinions recorded as digital traces online, especially on social media and other web-based platforms, offer increasingly informative pictures of the public. They promise to allow inferences about populations beyond…

Computers and Society · Computer Science 2021-06-04 Indira Sen , Fabian Floeck , Katrin Weller , Bernd Weiss , Claudia Wagner

Motivation: The gene content regulates the biology of an organism. It varies between species and between individuals of the same species. Although tools have been developed to identify gene content changes in bacterial genomes, none is…

Genomics · Quantitative Biology 2024-05-30 Heng Li , Maximillian Marin , Maha Reda Farhat

The human brain represents an object by small elements and distinguishes two objects based on the difference in elements. Discovering the distinctive elements of high-dimensional datasets is therefore critical in numerous perception-driven…

Computer Vision and Pattern Recognition · Computer Science 2024-10-10 Md Tauhidul Islam , Lei Xing

This paper introduces a new concept. We intend to give life to a software agent. A software agent is a computer program that acts on a user's behalf. We put a DNA inside the agent. DNA is a simple text, a whole roadmap of a network of…

Multiagent Systems · Computer Science 2023-03-28 Arash Vaezi

Counting people or objects with significantly varying scales and densities has attracted much interest from the research community and yet it remains an open problem. In this paper, we propose a simple but an efficient and effective…

Computer Vision and Pattern Recognition · Computer Science 2019-04-18 Lei Liu , Jie Jiang , Wenjing Jia , Saeed Amirgholipour , Michelle Zeibots , Xiangjian He
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